Oligomerization of NTRC at the glnA enhancer is required for transcriptional activation.

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Rapid and efficient site-specific mutagenesis without phenotypic selection.

1985 • 7,573 citations

Construction and characterization of amplifiable multicopy DNA cloning vehicles derived from the P15A cryptic miniplasmid

1978 • 4,472 citations

Escherichia Coli and Salmonella: Typhimurium Cellular and Molecular Biology

1987 • 4,385 citations

Equilibria and kinetics of lac repressor-operator interactions by polyacrylamide gel electrophoresis

1981 • 2,828 citations

DNAase footprinting a simple method for the detection of protein-DNA binding specificity

1978 • 2,092 citations

A gel electrophoresis method for quantifying the binding of proteins to specific DNA regions: application to components of the Escherichia coli lactose operon regulatory system

1981 • 1,991 citations

Analysis of Sp1 in vivo reveals mutiple transcriptional domains, including a novel glutamine-rich activation motif

1988 • 1,403 citations

Single-stranded DNA ‘blue’ T7 promoter plasmids: a versatile tandem promoter system for cloning and protein engineering

1986 • 816 citations

OPTIMIZATION OF PCRs

1990 • 632 citations

Covalent modification of the glnG product, NRI, by the glnL product, NRII, regulates the transcription of the glnALG operon in Escherichia coli.

1986 • 565 citations

Synergistic activation by the glutamine-rich domains of human transcription factor Sp1

1989 • 539 citations

Expression of sigma 54 (ntrA)-dependent genes is probably united by a common mechanism

1989 • 504 citations

Transcription of glnA in E. coli is stimulated by activator bound to sites far from the promoter

1986 • 444 citations

Function of a Bacterial Activator Protein That Binds to Transcriptional Enhancers

1989 • 440 citations

Different activation domains of Sp1 govern formation of multimers and mediate transcriptional synergism.

1991 • 437 citations

The nucleotide sequence of pACYC184

1988 • 407 citations

A mechanism for synergistic activation of a mammalian gene by GAL4 derivatives

1990 • 386 citations

Protein kinase and phosphoprotein phosphatase activities of nitrogen regulatory proteins NTRB and NTRC of enteric bacteria: roles of the conserved amino-terminal domain of NTRC.

1988 • 365 citations

Products of nitrogen regulatory genes ntrA and ntrC of enteric bacteria activate glnA transcription in vitro: evidence that the ntrA product is a sigma factor.

1985 • 352 citations

The phosphorylated form of the enhancer-binding protein NTRC has an ATPase activity that is essential for activation of transcription

1991 • 315 citations

Cooperative binding of steroid hormone receptors contributes to transcriptional synergism at target enhancer elements

1989 • 270 citations

Studies on the selectivity of DNA precipitation by spermine

1981 • 267 citations

How different eukaryotic transcriptional activators can cooperate promiscuously

1990 • 261 citations

DNA-looping and enhancer activity: association between DNA-bound NtrC activator and RNA polymerase at the bacterial glnA promoter.

1990 • 260 citations

Initiation of transcription at the bacterial glnAp2 promoter by purified E. coli components is facilitated by enhancers

1987 • 254 citations

Phosphorylation of nitrogen regulator I (NRI) of Escherichia coli.

1988 • 251 citations

Probing the Escherichia coli glnALG upstream activation mechanism in vivo.

1988 • 233 citations

An enhancer stimulates transcription in Trans when attached to the promoter via a protein bridge

1989 • 202 citations

Synergism in transcriptional activation: a kinetic view.

1993 • 196 citations

A Bacterial Enhancer Functions to Tether a Transcriptional Activator Near a Promoter

1990 • 190 citations

Glutamate at the Site of Phosphorylation of Nitrogen-regulatory Protein NTRC Mimics Aspartyl-Phosphate and Activates the Protein

1993 • 175 citations

The ?24/?12 promoter comes of age

1989 • 172 citations

The prokaryotic enhancer binding protein NTRC has an ATPase activity which is phosphorylation and DNA dependent.

1992 • 157 citations

Use of polylysine for adsorption of nuclei acids and enzymes to electron microscope specimen films.

1977 • 153 citations

Phosphorylation of nitrogen regulator I of Escherichia coli induces strong cooperative binding to DNA essential for activation of transcription.

1992 • 145 citations

Role of integration host factor in the regulation of the glnHp2 promoter of Escherichia coli.

1991 • 140 citations

The function of isolated domains and chimaeric proteins constructed from the transcriptional activators NifA and NtrC of Klebsiella pneumoniae

1990 • 110 citations

Role of integration host factor in stimulating transcription from the σ54-dependent nifH promoter

1992 • 109 citations

Transactivation of the Xenopus rRNA gene promoter by its enhancer

1989 • 108 citations

Isolation of the nitrogen assimilation regulator NR _I , the product of the glnG gene of Escherichia coli

1983 • 104 citations

Unscrambling the puzzle of biological machines: The importance of the details

1992 • 103 citations

Phosphorylation site of NtrC, a protein phosphatase whose covalent intermediate activates transcription

1992 • 98 citations

Transcriptional synergy by the Epstein-Barr virus transactivator ZEBRA

1992 • 92 citations

Co-operative interactions between the catabolite gene activator protein and the lac repressor at the lactose promoter

1990 • 78 citations

Activation of glnA transcription by nitrogen regulator I (NRI)-phosphate in Escherichia coli: evidence for a long-range physical interaction between NRI-phosphate and RNA polymerase

1989 • 73 citations

The role of activator binding sites in transcriptional control of the divergently transcribed nifF and nif LA promoters from Klebsiella pneumoniae

1988 • 70 citations

Purification of the alternative sigma factor, sigma 54, from Salmonella typhimurium and characterization of sigma 54-holoenzyme.

1991 • 64 citations

The effect on the function of the transcriptional activator NtrC fromKlebsiella pneumoniaeof mutations in the DNA-recognition helix

1988 • 60 citations

[12] Analysis of DNA-protein interactions by affinity coelectrophoresis

1991 • 54 citations

In vitro transcription of the nitrogen fixation regulatory operon nifLA of Klebsiella pneumoniae

1987 • 51 citations

Gene regulation from sites near and far.

1989 • 17 citations

The binding of cyclic AMP receptor protein to two lactose promoter sites is not cooperative in vitro

1991 • 15 citations

DNase I FOOTPRINTING

1990 • 11 citations