HIV‐1 down‐regulates the expression of CD1d via Nef

CD1: Antigen Presentation and T Cell Function

2004 • 1,025 citations

The Selective Downregulation of Class I Major Histocompatibility Complex Proteins by HIV-1 Protects HIV-Infected Cells from NK Cells

1999 • 870 citations

CD1d-mediated Recognition of an α-Galactosylceramide by Natural Killer T Cells Is Highly Conserved through Mammalian Evolution

1998 • 649 citations

Crystal Structure of Mouse CD1: An MHC-Like Fold with a Large Hydrophobic Binding Groove

1997 • 629 citations

Structure–function relationships in HIV‐1 Nef

2001 • 356 citations

HIV-1 Nef protein binds to the cellular protein PACS-1 to downregulate class I major histocompatibility complexes

2000 • 301 citations

HIV-1 Nef Downregulates MHC-I by a PACS-1- and PI3K-Regulated ARF6 Endocytic Pathway

2002 • 297 citations

HIV-1 Nef impairs MHC class II antigen presentation and surface expression

2001 • 262 citations

The plasma membrane as a combat zone in the HIV battlefield

2000 • 248 citations

Diverse TCRs Recognize Murine CD1

1999 • 206 citations

Intracellular pathways of CD1 antigen presentation

2003 • 192 citations

Nef increases the synthesis of and transports cholesterol to lipid rafts and HIV-1 progeny virions

2003 • 172 citations

T-Cell Responses to CD1-Presented Lipid Antigens in Humans with Mycobacterium tuberculosis Infection

2003 • 159 citations

The HIV-1 Nef Protein Acts as a Connector with Sorting Pathways in the Golgi and at the Plasma Membrane

1997 • 158 citations

The N-Terminus of Nef from HIV-1/SIV Associates with a Protein Complex Containing Lck and a Serine Kinase

1997 • 156 citations

Vα24-JαQ-Independent, CD1d-Restricted Recognition of α-Galactosylceramide by Human CD4+ and CD8αβ+ T Lymphocytes

2002 • 153 citations

Intravenous Injection of a Lentiviral Vector Encoding NY-ESO-1 Induces an Effective CTL Response

2004 • 110 citations

HIV-1 Nef Blocks Transport of MHC Class I Molecules to the Cell Surface Via a PI 3-Kinase-Dependent Pathway

2001 • 105 citations

Nef-Mediated Disruption of HLA-A2 Transport to the Cell Surface in T Cells

2003 • 89 citations

Human immunodeficiency virus and host cell lipids. Interesting pathways in research for a new HIV therapy

2002 • 84 citations

Requirement of the Proteasome for the Trimming of Signal Peptide-derived Epitopes Presented by the Nonclassical Major Histocompatibility Complex Class I Molecule HLA-E

2003 • 63 citations

Induction of activator protein 1 (AP-1) in macrophages by human immunodeficiency virus type-1 NEF is a cell-type-specific response that requires both Hck and MAPK signaling events 1 1Edited by J. Karn

1999 • 63 citations