Adenosine triphosphate-dependent transport of estradiol-17?(?-d-glucuronide) in membrane vesicles by MDR1 expressed in insect cells

BIOCHEMISTRY OF MULTIDRUG RESISTANCE MEDIATED BY THE MULTIDRUG TRANSPORTER

1993 • 3,515 citations

Expression of the human multidrug resistance cDNA in insect cells generates a high activity drug-stimulated membrane ATPase.

1992 • 629 citations

Transport of glutathione, glucuronate, and sulfate conjugates by the MRP gene-encoded conjugate export pump.

1996 • 569 citations

A mutation in the human canalicular multispecific organic anion transporter gene causes the Dubin-Johnson syndrome

1997 • 551 citations

The rat canalicular conjugate export pump (Mrp2) is down-regulated in intrahepatic and obstructive cholestasis

1997 • 502 citations

The P-Glycoprotein Efflux Pump: How Does it Transport Drugs?

1997 • 449 citations

Molecular aspects of hepatobiliary transport

1997 • 304 citations

ATP-dependent transport of bilirubin glucuronides by the multidrug resistance protein MRP1 and its hepatocyte canalicular isoform MRP2

1997 • 300 citations

ATP-dependent 17β-Estradiol 17-(β-D-Glucuronide) Transport by Multidrug Resistance Protein (MRP)

1996 • 265 citations

Transport of glutathione conjugates and glucuronides by the multidrug resistance proteins MRP1 and MRP2.

1997 • 260 citations

Functional reconstitution of drug transport and ATPase activity in proteoliposomes containing partially purified P-glycoprotein.

1993 • 257 citations

P-Glycoprotein Substrates and Antagonists Cluster into Two Distinct Groups

1997 • 229 citations

ATP/Mg2+-dependent binding of vincristine to the plasma membrane of multidrug-resistant K562 cells.

1988 • 143 citations

Induction of multidrug resistance gene expression during cholestasis in rats and nonhuman primates

1993 • 101 citations

Pregnancy, Oral Contraceptives, and Chronic Familial Jaundice with Predominantly Conjugated Hyperbilirubinemia (Dubin-Johnson Syndrome)

1972 • 93 citations

Expression of the multidrug resistance genes in the liver

1997 • 73 citations

Mutation of Glycine 185 to Valine Alters the ATPase Function of the Human P-glycoprotein Expressed in Sf9 Cells

1995 • 62 citations

Cholestatic Properties and Hepatic Transport of Steroid Glucuronides

1997 • 53 citations

17 beta-estradiol glucuronide: an inducer of cholestasis and a physiological substrate for the multidrug resistance transporter.

1993 • 39 citations

Steroid D-ring glucuronides: a new class of cholestatic agents

1985 • 32 citations

MDR1 substrates/modulators protect against beta-estradiol-17beta-D-glucuronide cholestasis in rat liver.

1996 • 31 citations

Estradiol-17β-glucuronide-induced cholestasis

1993 • 30 citations

ATP-dependent transport of beta-estradiol 17-(beta-D-glucuronide) in rat canalicular membrane vesicles

1996 • 24 citations