Gene expression on acute myocardial stress. Induction by hypoxia, ischemia, reperfusion, hyperthermia and oxidative stress

THE HEAT-SHOCK PROTEINS

1988 • 5,214 citations

Studies and Perspectives of Protein Kinase C

1986 • 5,148 citations

The Leucine Zipper: A Hypothetical Structure Common to a New Class of DNA Binding Proteins

1988 • 3,479 citations

Purified transcription factor AP-1 interacts with TPA-inducible enhancer elements

1987 • 2,107 citations

Cells in Stress: Transcriptional Activation of Heat Shock Genes

1993 • 1,429 citations

Human Proto-Oncogene c- jun Encodes a DNA Binding Protein with Structural and Functional Properties of Transcription Factor AP-1

1987 • 1,353 citations

DNA-dependent transcription of adenovirus genes in a soluble whole-cell extract.

1980 • 1,285 citations

Rapid increase of an immediate early gene messenger RNA in hippocampal neurons by synaptic NMDA receptor activation

1989 • 1,014 citations

Protooncogene induction and reprogramming of cardiac gene expression produced by pressure overload.

1988 • 877 citations

Stress protein systems of mammalian cells

1986 • 564 citations

Constitutive c-myc oncogene expression blocks mouse erythroleukaemia cell differentiation but not commitment

1986 • 536 citations

Heat-shock protein induction in rat hearts. A direct correlation between the amount of heat-shock protein induced and the degree of myocardial protection.

1994 • 364 citations

Heat shock protein induction in rat hearts. A role for improved myocardial salvage after ischemia and reperfusion?

1992 • 323 citations

Heat-shock response and limitation of tissue necrosis during occlusion/reperfusion in rabbit hearts.

1993 • 278 citations

Regulation of heat shock protein 70 gene expression by c-myc

1984 • 270 citations

Rapid expression of heat shock protein in the rabbit after brief cardiac ischemia.

1991 • 265 citations

RNA polymerase III

1993 • 240 citations

Trauma-Induced Protein in Rat Tissues: A Physiological Role for a "Heat Shock" Protein?

1981 • 233 citations

Molecular adaptation of cellular defences following preconditioning of the heart by repeated ischaemia

1993 • 218 citations

Alpha 1-adrenoceptor-mediated phosphoinositide breakdown and inotropic response in rat left ventricular papillary muscles.

1988 • 210 citations

Identification and molecular analysis of oxyR-regulated promoters important for the bacterial adaptation to oxidative stress

1989 • 198 citations

Molecular adaptation of vascular endothelial cells to oxidative stress

1993 • 182 citations

Stress proteins and myocardial protection

1992 • 169 citations

Proto-oncogene expression in porcine myocardium subjected to ischemia and reperfusion.

1992 • 154 citations

Redox-activated expression of the cytosolic copper/zinc superoxide dismutase gene in Nicotiana.

1993 • 151 citations

Translocation and enhancement of phosphotransferase activity of protein kinase C following exposure in mouse epidermal cells to oxidants.

1989 • 132 citations

Manganese Superoxide Dismutase: A Hepatic Acute Phase Protein Regulated by Interleukin-6 and Glucocorticoids*

1991 • 128 citations

Effects of ischemia and perfusion temperature on the synthesis of stress-induced (heart shock) proteins in isolated and perfused rat hearts*

1987 • 127 citations

Association between the mammalian 110,000-dalton heat-shock protein and nucleoli.

1983 • 121 citations

Myocardial protection after whole body heat stress in the rabbit is dependent on metabolic substrate and is related to the amount of the inducible 70-kD heat stress protein.

1994 • 120 citations

Interleukin 1 and tumour necrosis factor increase phosphorylation of the small heat shock protein

1989 • 117 citations

Ischemia induces changes in the level of mRNAs coding for stress protein 71 and creatine kinase M.

1988 • 116 citations

The OxyR regulon

1990 • 110 citations

Demonstration of free radical generation in the "stunned" myocardium in the conscious dog and identification of major differences between conscious and open-chest dogs.

1993 • 109 citations

Heat shock. A new approach for myocardial preservation in cardiac surgery.

1992 • 104 citations

Interleukin-1 alpha preconditioning reduces myocardial ischemia reperfusion injury.

1993 • 97 citations

Pathophysiology of Reperfusion Injury

1992 • 97 citations

Oxidants induce phosphorylation of ribosomal protein S6.

1988 • 91 citations

A single myocardial stretch or decreased systolic fiber shortening stimulates the expression of heat shock protein 70 in the isolated, erythrocyte-perfused rabbit heart.

1991 • 86 citations

Analysis of RNA for transcripts for catalase and SP71 in rat hearts after in vivo hyperthermia

1991 • 84 citations

Separate Regulation of Heme Oxygenase and Heat Shock Protein 70 mRNA Expression in the Rat Heart by Hemodynamic Stress

1993 • 80 citations

Comparisons of ESR and HPLC methods for the detection of OH. radicals in ischemic/reperfused hearts

1993 • 74 citations

Regulation of manganese superoxide dismutase: IL-1 and TNF induction in pulmonary artery and microvascular endothelial cells

1992 • 74 citations

Differential Expression of hsp70 Stress Proteins in Human Endothelial Cells Exposed to Heat Shock and Hydrogen Peroxide

1991 • 73 citations

Isolation and immunological characterization of a glucose-regulated fibroblast cell surface glycoprotein and its nonglycosylated precursor

1978 • 71 citations

Oxygen Radicals: Systemic Events and Disease Processes

1991 • 69 citations

Enhanced phosphodiesteratic breakdown and turnover of phosphoinositides during reperfusion of ischemic rat heart.

1988 • 67 citations

Effect of alpha-adrenergic stimulation on activation of protein kinase C and phosphorylation of proteins in intact rabbit hearts.

1992 • 65 citations

Expression of heat shock proteins in the normal and stunned porcine myocardium

1993 • 63 citations

Phospholipase D signaling in ischemic heart

1992 • 59 citations

Enhanced gene expression of calcium regulatory proteins in stunned porcine myocardium

1993 • 49 citations

Gene Expression during Myocardial Adaptation to Ischemia and Reperfusion a

1994 • 47 citations

Whole body heat stress fails to limit infarct size in the reperfused rabbit heart

1992 • 42 citations

Evidence that phosphoinositide response is mediated by α1-adrenoceptor stimulation, but not linked with excitation-contraction coupling in cardiac muscle

1986 • 36 citations

Preconditioning of heart by repeated stunning. Adaptive modification of antioxidative defense system.

1992 • 36 citations

Improved postischemic ventricular functional recovery by amphetamine is linked with its ability to induce heat shock

1994 • 34 citations

Elevated glutathione S‐transferase gene expression is an early event during steroid‐induced lymphocyte apoptosis

1993 • 33 citations

Molecular Biology of the Coronary Vascular and Myocardial Responses to Ischemia

1992 • 32 citations

Induction of Differential Heat Shock Gene Expression in Heart, Lung, Liver, Brain and Kidney by a Sympathomimetic Drug, Amphetamine

1993 • 29 citations

4 Mechanism of Free Radical Generation during Reperfusion of Ischemic Myocardium

2015 • 22 citations

Angiogenesis by slow coronary artery occlusion in the pig heart: Expression of different growth factors mRNAs

1989 • 14 citations

Myocardial preservation with hypothermic fibrillatory arrest for coronary grafting

1990 • 4 citations