Back to search

RU486, A Progestin and Glucocorticoid Antagonist, Inhibits the Growth of Breast Cancer Cells via the Progesterone Receptor*

Data up to Jan 2025

Published1985
Citations147
References28
Clinical Trials (1)

Total Citations Per Year

Abstract

References (28)

High resolution two-dimensional electrophoresis of proteins.

1975 • 19,515 citations

A Human Cell Line From a Pleural Effusion Derived From a Breast Carcinoma 2

1973 • 2,431 citations

The Fluorometric Measurement of Deoxyribonucleic Acid in Animal Tissues with Special Reference to the Central Nervous System

1958 • 1,786 citations

Breast Tumor Cell Lines From Pleural Effusions2

1974 • 973 citations

The effects of estrogens and antiestrogens on hormone-responsive human breast cancer in long-term tissue culture.

1976 • 820 citations

Establishment and characterization of a cell line of human breast carcinoma origin

1979 • 653 citations

A secreted glycoprotein induced by estrogen in human breast cancer cell lines

1980 • 481 citations

Estrogen Control of Progesterone Receptor in Human Breast Cancer: Role of Estradiol and Antiestrogen*

1978 • 407 citations

RU 38486: Potent antiglucocorticoid activity correlated with strong binding to the cytosolic glucocorticoid receptor followed by an impaired activation

1984 • 372 citations

Epithelioid and fibroblastic rat kidney cell clones: Epidermal growth factor (EGF) receptors and the effect of mouse sarcoma virus transformation

1978 • 296 citations

Cultivation of Human Breast Carcinomas<xref ref-type="fn" rid="FN1">2</xref>

1958 • 277 citations

Variant T47D human breast cancer cells with high progesterone-receptor levels despite estrogen and antiestrogen resistance

1982 • 249 citations

RU 486: a steroid with antiglucocorticosteroid activity that only disinhibits the human pituitary-adrenal system at a specific time of day.

1984 • 216 citations

Effects of Plasma Estrogen Sulfates in Mammary Cancer Cells*

1980 • 178 citations

Estrogens Stimulate Cell Proliferation and Induce Secretory Proteins in a Human Breast Cancer Cell Line (T47D)*

1982 • 175 citations

Antiestrogenic Effect of R5020, a Synthetic Progestin in Human Breast Cancer Cells in Culture*

1983 • 173 citations

Effect of Steroids on Growth of Mouse Fibroblastsin Vitro

1965 • 137 citations

Inhibition of glucocorticosteroid action in cultured L-929 mouse fibroblasts by RU 486, a new anti-glucocorticosteroid of high affinity for the glucocorticosteroid receptor

1983 • 125 citations

Characterization and quantitation of antiestrogen binding sites in estrogen receptor-positive and -negative human breast cancer cell lines.

1983 • 120 citations

Differences between oestrogen receptor activation by oestrogen and antioestrogen

1981 • 109 citations

The estrogenic and antiestrogenic activities of androgens in female target tissues

1983 • 105 citations

Dual effects of the progestin R5020 on proteins released by the T47D human breast cancer cells.

1984 • 75 citations

The antiproliferative effect of tamoxifen in breast cancer cells: mediation by the estrogen receptor

1984 • 71 citations

Progesterone receptors in human breast cancer. Stoichiometric translocation and nuclear receptor processing.

1983 • 55 citations

Antiglucocorticoid properties of RU 38486 in a differentiated hepatoma cell line

1983 • 38 citations

A 250-kilodalton cellular protein is induced by progestins in two human breast cancer cell lines MCF7 and T47D

1984 • 36 citations

Steroidal and non steroidal antiestrogens in breast cancer cells in culture

1984 • 27 citations

319 Progestins, antiprogestins and progesterone receptors in breast cancer: Mechanisms and biological actions

1983 • 4 citations

Cited By (0)

Loading...
RU486, A Progestin and Glucocorticoid Antagonist, Inhibits the Growth of Breast Cancer… (1985) – The Journal of Clinical Endocrinology & Metabolism | Metascience Observatory Explorer