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HUS and TTP: Variable expression of a single entity

Data up to Jan 2025

Published1987
Citations261
References169

Total Citations Per Year

Abstract

References (169)

Culture of Human Endothelial Cells Derived from Umbilical Veins. IDENTIFICATION BY MORPHOLOGIC AND IMMUNOLOGIC CRITERIA

1973 • 6,904 citations

Unusually Large Plasma Factor VIII: von Willebrand Factor Multimers in Chronic Relapsing Thrombotic Thrombocytopenic Purpura

1982 • 1,105 citations

SPORADIC CASES OF HAEMOLYTIC-URAEMIC SYNDROME ASSOCIATED WITH FAECAL CYTOTOXIN AND CYTOTOXIN-PRODUCING ESCHERICHIA COLI IN STOOLS

1983 • 1,036 citations

THROMBOTIC THROMBOCYTOPENIC PURPURA

1966 • 905 citations

Para-aminosalicylic acid in tuberculosis; early results of clinical trials.

1947 • 797 citations

Thrombotic thrombocytopenic purpura : report of 16 cases and review of the literature

1966 • 764 citations

Effects of prostacyclin (PGX) on cyclic AMP concentrations in human platelets

1977 • 601 citations

[Hemolytic-uremic syndrome: bilateral necrosis of the renal cortex in acute acquired hemolytic anemia].

1955 • 546 citations

Culture of vascular endothelium.

1976 • 532 citations

AN ACUTE FEBRILE PLEIOCHROMIC ANEMIA WITH HYALINE THROMBOSIS OF THE TERMINAL ARTERIOLES AND CAPILLARIES

1925 • 523 citations

Platelet and Fibrinogen Consumption in Man

1972 • 492 citations

Nephrotoxicity of Cyclosporin a after Allogeneic Marrow Transplantation

1981 • 364 citations

Treatment of Thrombotic Thrombocytopenic Purpura with Plasma

1977 • 362 citations

Localisation and stimulation of prostacyclin production in vascular cells

1978 • 356 citations

Hemolytic-Uremic Syndrome after Shigellosis

1978 • 351 citations

Cyclosporin-induced endothelial cell injury.

1986 • 331 citations

Thrombotic Thrombocytopenic Purpura

1981 • 319 citations

HqMOLYTIC-URqMIC SYNDROME: DEFICIENCY OF PLASMA FACTOR(S) REGULATING PROSTACYCLIN ACTIVITY?

1978 • 294 citations

Hypoxæmia after Anæsthesia

1965 • 284 citations

Estimated rate of prostacyclin secretion into the circulation of normal man.

1981 • 271 citations

The Hemolytic-Uremic Syndrome

1973 • 269 citations

The hemolytic-uremic syndrome

1964 • 267 citations

Latent tissue plasminogen activator produced by human endothelial cells in culture: evidence for an enzyme-inhibitor complex.

1983 • 250 citations

Peroxidase-dependent deactivation of prostacyclin synthetase

1979 • 231 citations

Lipopolysaccharide-mediated bovine endothelial cell injury in vitro.

1983 • 215 citations

LYMPHOID MALIGNANCY

1974 • 211 citations

ELECTRO-ACUPUNCTURE AND PAIN THRESHOLD

1973 • 201 citations

Hemolytic Uremic Syndrome in Families

1975 • 201 citations

Thrombotic Microangiopathic Haemolytic Anaemia

1952 • 197 citations

Protein-C: biochemistry, physiology, and clinical implications

1983 • 194 citations

Hemolytic-Uremic Syndrome: Current Concepts and Management

1982 • 180 citations

Protein-C: biochemistry, physiology, and clinical implications

1983 • 169 citations

Coagulation and renal disease

1972 • 164 citations

THE EFFECTS OF ENDOTOXIN ON VASCULAR ENDOTHELIUM

1969 • 151 citations

Thrombotic thrombocytopenic purpura: a review.

1982 • 146 citations

Vascular Lesions: Possible Pathogenetic Basis of the Generalized Shwartzman Reaction

1970 • 144 citations

Microangiopathic Haemolytic Anaemia: Mechanisms of Red‐Cell Fragmentation: in Vitro Studies

1968 • 141 citations

Disseminated arteriolar and capillary platelet thrombosis; a morphologic study of its histogenesis.

1950 • 140 citations

Exchange transfusions in the treatment of thrombotic thrombocytopenic purpura.

1976 • 139 citations

De novo hemolytic uremic syndrome in renal transplant recipients immunosuppressed with cyclosporine.

