Canalicular multispecific organic anion transporter/multidrug resistance protein 2 mediates low-affinity transport of reduced glutathione

Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: Applications to mammalian blood and other tissues

1969 • 6,007 citations

Analysis of expression of cMOAT (MRP2), MRP3, MRP4, and MRP5, homologues of the multidrug resistance-associated protein gene (MRP1), in human cancer cell lines.

1997 • 889 citations

Congenital Jaundice in Rats with a Mutation in a Multidrug Resistance-Associated Protein Gene

1996 • 827 citations

cDNA Cloning of the Hepatocyte Canalicular Isoform of the Multidrug Resistance Protein, cMrp, Reveals a Novel Conjugate Export Pump Deficient in Hyperbilirubinemic Mutant Rats

1996 • 641 citations

Drug export activity of the human canalicular multispecific organic anion transporter in polarized kidney MDCK cells expressing cMOAT (MRP2) cDNA.

1998 • 621 citations

Multidrug Resistance Protein (MRP)-mediated Transport of Leukotriene C4 and Chemotherapeutic Agents in Membrane Vesicles

1996 • 555 citations

A mutation in the human canalicular multispecific organic anion transporter gene causes the Dubin-Johnson syndrome

1997 • 551 citations

Role of glutathione in the export of compounds from cells by the multidrug-resistance-associated protein.

1995 • 501 citations

A human canalicular multispecific organic anion transporter (cMOAT) gene is overexpressed in cisplatin-resistant human cancer cell lines with decreased drug accumulation.

1996 • 473 citations

Reactions of arsenic(III) and arsenic(V) species with glutathione

1993 • 456 citations

The Yeast Cadmium Factor Protein (YCF1) Is a Vacuolar Glutathione S-Conjugate Pump

1996 • 442 citations

Hepatobiliary secretion of organic compounds; molecular mechanisms of membrane transport

1995 • 385 citations

Biology of the multidrug resistance-associated protein, MRP

1996 • 367 citations

A yeast metal resistance protein similar to human cystic fibrosis transmembrane conductance regulator (CFTR) and multidrug resistance-associated protein.

1994 • 364 citations

Hereditary Chronic Conjugated Hyperbilirubinemia in Mutant Rats Caused by Defective Hepatic Anion Transport

1985 • 352 citations

Analysis of the expression of MRP, the gene for a new putative transmembrane drug transporter, in human multidrug resistant lung cancer cell lines

1994 • 315 citations

Molecular cloning of canalicular multispecific organic anion transporter defective in EHBR

1997 • 294 citations

Immunochemical detection of the multidrug resistance-associated protein MRP in human multidrug-resistant tumor cells by monoclonal antibodies.

1994 • 284 citations

Evidence that the multidrug resistance protein (MRP) functions as a co-transporter of glutathione and natural product toxins.

1997 • 277 citations

Transport of glutathione conjugates and glucuronides by the multidrug resistance proteins MRP1 and MRP2.

1997 • 260 citations

Mutations in the canilicular multispecific organic anion transporter (cMOAT) gene, a novel ABC transporter, in patients with hyperbilirubinemia II/Dubin-Johnson syndrome

1998 • 259 citations

A canalicular multispecific organic anion transporter (cMOAT) antisense cDNA enhances drug sensitivity in human hepatic cancer cells.

1997 • 249 citations

Hepatobiliary transport of glutathione and glutathione conjugate in rats with hereditary hyperbilirubinemia.

1989 • 172 citations

Biliary excretion of glutathione and glutathione disulfide in the rat. Regulation and response to oxidative stress.

1984 • 166 citations

Canalicular transport of reduced glutathione in normal and mutant Eisai hyperbilirubinemic rats.

1992 • 162 citations

Transport of glutathione prostaglandin A conjugates by the multidrug resistance protein 1

1997 • 138 citations

Sinusoidal efflux of glutathione in the perfused rat liver. Evidence for a carrier-mediated process.

1985 • 136 citations

Alkaline hydrolysis of N-ethylmaleimide allows a rapid assay of glutathione disulfide in biological samples

1986 • 87 citations

The Mechanism of Biliary Secretion of Reduced Glutathione

1983 • 74 citations

Preserved organic anion transport in mutant TR- rats with a hepatobiliary secretion defect

1993 • 68 citations

ATP-dependent multispecific organic anion transport system in rat erythrocyte membrane vesicles

1992 • 56 citations

Expression cloning of a rat hepatic reduced glutathione transporter with canalicular characteristics.

1994 • 49 citations

Effect of arsenicals on biliary excretion of endogenous glutathione and xenobiotics with glutathione-dependent hepatobiliary transport

1991 • 46 citations

ATP-dependent transport of reduced glutathione in yeast secretory vesicles

1998 • 35 citations

Increased biliary excretion of glutathione is generated by the glutathione-dependent hepatobiliary transport of antimony and bismuth

1992 • 34 citations

Sulfobromophthalein inhibition of glutathione and methylmercury secretion into bile

1985 • 29 citations

Species variations in biliary excretion of glutathione-related thiols and methylmercury

1988 • 28 citations