Degradation from the endoplasmic reticulum: Disposing of newly synthesized proteins

ASSEMBLY OF ASPARAGINE-LINKED OLIGOSACCHARIDES

1985 • 4,790 citations

3-Methyladenine: Specific inhibitor of autophagic/lysosomal protein degradation in isolated rat hepatocytes

1982 • 1,313 citations

Posttranslational association of immunoglobulin heavy chain binding protein with nascent heavy chains in nonsecreting and secreting hybridomas.

1986 • 896 citations

Perturbation of vesicular traffic with the carboxylic ionophore monensin

1983 • 890 citations

Expression of wild-type and mutant forms of influenza hemagglutinin: The role of folding in intracellular transport

1986 • 879 citations

Purification and Properties of an Endo-β-N-acetylglucosaminidase from Streptomyces griseus

1974 • 870 citations

Effects of sodium butyrate, a new pharmacological agent, on cells in culture

1981 • 808 citations

Effect of weak bases on the intralysosomal pH in mouse peritoneal macrophages.

1981 • 736 citations

Low temperature selectively inhibits fusion between pinocytic vesicles and lysosomes during heterophagy of 125I-asialofetuin by the perfused rat liver.

1980 • 451 citations

Antibodies to the Golgi complex and the rough endoplasmic reticulum.

1982 • 418 citations

Oligomerization is essential for transport of vesicular stomatitis viral glycoprotein to the cell surface

1986 • 417 citations

Assembly of influenza hemagglutinin trimers and its role in intracellular transport.

1986 • 413 citations

The sodium channel from rat brain. Purification and subunit composition.

1984 • 352 citations

Failure to synthesize the T Cell CD3-? chain: Structure and function of a partial T cell receptor complex

1988 • 351 citations

Acidification of the cytosol inhibits endocytosis from coated pits.

1987 • 345 citations

Identification of the components of the murine T cell antigen receptor complex

1985 • 333 citations

[59] Inhibitors of lysosomal function

1983 • 331 citations

Monoclonal antibodies against the antigen receptor on a cloned T-cell hybrid.

1983 • 293 citations

Native disulphide bond formation in protein biosynthesis: evidence for the role of protein disulphide isomerase

1984 • 293 citations

EXTRALYSOSOMAL PROTEIN DEGRADATION

1986 • 279 citations

Leupeptin, a Protease Inhibitor, Decreases Protein Degradation in Normal and Diseased Muscles

1978 • 267 citations

Altered cytoplasmic domains affect intracellular transport of the vesicular stomatitis virus glycoprotein

1983 • 264 citations

Temperature-sensitive steps in the transport of secretory proteins through the Golgi complex in exocrine pancreatic cells.

1986 • 251 citations

Specific antigen—la activation of transfected human T cells expressing murine Ti αβ —human T3 receptor complexes

1987 • 247 citations

Building a multichain receptor: synthesis, degradation, and assembly of the T-cell antigen receptor.

1987 • 232 citations

Developmentally regulated rearrangement and expression of genes encoding the T cell receptor-T3 complex

1986 • 210 citations

Assembly in vivo of mouse muscle acetylcholine receptor: Identification of an α subunit species that may be an assembly intermediate

1983 • 204 citations

Expression of genes of the T-cell antigen receptor complex in precursor thymocytes

1985 • 135 citations

Regulation of membrane IgM expression in secretory B cells: translational and post-translational events.

1987 • 125 citations

Effect of microtubular or translational inhibitors on general cell protein degradation. Evidence for a dual catabolic pathway

1977 • 110 citations

Expression of antigen-specific, major histocompatibility complex-restricted receptors by cortical and medullary thymocytes in situ

1985 • 106 citations

Cytochrome P-450 and NADPH-cytochrome P-450 reductase are degraded in the autolysosomes in rat liver [published erratum appears in J Cell Biol 1987 Jul;105(1):609]

1987 • 101 citations

Two integral membrane proteins located in the cis-middle and trans-part of the Golgi system acquire sialylated N-linked carbohydrates and display different turnovers and sensitivity to cAMP-dependent phosphorylation.

1987 • 100 citations

Acridine Orange as a Fluorescent Probe for Lysosomal Proton Pump1

1982 • 99 citations

Isolation and characterization of a cDNA clone encoding the murine homologue of the human 20K T3/T-cell receptor glycoprotein

1985 • 86 citations

Degradation of unassembled α- and β-spectrin by distinct intracellular pathways: Regulation of spectrin topogenesis by β-spectrin degradation

1985 • 70 citations

Characterization of an anti-peptide antibody that recognizes the murine analogue of the human T cell antigen receptor-T3 delta-chain.

1986 • 58 citations

Molecular cloning of the cDNA encoding the T3 gamma subunit of the mouse T3/T cell antigen receptor complex.

1987 • 57 citations

Effects of temperature on the degradation of proteins in rabbit reticulocyte lysates and after injection into HeLa cells.

1984 • 56 citations

Association and dissociation of the murine T cell receptor associated protein (TRAP). Early events in the biosynthesis of a multisubunit receptor.

1988 • 49 citations

Glucosidase II, a protein of the endoplasmic reticulum with high mannose oligosaccharide chains and a rapid turnover.

1987 • 47 citations

Intracellular disruption of rat heart lysosomes by leucine methyl ester: effects on protein degradation.

1981 • 39 citations

Thymocytes with the predicted properties of pre-T cells.

1987 • 19 citations

Characterization of the Antigen‐Specific T Cell Receptor from a Pigeon Cytochrome c‐Specific T Cell Hybrid

1984 • 18 citations