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PGI2-specific antibodies administered suggest against a role for endogenous PGI2 as a circulating vasodepressor hormone in the normotensive and spontaneously hypertensive rat

Data up to Jan 2025

Published1980
Citations21
References17

Total Citations Per Year

Abstract

References (17)

Prostaglandins: Their Disappearance from and Release into the Circulation

1967 • 898 citations

Prostacyclin is a circulating hormone

1978 • 380 citations

Generation of prostacyclin by lungs in vivo and its release into the arterial circulation

1978 • 374 citations

COMPARISON OF THE VASODEPRESSOR EFFECTS OF PROSTACYCLIN AND 6‐OXO‐PROSTAGLANDIN F WITH THOSE OF PROSTAGLANDIN E2 IN RATS AND RABBITS

1978 • 277 citations

RECIRCULATION OF PROSTACYCLIN (PGI2) IN THE DOG

1978 • 167 citations

Enhanced formation of PGI2, a potent hypotensive substance, by aortic rings and homogenates of the spontaneously hypertensive rat

1978 • 142 citations

Distribution of prostaglandin biosynthetic pathways in several rat tissues. Formation of 6-ketoprostaglandin F1α

1977 • 127 citations

Diagnosis of Renovascular Hypertension

1964 • 119 citations

Is prostacyclin a physiologically important circulating anti-platelet agent?

1980 • 88 citations

Prostacyclin as a circulatory hormone

1979 • 76 citations

Antibodies which antagonise the effects of prostacyclin

1978 • 70 citations

Prostaglandin I2 has more potent hypotensive properties than prostaglandin E2 in the normal and spontaneously hypertensive rat

1978 • 65 citations

PRODUCTION OF 6-OXO-PGF1α BY HUMAN LUNG IN VIVO

1979 • 62 citations

Simple efficient synthesis of prostacyclin (PGI2)1

1977 • 54 citations

The use of immobilized ligands and [125I] protein a for immunoassays of thromboxane B2, prostaglandin D2, 13,14-dihydro-prostaglandin E2, 5,6-dihydro-prostaglandin I2, 6-keto-prostaglandin F1α, 15-hydroxy-9α,11α(epoxymethano)prosta5, 13-dienoic acid and 15-hydroxy-11α,9α(epoxymethano)prosta-5,13-dienoic acid

1979 • 48 citations

Distribution of prostaglandin biosynthetic pathways in organs and tissues of the fetal lamb

1978 • 34 citations

Comparison between the in vivo rate of metabolism of prostaglandin I2 and its blood-pressure-lowering response after intravenous administration in the rat

1979 • 10 citations

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PGI2-specific antibodies administered suggest against a role for endogenous PGI2 as a… (1980) – Prostaglandins | Metascience Observatory Explorer