1985 • 138 citations

Thrombotic thrombocytopenic purpura: a ten-year experience

1980 • 134 citations

The Hemolytic Uremic Syndrome

1976 • 133 citations

Neurological involvement in hemolytic‐uremic syndrome

1986 • 132 citations

Pathologic effects of plasma from patients with thrombotic thrombocytopenic purpura on platelets and cultured vascular endothelial cells

1982 • 129 citations

Haemolytic-uraemic syndrome: an analysis of prognostic features.

1983 • 128 citations

Prognostic importance of vascular lesions in acute renal failure with microangiopathic hemolytic anemia (hemolytic-uremic syndrome): Clinicopathologic study in 20 adults

1979 • 127 citations

Hemolytic Uremic Syndrome

2012 • 126 citations

Ineffectiveness of Aspirin and Dipyridamole in the Treatment of Thrombotic Thrombocytopenic Purpura

1982 • 120 citations

Abnormal VIII: von Willebrand factor patterns in the plasma of patients with the hemolytic-uremic syndrome

1984 • 117 citations

ACCELERATED PROSTACYCLIN DEGRADATION IN THROMBOTIC THROMBOCYTOPENIC PURPURA

1981 • 107 citations

Heparin therapy in the hemolytic-uremic syndrome

1973 • 101 citations

Therapy of Thrombotic Thrombocytopenic Purpura: An Overview

1981 • 100 citations

An analysis of the results of therapy in 67 cases of the hemolytic-uremic syndrome

1971 • 100 citations

Regulation of vascular prostaglandin synthesis by metabolites of arachidonic acid in perfused rabbit aorta.

1983 • 98 citations

Detection of a Platelet-Agglutinating Factor in Thrombotic Thrombocytopenic Purpura

1984 • 97 citations

Isolation of a Microtatobiote from Patients with Hemolytic-Uremic Syndrome and Thrombotic Thrombocytopenic Purpura and from Mites in the United States

1969 • 97 citations

Treatment of Thrombotic Thrombocytopenic Purpura With Vincristine

1982 • 96 citations

Therapy of chronic relapsing thrombotic thrombocytopenic purpura with prednisone and azathioprine

1985 • 95 citations

The complement system in hemolytic-uremic syndrome in childhood.

1980 • 93 citations

Novel platelet-agglutinating protein from a thrombotic thrombocytopenic purpura plasma.

1985 • 91 citations

Microangiopathic hemolytic anemia, thrombocytopenia, and renal failure in patients treated for adenocarcinoma

1981 • 89 citations

IRREVERSIBLE POST-PARTUM RENAL FAILURE<subtitle>A New Syndrome</subtitle>

1968 • 89 citations

The hemolytic-uremic syndrome: a study of renal pathologic alterations.

1969 • 88 citations

Is prostacyclin a physiologically important circulating anti-platelet agent?

1980 • 88 citations

Phenomenon of Local Tissue Reactivity.

1938 • 86 citations

Scanning electron microscopy: Morphology of aortic endothelium following injury by endotoxin and during subsequent repair

1977 • 85 citations

Serum prostacyclin binding defects in thrombotic thrombocytopenic purpura.

1985 • 84 citations

Acute renal failure of obstetric origin.

1976 • 84 citations

Treatment of the hemolytic uremic syndrome with plasma.

1979 • 83 citations

Haemolytic-Uraemic Syndrome in Typhoid Fever

1974 • 83 citations

Effects of lipopolysaccharide on human endothelial cells in culture

1983 • 82 citations

Split products of fibrin in human renal disease

1969 • 81 citations

HÆMOLYTIC URÆMIC SYNDROME IN WOMEN TAKING ORAL CONTRACEPTIVES

1973 • 77 citations

Haemolytic uraemic syndrome: therapeutic effect of plasma infusion.

1982 • 77 citations

Treatment of cancer-associated hemolytic uremic syndrome with staphylococcal protein A immunoperfusion.

1986 • 75 citations

Prostacyclin deficiency in haemolytic-uraemic syndrome.

1980 • 73 citations

Thrombotic Thrombocytopenic Purpura: A Thirty Year Review

1980 • 71 citations

Abnormalities of factor VIII related protein multimers in the haemolytic uraemic syndrome.

1984 • 71 citations

Antibodies which antagonise the effects of prostacyclin

1978 • 70 citations

PLASMA-C3 IN HqMOLYTIC-URqMIC SYNDROME AND THROMBOTIC THROMBOCYTOPENIC PURPURA

1973 • 69 citations

Le syndrome hémolytique et urémique de I’enfant

1967 • 68 citations

Enteroviruses associated with the hemolytic-uremic syndrome.

