Catalytic properties of the human cytochrome P450 2E1 produced by cDNA expression in mammalian cells

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

The Carbon Monoxide-binding Pigment of Liver Microsomes

1964 • 11,832 citations

Some properties of a detergent-solubilized NADPH-cytochrome c(cytochrome P-450) reductase purified by biospecific affinity chromatography.

1976 • 1,180 citations

Role of human cytochrome P-450 IIE1 in the oxidation of many low molecular weight cancer suspects

1991 • 1,173 citations

Vaccinia virus expression vector: coexpression of beta-galactosidase provides visual screening of recombinant virus plaques.

1985 • 789 citations

Reactions and significance of cytochrome P-450 enzymes

1991 • 596 citations

Oxidative and reductive metabolism by cytochrome P450 2E1

1992 • 557 citations

Purification and characterization of a unique isozyme of cytochrome P-450 from liver microsomes of ethanol-treated rabbits.

1982 • 537 citations

p-Nitrophenol hydroxylation. A microsomal oxidation which is highly inducible by ethanol.

1985 • 412 citations

Hydroxylation of p-nitrophenol by rabbit ethanol-inducible cytochrome P-450 isozyme 3a.

1986 • 341 citations

Characterization of a major form of rat hepatic microsomal cytochrome P-450 induced by isoniazid.

1985 • 311 citations

[22] The measurement of difference spectra: Application to the cytochromes of microsomes

1978 • 294 citations

The Binding of Cytochrome b5 to Liver Microsomes

1972 • 286 citations

Paracetamol metabolism and toxicity in isolated hepatocytes from rat and mouse

1978 • 211 citations

Cytochrome b5 reduction by NADPH-cytochrome P-450 reductase.

1979 • 199 citations

Acetone-inducible cytochrome P-450: Purification, catalytic activity, and interaction with cytochrome b5

1986 • 135 citations

Identification of ethanol-inducible P450 isozyme 3a (P450IIE1) as a benzene and phenol hydroxylase

1989 • 134 citations

Estradiol Metabolism by Complementary Deoxyribonucleic Acid-Expressed Human Cytochrome P450s

1990 • 129 citations

The Interaction of Porphyrins and Metalloporphyrins with Apocytochrome b5

1964 • 127 citations

Evidence for Random Distribution and Translational Movement of Cytochrome b5 in Endoplasmic Reticulum

1974 • 123 citations

The binding of cytochrome b5 to phospholipid vesicles and biological membranes. Effect of orientation on intermembrane transfer and digestion by carboxypeptidase Y.

1979 • 123 citations

Purification and characterization of ethanol-inducible human hepatic cytochrome P-450HLj

1987 • 112 citations

N-demethylation of N-nitrosodimethylamine catalyzed by purified rat hepatic microsomal cytochrome P-450: Isozyme specificity and role of cytochrome b5

1986 • 103 citations

Roles of cytochrome P450IIE1 in the dealkylation and denitrosation of N-nitrosodimethylamine and N-nitrosodiethylamine in rat liver microsomes

1990 • 101 citations

Effects of cytochrome b5 on cytochrome P-450-catalyzed reactions. Studies with manganese-substituted cytochrome b5.

1984 • 91 citations

Quantitative determination of the glutathione, cysteine, and N-acetyl cysteine conjugates of acetaminophen by high-pressure liquid chromatography

1977 • 87 citations

Induction of a high affinity nitrosamine demethylase in rat liver microsomes by acetone and isopropanol

1983 • 78 citations

Effects of conditions for reconstitution with cytochrome b5 on the formation of products in cytochrome P-450-catalyzed reactions.

1986 • 70 citations

Immunochemical studies on the metabolism of nitrosamines by ethanol-inducible cytochrome P-450

1985 • 67 citations

Incorporation of purified cytochrome into liver microsomal membranes

1973 • 62 citations

Induction of cytochromes P450IIE1 and P450IIB1 by secondary ketones and the role of P450IIE1 in chloroform metabolism

1989 • 58 citations

Metabolism and activation of N-nitrosodimethylamine by hamster and rat microsomes: comparative study with weanling and adult animals.

1987 • 54 citations

Kinetics analysis of cytochrome b5 reduction by (ethylenediaminetetraacetato)ferrate(2-) ion

1982 • 53 citations

Deuterium isotope effect on denitrosation and demethylation of N-nitrosodimethylamine by rat liver microsomes.

1987 • 51 citations

Diethyl ether as a substrate for acetone/ethanol-inducible cytochrome P-450 and as an inducer for cytochrome(s) P-450.

1988 • 50 citations

[58] Induction, purification, and characterization of cytochrome P450IIE

1991 • 46 citations

Binding of homogeneous cytochrome b5 to rat liver microsomes effect on N-demethylation reactions

1975 • 26 citations

Deuterium isotope effect in the interaction of N-nitrosodimethylamine, ethanol, and related compounds with cytochrome P-450IIE1

1991 • 20 citations

Kinetic investigation of rat liver microsomal electron transport from NADH to cytochrome P-450.

1982 • 15 citations

Hamster hepatic cytochrome b5: purifications, immunochemical properties, and in vitro synthesis

1985 • 3 citations