Mutation of Glycine 185 to Valine Alters the ATPase Function of the Human P-glycoprotein Expressed in Sf9 Cells

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Molecular cloning: A laboratory manual

1990 • 85,659 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

ABC Transporters: From Microorganisms to Man

1992 • 3,956 citations

Assay of proteins in the presence of interfering materials

1976 • 3,217 citations

A Manual of Methods for Baculovirus Vectors and Insect Cell Culture Procedures.

1987 • 1,703 citations

Expression of the human multidrug resistance cDNA in insect cells generates a high activity drug-stimulated membrane ATPase.

1992 • 629 citations

Fluorescent cellular indicators are extruded by the multidrug resistance protein.

1993 • 496 citations

An altered pattern of cross-resistance in multidrug-resistant human cells results from spontaneous mutations in the mdr1 (P-glycoprotein) gene

1988 • 430 citations

Detection of P-glycoprotein isoforms by gene-specific monoclonal antibodies.

1990 • 386 citations

Membrane vesicles from multidrug-resistant human cancer cells contain a specific 150- to 170-kDa protein detected by photoaffinity labeling.

1986 • 342 citations

ATPase activity of purified and reconstituted P-glycoprotein from Chinese hamster ovary cells.

1994 • 235 citations

Characterization of the adenosine triphosphatase activity of Chinese hamster P-glycoprotein.

1993 • 220 citations

Functional consequences of proline mutations in the predicted transmembrane domain of P-glycoprotein.

1993 • 218 citations

Characterization of the azidopine and vinblastine binding site of P-glycoprotein.

1992 • 217 citations

Multidrug Resistance

1991 • 207 citations

Photoaffinity labeling of the multidrug-resistance-related P-glycoprotein with photoactive analogs of verapamil.

1988 • 205 citations

Two different regions of Phosphoglycoprotein are photoaffinity-labeled by azidopine

1989 • 196 citations

P-Glycoprotein gene (MDR1) cDNA from human adrenal: Normal P-glycoprotein carries Gly185 with an altered pattern of multidrug resistance

1989 • 179 citations

ATPase activity of partially purified P-glycoprotein from multidrug-resistant Chinese hamster ovary cells

1992 • 147 citations

Molecular basis of preferential resistance to colchicine in multidrug-resistant human cells conferred by Gly-185----Val-185 substitution in P-glycoprotein.

1990 • 143 citations

Covalent inhibitors of P-glycoprotein ATPase activity.

1994 • 139 citations

Expression of the human multidrug transporter in insect cells by a recombinant baculovirus

1990 • 119 citations

Antiestrogens and steroid hormones: Substrates of the human P-glycoprotein

1994 • 115 citations

Monomer of sodium and potassium ion activated adenosine triphosphatase displays complete enzymic function

1982 • 85 citations

Direct demonstration of high affinity interactions of immunosuppressant drugs with the drug binding site of the human P-glycoprotein.

1994 • 80 citations

Photoaffinity labeling of P-glycoprotein in multidrug resistant cells with photoactive analogs of colchicine

1989 • 65 citations

Structurally Distinct MDR Modulators Show Specific Patterns of Reversal Against P-Glycoproteins Bearing Unique Mutations at Serine939/941

1994 • 49 citations

Direct demonstration of structural changes in soluble, monomeric Ca2+-ATPase associated with Ca2+ release during the transport cycle.

1985 • 46 citations

Equilibrium, kinetic and photoaffinity labeling studies of daunomycin binding to P‐glycoprotein‐containing membranes of multidrug‐resistant Chinese hamster ovary cells

1989 • 39 citations

Monomeric solubilized sarcoplasmic reticulum Ca pump protein: demonstration of Ca binding and dissociation coupled to ATP hydrolysis.

1984 • 33 citations

High yield expression of the Neurospora crassa plasma membrane H(+)-ATPase in Saccharomyces cerevisiae

1994 • 22 citations