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Predicting Adverse Drug Reactions Using Publicly Available PubChem BioAssay Data

Data up to Jan 2025

Published2011
Citations79
References38

Total Citations Per Year

Abstract

References (38)

A new look at the statistical model identification

1974 • 46,507 citations

Incidence of Adverse Drug Reactions in Hospitalized Patients

1998 • 4,749 citations

The Unified Medical Language System (UMLS): integrating biomedical terminology

2003 • 3,863 citations

DrugBank: a comprehensive resource for in silico drug discovery and exploration

2005 • 3,635 citations

ROCR: visualizing classifier performance in R

2005 • 3,055 citations

Signal integration by JNK and p38 MAPK pathways in cancer development

2009 • 2,369 citations

Use of proportional reporting ratios (PRRs) for signal generation from spontaneous adverse drug reaction reports

2001 • 1,267 citations

PubChem: Integrated Platform of Small Molecules and Biological Activities

2008 • 1,219 citations

Continuous culture of human lymphoblasts from peripheral blood of a child with acute leukemia

1965 • 1,213 citations

The Medical Dictionary for Regulatory Activities (MedDRA)

1999 • 1,126 citations

Identifying genetic risk factors for serious adverse drug reactions: current progress and challenges

2007 • 377 citations

Glutathione transferases as mediators of signaling pathways involved in cell proliferation and cell death

2010 • 374 citations

Analysis of Pharmacology Data and the Prediction of Adverse Drug Reactions and Off‐Target Effects from Chemical Structure

2007 • 317 citations

An overview of the PubChem BioAssay resource

2009 • 274 citations

Physicians' knowledge and attitudes regarding the spontaneous reporting system for adverse drug reactions

2002 • 218 citations

Biological spectra analysis: Linking biological activity profiles to molecular structure

2004 • 182 citations

Analysis of drug-induced effect patterns to link structure and side effects of medicines

2005 • 156 citations

Nitazoxanide: a new broad spectrum antiparasitic agent

2004 • 155 citations

Systematic analysis of genome-wide fitness data in yeast reveals novel gene function and drug action

2010 • 114 citations

Design and Implementation of a National Clinical Trials Registry

2000 • 106 citations

Prediction of Adverse Drug Reactions Using Decision Tree Modeling

2010 • 95 citations

eAnti-interleukin-1 effects of diacerein and rhein in human osteoarthritic synovial tissue and cartilage cultures

1999 • 93 citations

In Silico Elucidation of the Molecular Mechanism Defining the Adverse Effect of Selective Estrogen Receptor Modulators

2007 • 86 citations

Thiazolides inhibit growth and induce glutathione‐S‐transferase Pi (GSTP1)‐dependent cell death in human colon cancer cells

2008 • 82 citations

Allergologia et Immunopathologia.

1973 • 78 citations

Drug Development and the FDA's Critical Path Initiative

2006 • 73 citations

Report of the IWGT working group on strategy/interpretation for regulatory in vivo tests

2006 • 62 citations

Diacerein inhibits the synthesis of resorptive enzymes and reduces osteoclastic differentiation/survival in osteoarthritic subchondral bone: a possible mechanism for a protective effect against subchondral bone remodelling

2008 • 58 citations

MMP13 mediates cell cycle progression in melanocytes and melanoma cells: in vitro studies of migration and proliferation

2010 • 58 citations

Data-Driven Methods to Discover Molecular Determinants of Serious Adverse Drug Events

2009 • 50 citations

Association between glutathione-S-transferase GSTP1 genotypes, GSTP1 over-expression, and outcome in epithelial ovarian cancer

2004 • 46 citations

The Inhibition Mechanism of Histamine Release by N-(3,4-Dimethoxycinnamoyl) Anthranilic Acid

1985 • 43 citations

Tranilast inhibits collagen synthesis in normal, scleroderma and keloid fibroblasts at a late passage culture but not at an early passage culture

1995 • 31 citations

A survey of across-target bioactivity results of small molecules in PubChem

2009 • 30 citations

Expression of matrix metalloproteinases and their endogenous tissue inhibitors in skin lesions from patients with tuberous sclerosis

2004 • 26 citations

Adverse drug reactions and pharmacogenomics: recent advances

2007 • 25 citations

In Silico Functional Profiling of Small Molecules and Its Applications

2008 • 17 citations

New approach to the mechanism of antiasthmatic action of Tranilast.

1990 • 6 citations

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Predicting Adverse Drug Reactions Using Publicly Available PubChem BioAssay Data (2011) – Clinical Pharmacology & Therapeutics | Metascience Observatory Explorer