Effect of phenobarbital on the expression of bile salt and organic anion transporters of rat liver

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Measurement of protein using bicinchoninic acid

1985 • 17,516 citations

HIGH-YIELD PREPARATION OF ISOLATED RAT LIVER PARENCHYMAL CELLS

1969 • 4,428 citations

Assay of proteins in the presence of interfering materials

1976 • 3,217 citations

The Sister of P-glycoprotein Represents the Canalicular Bile Salt Export Pump of Mammalian Liver

1998 • 933 citations

Congenital Jaundice in Rats with a Mutation in a Multidrug Resistance-Associated Protein Gene

1996 • 827 citations

Intuitive Biostatistics.

1997 • 799 citations

Expression cloning of a rat liver Na(+)-independent organic anion transporter.

1994 • 535 citations

Functional expression cloning and characterization of the hepatocyte Na+/bile acid cotransport system.

1991 • 479 citations

Mechanisms and regulation of bile secretion

1991 • 402 citations

Isolation of a multispecific organic anion and cardiac glycoside transporter from rat brain

1997 • 396 citations

Molecular Characterization and Tissue Distribution of a New Organic Anion Transporter Subtype (oatp3) That Transports Thyroid Hormones and Taurocholate and Comparison with oatp2

1998 • 338 citations

[Drugs and the liver].

1970 • 278 citations

Expression and localization of the conjugate export pump encoded by the MRP2 (cMRP/cMOAJ) gene in liver

1997 • 269 citations

Hepatic expression of multidrug resistance-associated protein-like proteins maintained in eisai hyperbilirubinemic rats.

1998 • 265 citations

Characterization of inducible nature of MRP3 in rat liver

2000 • 255 citations

Canalicular multispecific organic anion transporter/multidrug resistance protein 2 mediates low-affinity transport of reduced glutathione

1999 • 246 citations

In situ localization of the hepatocytic na+/taurocholate cotransporting polypeptide in rat liver

1994 • 221 citations

Transport Function and Hepatocellular Localization of mrp6 in Rat Liver

2000 • 218 citations

cDNA cloning and inducible expression of human multidrug resistance associated protein 3 (MRP3)¹

1998 • 214 citations

Localization and function of the organic anion–transporting polypeptide Oatp2 in rat liver

1999 • 209 citations

Studies of Y and Z, two hepatic cytoplasmic organic anion-binding proteins: effect of drugs, chemicals, hormones, and cholestasis

1971 • 207 citations

The effect of phenobarbital on the metabolism and excretion of thyroxine in rats

1989 • 189 citations

Molecular mechanisms of hepatic bile salt transport from sinusoidal blood into bile

1995 • 186 citations

Increased thyroxine turnover and thyroidal function after stimulation of hepatocellular binding of thyroxine by phenobarbital

1968 • 161 citations

Polyspecific drug and steroid clearance by an organic anion transporter of mammalian liver.

1996 • 152 citations

Hepatobiliary transport

2000 • 146 citations

Identification of organic anion transporting polypeptide 4 (Oatp4) as a major full-length isoform of the liver-specific transporter-1 (rlst-1) in rat liver

2000 • 144 citations

Polyspecific substrate uptake by the hepatic organic anion transporter Oatp1 in stably transfected CHO cells

1999 • 138 citations

Canalicular Bile Secretion in Man STUDIES UTILIZING THE BILIARY CLEARANCE OF [14C]MANNITOL

1974 • 129 citations

Effect of phenobarbital on bile flow and bile salt excretion in the rat

1971 • 121 citations

Effect of antisense oligonucleotides on the expression of hepatocellular bile acid and organic anion uptake systems in Xenopus laevis oocytes

1996 • 120 citations

The role of phospholipids in bile formation: what can we learn from animals and human disease?

2000 • 115 citations

A barbiturate-regulated protein binding to a common sequence in the cytochrome P450 genes of rodents and bacteria.

1991 • 112 citations

A domain-specific marker for the hepatocyte plasma membrane: localization of leucine aminopeptidase to the bile canalicular domain.

1983 • 111 citations

Studies on the mechanism of phenobarbital-enhanced sulfobromophthalein disappearance.

1968 • 109 citations

Isolation and characterization of rough endoplasmic reticulum associated with mitochondria from normal rat liver

1981 • 103 citations

Molecular characterization and functional regulation of a novel rat liver-specific organic anion transporter rlst-1

1999 • 102 citations

Expression of the liver Na+-independent organic anion transporting polypeptide (oatp-1) in rats with bile duct ligation

1997 • 99 citations

Functional expression of the rat liver canalicular isoform of the multidrug resistance‐associated protein

1997 • 91 citations

Effects of phenobarbital on the plasma disappearance and biliary excretion of drugs in rats.

1970 • 87 citations

Canalicular multispecific organic anion transporter/multidrug resistance protein 2 mediates low-affinity transport of reduced glutathione

1999 • 81 citations

Effect of microsomal enzyme inducers on the biliary excretion of cardiac glycosides.

1974 • 75 citations

Preserved organic anion transport in mutant TR- rats with a hepatobiliary secretion defect

1993 • 68 citations

Hepatocellular transport of bile acids. Evidence for distinct subcellular localizations of electrogenic and ATP-dependent taurocholate transport in rat hepatocytes.

1994 • 62 citations

Extent and character of phenobarbital-mediated changes in gene expression in the liver.

1997 • 59 citations

Hepatocellular Transport of Bile Acids

1993 • 57 citations

Selective induction by phenobarbital of the electrogenic transport of glutathione and organic anions in rat liver canalicular membrane vesicles

1993 • 43 citations

Drugs and the liver—I

1974 • 42 citations

Identification and characterization of a basolateral dicarboxylate/cholate antiport system in rat hepatocytes

1995 • 26 citations

Hepatic blood flow and enzyme induction in the rat

1975 • 26 citations

Dose-Related Effects of Phenobarbital on Hepatic Microsomal Enzymes

1983 • 22 citations

Enhanced sulfobromophthalein disappearance in mice pretreated with various drugs

1965 • 20 citations

Bile Flow and Biliary Excretion Rate of Some Organic Anions in Phenobarbital-Pretreated Rats

1978 • 19 citations

Biliary excretion of 3 H-digitoxin: modification by bile salts and phenobarbital.

1973 • 17 citations

Phenobarbital-enhanced biliary excretion of administered unconjugated and conjugated sulfobromophthalein (BSP) in the rat

1975 • 13 citations

STUDIES UTILIZING THE BILIARY CLEARANCE OF (14C)MANNITOL

1974 • 12 citations

The Effects of Hepatic Microsomal Enzyme Inducers on the Pharmacokinetics of Ouabain after Portal and Systemic Administration to Rats

1995 • 8 citations

Induction of a dose-related increase in sulfobromophthalein uptake velocity in freshly isolated rat hepatocytes by phenobarbital

1994 • 7 citations

Increased Sulfobromophthalein Clearance in a Patient Receiving Phenobarbital and Other Anticonvulsant Drugs

1975 • 7 citations

High affinity uptake by isolated rat hepatocytes of a linear pseudo-hexapeptide, ditekiren

1997 • 3 citations

The effects of pretreatment with phenobarbital (PB) and sulfobromophthalein (BSP) on the metabolism and the biliary excretion of BSP in the rat.

1979 • 2 citations

Biliary Excretion of Ouabain in Isolated Perfused Rat Liver after Treatment with Microsomal Enzyme Inducers1

1976 • 2 citations