Effects of inefficient cleavage of the signal sequence of HIV-1 gp 120 on its association with calnexin, folding, and intracellular transport.

Development of Virus-Like Particle Technology from Small Highly Symmetric to Large Complex Virus-Like Particle Structures

2013 • 5,819 citations

The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirus

1984 • 3,530 citations

T-lymphocyte T4 molecule behaves as the receptor for human retrovirus LAV

1984 • 2,441 citations

Synthetic peptide vaccine design: synthesis and properties of a high-density multiple antigenic peptide system.

1988 • 1,241 citations

Role of N-linked oligosaccharide recognition, glucose trimming, and calnexin in glycoprotein folding and quality control.

1994 • 815 citations

Association of folding intermediates of glycoproteins with calnexin during protein maturation

1993 • 558 citations

Biosynthesis, cleavage, and degradation of the human immunodeficiency virus 1 envelope glycoprotein gp160.

1988 • 442 citations

Neutralization of the AIDS Retrovirus by Antibodies to a Recombinant Envelope Glycoprotein

1986 • 362 citations

Regulation of MHC Class I Transport by the Molecular Chaperone, Calnexin (p88, IP90)

1994 • 351 citations

Folding, interaction with GRP78-BiP, assembly, and transport of the human immunodeficiency virus type 1 envelope protein

1991 • 333 citations

Mutation of the signal peptide-encoding region of the preproparathyroid hormone gene in familial isolated hypoparathyroidism.

1990 • 293 citations

A posttargeting signal sequence recognition event in the endoplasmic reticulum membrane

1995 • 278 citations

Endoplasmic reticulum resident protein of 90 kilodaltons associates with the T- and B-cell antigen receptors and major histocompatibility complex antigens during their assembly.

1992 • 259 citations

Cotranslational folding and calnexin binding during glycoprotein synthesis.

1995 • 248 citations

Retention of Unassembled Components of Integral Membrane Proteins by Calnexin

1994 • 243 citations

Efficient dissociation of the p88 chaperone from major histocompatibility complex class I molecules requires both beta 2-microglobulin and peptide.

1992 • 184 citations

Glycosylation is necessary for the correct folding of human immunodeficiency virus gp120 in CD4 binding

1993 • 178 citations

Failure of a human immunodeficiency virus (HIV) immune globulin to protect chimpanzees against experimental challenge with HIV.

1988 • 162 citations

Humoral immune response to the entire human immunodeficiency virus envelope glycoprotein made in insect cells.

1987 • 138 citations

Calreticulin Interacts with Newly Synthesized Human Immunodeficiency Virus Type 1 Envelope Glycoprotein, Suggesting a Chaperone Function Similar to That of Calnexin

1996 • 134 citations

Conformational Changes Induced in the Endoplasmic Reticulum Luminal Domain of Calnexin by Mg-ATP and Ca2+

1995 • 130 citations

Inefficient Membrane Targeting, Translocation, and Proteolytic Processing by Signal Peptidase of a Mutant Preproparathyroid Hormone Protein

1995 • 106 citations

Possible involvement of inefficient cleavage of preprovasopressin by signal peptidase as a cause for familial central diabetes insipidus.

1993 • 105 citations

A two-step recognition of signal sequences determines the translocation efficiency of proteins.

1996 • 99 citations

Model for intracellular folding of the human immunodeficiency virus type 1 gp120

1989 • 95 citations

Control of Expression, Glycosylation, and Secretion of HIV-1 gp120 by Homologous and Heterologous Signal Sequences

1994 • 94 citations

Regulated Expression Allows High Level Production and Secretion of HIV-1 gp120 Envelope Glycoprotein in Drosophila Schneider Cells

1991 • 91 citations

Expression of membrane-associated and secreted variants of gp160 of human immunodeficiency virus type 1 in vitro and in continuous cell lines

1988 • 84 citations

Increased cell surface expression and enhanced folding in the endoplasmic reticulum of a mutant erythropoietin receptor.

1995 • 80 citations

Synthesis and processing of human immunodeficiency virus type 1 envelope proteins encoded by a recombinant human adenovirus

1989 • 79 citations

Expression of envelope glycoproteins of human immunodeficiency virus by an insect virus vector

1987 • 69 citations

Human coagulation factor X deficiency caused by a mutant signal peptide that blocks cleavage by signal peptidase but not targeting and translocation to the endoplasmic reticulum.

1993 • 63 citations

Subcellular localization and targeting of cathepsin E.

1994 • 59 citations

Expression and characterization of a functional human immunodeficiency virus envelope glycoprotein in insect cells

1990 • 54 citations

Chimeric gag-V3 virus-like particles of human immunodeficiency virus induce virus-neutralizing antibodies.

1992 • 50 citations

Secretion of a Truncated Form of the Human Immunodeficiency Virus Type 1 Envelope Glycoprotein

1993 • 39 citations

The propeptide of beta-glucuronidase. Further evidence of its involvement in compartmentalization of beta-glucuronidase and sequence similarity with portions of the reactive site region of the serpin superfamily.

1990 • 20 citations

Regulated export of a secretory protein from the ER of the hepatocyte: a specific binding site retaining C-reactive protein within the ER is downregulated during the acute phase response.

1992 • 19 citations