1970 • 66 citations

Uremic bleeding

1983 • 62 citations

ENDOTHELIAL SURFACE CHARGE AND ITS POSSIBLE RELATIONSHIP TO THROMBOGENESIS

1976 • 62 citations

Immunofluorescent Localization of Antihemophilic Factor Antigen and Fibrinogen in Human Renal Diseases

1974 • 61 citations

An Unusual Syndrome of Hemolytic Anemia, Thrombocytopenic Purpura and Renal Disease

1957 • 61 citations

The Hemolytic-Uremic Syndrome

1978 • 61 citations

Adult hemolytic-uremic syndrome

1980 • 60 citations

Vascular intimal components: precursors of thrombosis.

1974 • 59 citations

THE HAEMOLYTIC URAEMIC SYNDROME IN ADULTS<sup>1</sup>

1970 • 59 citations

Mitomycin-induced hemolytic uremic kidney. An experimental model in the rat.

1985 • 58 citations

Recurrence of hemolytic uremic syndrome in renal transplant recipients.

1986 • 57 citations

Inhibitor of prostacyclin production in sporadic haemolytic uraemic syndrome.

1983 • 56 citations

Aspirin and dipyridamole therapy in the hemolytic-uremic syndrome

1980 • 54 citations

Mitomycin- Induced Hemolytic-Uremic Syndrome

1983 • 54 citations

Plasma Infusion in the Treatment of Thrombotic Thrombocytopenic Purpura

1981 • 54 citations

Mitomycin-C Nephrotoxicity: A Clinico-Pathologic Study of 17 Cases

1985 • 53 citations

Hemolytic-Uremic Syndrome

1979 • 53 citations

Treatment of thrombotic thrombocytopenic purpura by exchange transfusion

1977 • 53 citations

Platelet, erythrocyte, and fibrinogen kinetics in the hemolytic-uremic syndrome of infancy

1973 • 52 citations

Hemolytic Uremic Syndrome in Adults

1980 • 52 citations

Renal Involvement in Patients with Thrombotic Thrombocytopenic Purpura

1986 • 51 citations

ENTEROVIRUSES ASSOCIATED WITH THE HEMOLYTIC-UREMIC SYNDROME

1970 • 51 citations

Thrombotic Thrombocytopenic Purpura in Childhood

1962 • 50 citations

IMMUNOFLUORESCENT AND HISTOLOGIC FINDINGS IN THE HEMOLYTIC UREMIC SYNDROME

1971 • 50 citations

Mitomycin-induced hemolytic-uremic syndrome. Successful treatment with corticosteroids and intense plasma exchange

1983 • 50 citations

Vascular Endothelial Damage and Thrombosis1

2015 • 49 citations

Preliminary report: Treatment of the hemolytic-uremic syndrome with aspirin and dipyridamole

1975 • 49 citations

Haemolytic-uraemic syndrome: Epidemiological and clinical study

1974 • 49 citations

The Haemolytic Uraemic Syndrome—A Family Study

1975 • 48 citations

Thrombotic thrombocytopenic purpura with acute anuric renal failure

1966 • 47 citations

Fibrinogen deposition in acute renal failure.

1966 • 47 citations

Vitamin E treatment of haemolytic uraemic syndrome.

1984 • 47 citations

Streptokinase and anti-thrombotic therapy in the hemolytic-uremic syndrome

1974 • 46 citations

Familial deficiency of prostacyclin production stimulating factor in the hemolytic uremic syndrome of childhood

1981 • 45 citations

SERUM-COMPLEMENT LEVELS IN HÆMOLYTIC-URÆMIC SYNDROME

1973 • 45 citations

Renal homotransplantation in infants and children with the hemolytic-uremic syndrome.

1972 • 45 citations

The Endothelium and Thrombosis

1980 • 43 citations

Unilateral Shwartzman reaction: Cortical necrosis in one kidney following in vivo perfusion with endotoxin

1977 • 42 citations

The Hemolytic-Uremic Syndrome

1978 • 41 citations

Manipulation of the local thromboxane and prostacyclin balance in vivo by the antithrombotic compounds dazoxiben, acetylsalicylic acid and nafazatrom

1983 • 40 citations

Mesangial involvement in hemolytic-uremic syndrome. A light and electron microscopic study.

1976 • 40 citations

Reciprocal regulation of human platelet cAMP levels by thromboxane A2 and prostacyclin.

1978 • 39 citations

Disturbances of prostacyclin metabolism in children with hemolytic-uremic syndrome and in first degree relatives.

1986 • 37 citations

The treatment of the hemolytic-uremic syndrome with inhibitors of platelet function

1979 • 37 citations

Yersinia pseudotuberculosis Septicemia

1979 • 37 citations

Recurrence of the hemolytic uremic syndrome in a 3 1/2-year-old child, 4 months after second renal transplantation.

1978 • 36 citations

Abnormal prostacyclin metabolism in the hemolytic uremic syndrome: equivocal effect of prostacyclin infusions.

