A single GTP-binding protein regulates K+-channels coupled with dopamine, histamine and acetylcholine receptors

Isolation of two proteins with high affinity for guanine nucleotides from membranes of bovine brain.

1984 • 1,300 citations

GTP-binding proteins couple cardiac muscarinic receptors to a K channel

1985 • 868 citations

Purification and properties of the inhibitory guanine nucleotide regulatory unit of brain adenylate cyclase.

1984 • 585 citations

Uncoupling of cardiac muscarinic and β-adrenergic receptors from ion channels by a guanine nucleotide analogue

1985 • 527 citations

Ionic mechanisms and receptor properties underlying the responses of molluscan neurones to 5‐hydroxytryptamine

1974 • 256 citations

Characterization of α2-adrenoceptors which increase potassium conductance in rat locus coeruleus neurones

1985 • 246 citations

Pertussis toxin blocks the outward currents evoked by opiate and α2-agonists in locus coeruleus neurons

1986 • 241 citations

Substantia gelatinosa neurones hyperpolarized in vitro by enkephalin

1983 • 236 citations

Ionic mechanism of a two‐component cholinergic inhibition in Aplysia neurones

1972 • 222 citations

Hyperpolarization of serotonergic neurons by serotonin and LSD: Studies in brain slices showing increased K+ conductance

1984 • 221 citations

The A protomer of islet-activating protein, pertussis toxin, as an active peptide catalyzing ADP-ribosylation of a membrane protein

1983 • 215 citations

Mechanisms of slow postsynaptic potentials

1981 • 124 citations

Multiple actions of a molluscan cardioexcitatory neuropeptide and related peptides on identified Helix neurones.

1984 • 117 citations

Receptors for gamma-aminobutyric acid (GABA) on aplysia neurons

1978 • 107 citations

The Ionic Permeability Changes during Acetylcholine-Induced Responses of Aplysia Ganglion Cells

1968 • 94 citations

GTP hydrolysis by pure Ni, the inhibitory regulatory component of adenylyl cyclases.

1984 • 89 citations

Certain Slow Synaptic Responses: Their Properties and Possible Underlying Mechanisms

1980 • 75 citations

Pertussis toxin treatment blocks hyperpolarization by muscarinic agonists in chick atrium.

1985 • 71 citations

Two pharmacologically distinct histamine receptors mediating membrane hyperpolarization on identified neurons of Aplysia californica

1979 • 71 citations

Effect of pertussis toxin on normorphine‐dependence and on acute inhibitory effects of normorphine and clonidine in guinea‐pig isolated ileum

1984 • 52 citations

Pertussis toxin blocks the action of morphine, norepinephrine and clonidine on isolated guinea-pig ileum

1984 • 41 citations

Interactions between three slow potassium responses controlled by three distinct receptors in Aplysia neurones

1982 • 40 citations

Somatostatin inhibition of glucose-induced electrical activity in cultured rat islet cells

1977 • 25 citations

Examination of the role of the electrogenic sodium pump in the adrenaline‐induced hyperpolarization of amphibian neurones.

1984 • 18 citations