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Difference between R5020 and the antiprogestin RU486 in antiproliferative effects on human breast cancer cells

Data up to Jan 2025

Published1987
Citations61
References33

Total Citations Per Year

Abstract

References (33)

A Human Cell Line From a Pleural Effusion Derived From a Breast Carcinoma 2

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A secreted glycoprotein induced by estrogen in human breast cancer cell lines

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RU 38486: Potent antiglucocorticoid activity correlated with strong binding to the cytosolic glucocorticoid receptor followed by an impaired activation

1984 • 372 citations

Induction of Epidermal Growth Factor-Related Polypeptides by 17β-Estradiol in MCF-7 Human Breast Cancer Cells

1986 • 296 citations

Autocrine Growth Stimulation of the MCF 7 Breast Cancer Cells by the Estrogen-Regulated 52 K Protein*

1986 • 273 citations

Estrogens Stimulate Cell Proliferation and Induce Secretory Proteins in a Human Breast Cancer Cell Line (T47D)*

1982 • 175 citations

Antiestrogenic Effect of R5020, a Synthetic Progestin in Human Breast Cancer Cells in Culture*

1983 • 173 citations

Steroid receptor-mediated cytotoxicity of an antiestrogen and an antiprogestin in breast cancer cells.

1987 • 172 citations

EFFECTS OF PROGESTINS ON ESTRADIOL RECEPTOR LEVELS IN HUMAN ENDOMETRIUM

1975 • 163 citations

[The effects of an antiprogesterone steroid in women: interruption of the menstrual cycle and of early pregnancy].

1982 • 150 citations

RU486, A Progestin and Glucocorticoid Antagonist, Inhibits the Growth of Breast Cancer Cells via the Progesterone Receptor*

1985 • 147 citations

Progestin Action and Progesterone Receptor Structure in Human Breast Cancer: A Review

1985 • 136 citations

The Antiprogestin RU38 486: Receptor-Mediated ProgestinVersusAntiprogestin Actions Screened in Estrogen-Insensitive T47DCOHuman Breast Cancer Cells*

1985 • 129 citations

Differences between oestrogen receptor activation by oestrogen and antioestrogen

1981 • 109 citations

Progestin effects on growth in the human breast cancer cell line T-47D—Possible therapeutic implications

1987 • 98 citations

Characterization of monoclonal antibodies to the estrogen-regulated Mr 52,000 glycoprotein and their use in MCF7 cells.

1985 • 89 citations

Dual effects of the progestin R5020 on proteins released by the T47D human breast cancer cells.

1984 • 75 citations

Reversal of the antitumor effects of tamoxifen by progesterone in the 7,12-dimethylbenzanthracene-induced rat mammary carcinoma model.

1987 • 74 citations

The antiproliferative effect of tamoxifen in breast cancer cells: mediation by the estrogen receptor

1984 • 71 citations

Oral contraceptives and breast cancer. In vitro effect of contraceptive steroids on human mammary cell growth

1987 • 57 citations

Actions of a progestogen on human breast cancer cells: Mechanisms of growth stimulation and inhibition

1987 • 55 citations

Processing and Estrogen Regulation of the 52-Kilodalton Protein inside MCF7Breast Cancer Cells*

1986 • 55 citations

Effects of progestins on growth of experimental breast cancer in culture: interaction with estradiol and prolactin and involvement of the polyamine pathway.

1987 • 44 citations

Antiprogestin-receptor complexes: Differences in the interaction of the antiprogestin RU38,486 and the progestin R5020 with the progesterone receptor of human breast cancer cells

1986 • 31 citations

Progesterone-specific stimulation of triglyceride biosynthesis in a breast cancer cell line (T-47D).

1983 • 31 citations

Steroidal and non steroidal antiestrogens in breast cancer cells in culture

1984 • 27 citations

A Role for Progesterone in Breast Cancer*

1977 • 21 citations

Progestin-specific markers in human cell lines: biological and pharmacological applications

1984 • 20 citations

Deleted Work

1955 • 0 citations

Cited By (0)

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Difference between R5020 and the antiprogestin RU486 in antiproliferative effects on… (1987) – Breast Cancer Research and Treatment | Metascience Observatory Explorer