In vivo functional protein-protein interaction: nuclear targeted hsp90 shifts cytoplasmic steroid receptor mutants into the nucleus.

Protein folding in the cell

1992 • 4,138 citations

Two interdependent basic domains in nucleoplasmin nuclear targeting sequence: Identification of a class of bipartite nuclear targeting sequence

1991 • 1,501 citations

Two signals mediate hormone-dependent nuclear localization of the glucocorticoid receptor.

1987 • 999 citations

Reduced levels of hsp90 compromise steroid receptor action in vivo

1990 • 794 citations

Nuclear protein localization

1991 • 570 citations

The common 90-kd protein component of non-transformed ‘8S’ steroid receptors is a heat-shock protein.

1985 • 527 citations

Steroid receptors and their associated proteins.

1993 • 513 citations

Evidence that the 90-kDa phosphoprotein associated with the untransformed L-cell glucocorticoid receptor is a murine heat shock protein.

1985 • 492 citations

Common non-hormone binding component in non-transformed chick oviduct receptors of four steroid hormones

1984 • 442 citations

Mechanisms of nuclear localization of the progesterone receptor: Evidence for interaction between monomers

1989 • 329 citations

Cooperation of proto-signals for nuclear accumulation of estrogen and progesterone receptors.

1992 • 314 citations

A 90,000-dalton binding protein common to both steroid receptors and the Rous sarcoma virus transforming protein, pp60v-src.

1985 • 304 citations

Nucleocytoplasmic shuttling of the progesterone receptor.

1991 • 296 citations

A region in the steroid binding domain determines formation of the non-DNA-binding, 9 S glucocorticoid receptor complex.

1988 • 267 citations

Nucleoplasmin cDNA sequence reveals polyglutamic acid tracts and a cluster of sequences homologous to putative nuclear localization signals.

1987 • 263 citations

Hsp90 chaperonins possess ATPase activity and bind heat shock transcription factors and peptidyl prolyl isomerases.

1993 • 245 citations

Secondary structure prediction: combination of three different methods

1988 • 199 citations

An immunophilin that binds M(r) 90,000 heat shock protein: main structural features of a mammalian p59 protein.

1992 • 168 citations

Bidirectional transport of glucocorticoid receptors across the nuclear envelope.

1993 • 167 citations

Heat shock protein 90 as a critical factor in maintaining glucocorticosteroid receptor in a nonfunctional state.

1991 • 163 citations

Evidence for intracellular association of the glucocorticoid receptor with the 90-kDa heat shock protein.

1988 • 124 citations

Control of steroid receptor function and cytoplasmic‐nuclear transport by heat shock proteins

1992 • 100 citations

Hormonal regulation of the nuclear localization signals of the human glucocorticosteroid receptor

1992 • 80 citations

The cDNA-derived amino acid sequence of chick heat shock protein Mr 90,000 (HSP 90) reveals A “DNA like” structure: Potential site of interaction with steroid receptors

1989 • 64 citations

Chick heat-shock protein of Mr = 90,000, free or released from progesterone receptor, is in a dimeric form

1989 • 60 citations

Cloning of the chick hsp 90 cDNA in expression vector

1985 • 56 citations

The nonactivated progesterone receptor is a nuclear heterooligomer.

1990 • 47 citations

Interaction of glucocorticosteroid receptor and wild-type or mutated 90-kDa heat shock protein coexpressed in baculovirus-infected Sf9 cells.

1993 • 35 citations

Nuclear progesterone receptor is mainly heat shock protein 90-free in vivo.

1993 • 34 citations

Activation of Hormone and Growth Factor Receptors

1990 • 10 citations