1982 • 34 citations

RED-BLOOD-CELL FRAGMENTATION IN MICROANGIOPATHIC HÆMOLYTIC ANÆMIA: IN-VITRO STUDIES

1967 • 34 citations

Hemolytic uremic syndrome with hypocomplementemia and deposits of IgM and C3 in the involved renal tissue.

1981 • 33 citations

Management of treatment failures in thrombotic thrombocytopenic purpura

1986 • 32 citations

Thrombotic thrombocytopenic purpura: Recovery after splenectomy associated with persistence of abnormally large von willebrand factor multimers

1985 • 31 citations

Fatal Late Postpartum Intravascular Coagulation with Acute Renal Failure

1969 • 30 citations

Platelet aggregating factor in the epidemic form of hemolytic-uremic syndrome in childhood.

1985 • 30 citations

Prostacyclin infusion in haemolytic-uraemic syndrome of children.

1981 • 29 citations

Treatment of Thrombotic Thrombocytopenic Purpura

1986 • 29 citations

Case Report: Von Willebrand Factor Abnormalities and Endothelial Cell Perturbation in a Patient with Acute Thrombotic Thrombocytopenic Purpura

1986 • 29 citations

Thrombotic Thrombocytopenic Purpura

1968 • 28 citations

Partial isolation and function of the prostacyclin regulating plasma factor

1985 • 28 citations

The Hemolytic Uremic Syndrome

1970 • 27 citations

Contribution of the subendothelium to prostacyclin release after vascular injury.

1982 • 27 citations

Prostanoids in hemolytic uremic syndrome

1985 • 26 citations

Plasmapheresis and Antiplatelet Agents in the Treatment of the Hemolytic Uremic Syndrome Secondary to Mitomycin

1986 • 25 citations

Abnormal Platelet and Vascular Prostaglandin Synthesis in an Infant with Hemolytic Uremic Syndrome

1983 • 25 citations

Treatment of Postpartum Hemolytic Uremic Syndrome With Plasma Exchange

1982 • 22 citations

PGI2-specific antibodies administered suggest against a role for endogenous PGI2 as a circulating vasodepressor hormone in the normotensive and spontaneously hypertensive rat

1980 • 21 citations

Thrombotic Thrombocytopenic Purpura: An Extended Editorial

2008 • 20 citations

The Hemolytic-Uremic Syndrome: Recovery After Treatment with Vincristine

1983 • 19 citations

Reversible deficient prostacyclin release in childhood hemolytic uremic syndrome.

1982 • 19 citations

SERUM-COMPLEMENT LEVELS IN HÆMOLYTIC-URÆMIC SYNDROME

1974 • 19 citations

Ineffective Epoprostenol Therapy for Thrombotic Thrombocytopenic Purpura

1983 • 16 citations

Observations on the Mechanism of the Haematological Changes in the Haemolytic Uraemic Syndrome of Infancy

1972 • 15 citations

HEMOLYTIC UREMIC SYNDROME Results of Treatment with Hemodialysis

1977 • 15 citations

Renal homotransplantation in infants and children with the hemolytic-uremic syndrome

1972 • 15 citations

An evaluation of treatment with heparin in the haemolytic-uraemic syndrome successfully treated by peritoneal dialysis.

1980 • 13 citations

Case 15-1986

1986 • 13 citations

Fibrinolytic Components of Cultured Endothelial Cells

1982 • 12 citations

Acute renal failure and intravascular coagulation.

1974 • 11 citations

In vitro prostacyclin production in the hemolytic-uremic syndrome.

1986 • 11 citations

Haemolytic-uraemic syndrome with renal failure: the effect of plasmapheresis.

1985 • 8 citations

The use of heparin in childhood hemolytic-uremic syndrome

1980 • 7 citations

Treatment of Adult Hemolytic Uremic Syndrome

1976 • 7 citations

[Thrombotic thrombocytopenic purpura treated with prostacyclin. Apropos of 2 case reports].

1986 • 6 citations

Plasma exchange as intensive therapy in thrombotic thrombocytopenic purpura.

1985 • 5 citations

Late streptokinase therapy in thrombotic microangiopathy: a case study.

1975 • 5 citations

6-keto-PGF1 alpha levels and prostacyclin therapy in 2 adult patients with hemolytic-uremic syndrome.

1986 • 5 citations

Impaired and exhausted platelets in modified generalized Shwartzman reaction: an analogue of hemolytic uremic syndrome associated with endotoxemia.

1983 • 4 citations

Thrombotic thrombocytopenic purpura (TTP) treatment: Italian cooperative retrospective study on 29 cases.

1986 • 3 citations

Deleted Work

1955 • 0 citations

Cited By (0)

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