Conformational isomerism of endothelin in acidic aqueous media: a quantitative NOESY analysis

<scp>CHARMM</scp>: A program for macromolecular energy, minimization, and dynamics calculations

1983 • 14,615 citations

A novel potent vasoconstrictor peptide produced by vascular endothelial cells

1988 • 10,786 citations

Application of phase sensitive two-dimensional correlated spectroscopy (COSY) for measurements of 1H-1H spin-spin coupling constants in proteins

1983 • 3,150 citations

A two-dimensional nuclear overhauser experiment with pure absorption phase in four quadrants

1982 • 2,567 citations

Turns in Peptides and Proteins

1985 • 1,658 citations

Pseudo-structures for the 20 common amino acids for use in studies of protein conformations by measurements of intramolecular proton-proton distance constraints with nuclear magnetic resonance

1983 • 1,012 citations

Determination of three‐dimensional structures of proteins from interproton distance data by hybrid distance geometry‐dynamical simulated annealing calculations

1988 • 775 citations

Folding of immunogenic peptide fragments of proteins in water solution

1988 • 735 citations

Molecular biology and biochemistry of the endothelins

1989 • 620 citations

Determination of the three-dimensional solution structure of the C-terminal domain of cellobiohydrolase I from Trichoderma reesei. A study using nuclear magnetic resonance and hybrid distance geometry-dynamical simulated annealing

1989 • 513 citations

Three-dimensional structure of interleukin 8 in solution

1990 • 441 citations

Folding of immunogenic peptide fragments of proteins in water solution

1988 • 437 citations

Prediction of the folding of short polypeptide segments by uniform conformational sampling

1987 • 428 citations

Sarafotoxin, a Novel Vasoconstrictor Peptide: Phosphoinositide Hydrolysis in Rat Heart and Brain

1988 • 362 citations

Fourier transform multiple quantum nuclear magnetic resonance

1978 • 329 citations

Three-dimensional structure of proteins determined by molecular dynamics with interproton distance restraints: application to crambin.

1986 • 322 citations

Origin of τ2 and τ2 ridges in 2D NMR spectra and procedures for suppression

1986 • 321 citations

High-resolution structure of an HIV zinc fingerlike domain via a new NMR-based distance geometry approach

1990 • 268 citations

Application of molecular dynamics with interproton distance restraints to three-dimensional protein structure determination

1986 • 252 citations

Determination of biomolecular structures from proton-proton NOE's using a relaxation matrix approach

1988 • 222 citations

Iterative procedure for structure determination from proton-proton NOEs using a full relaxation matrix approach. Application to a DNA octamer

1989 • 221 citations

Structure-activity relationships of endothelin: Importance of the C-terminal moiety

1988 • 220 citations

Automated stereospecific proton NMR assignments and their impact on the precision of protein structure determinations in solution

1989 • 212 citations

Stereospecific assignments of side‐chain protons and characterization of torsion angles in Eglin c

1987 • 187 citations

Conformation of recombinant desulfatohirudin in aqueous solution determined by nuclear magnetic resonance

1989 • 126 citations

Structure-activity relationship of endothelin: Importance of charged groups

1989 • 120 citations

Stereospecific assignments of ¹H‐nmr methyl lines and conformation of valyl residues in the lac repressor headpiece

1985 • 120 citations

Solution structure of apamin determined by nuclear magnetic resonance and distance geometry

1988 • 101 citations

¹H‐Nmr stereospecific assignments by conformational data‐base searches

1990 • 100 citations

Synthesis and disulfide structure determination of porcine endothelin: an endothelium‐derived vasoconstricting peptide

1988 • 89 citations

Three-Dimensional Solution Structure of Plastocyanin from the Green Alga Scenedesmus obliquus

1988 • 87 citations

Helix formation and stability in a signal sequence

1989 • 86 citations

Limited sampling of conformational space by the distance geometry algorithm: implications for structures generated from NMR data

1989 • 75 citations

Solution conformation of endothelin determined by means of ¹H-NMR spectroscopy and distance geometry calculations

1991 • 72 citations

Solution conformation of endothelin determined by nuclear magnetic resonance and distance geometry

1989 • 70 citations

Determining the structure of a glycopeptide Ac2-Lys-D-Ala-D-Ala complex using NMR parameters and molecular modeling

1986 • 65 citations

Skewed exchange spectroscopy. Two-dimensional method for the measurement of cross relaxation in proton NMR spectroscopy

1984 • 63 citations

¹H‐NMR study of endothelin, sequence‐specific assignment of the spectrum and a solution structure

1989 • 58 citations

Quantitative small molecule NOESY. A practical guide for derivation of cross‐relaxation rates and internuclear distances

1989 • 53 citations

Conformation of endothelin in aqueous ethylene glycol determined by¹H-NMR and molecular dynamics simulations

1991 • 50 citations

The conformation of endothelin-1 in aqueous solution: NMR-Derived constraints combined with distance geometry and molecular dynamics calculations

1991 • 46 citations

A method for evaluating correlation times for tumbling and internal motion in macromolecules using cross-relaxation rate constants from proton NMR spectra

1986 • 44 citations

Solution conformation of Endothelin‐1 by ¹H NMR, CD, and molecular modeling

1991 • 44 citations

Solution conformation of endothelin, a potent vaso‐constricting bicyclic peptide A combined use¹H NMR spectroscopy and distance geometry calculations

1991 • 40 citations

Determination of the structure of [Nle⁷]‐endothelin by ¹H NMR

1991 • 39 citations

Determination of Protein Structures in Solution Using Nmr Data and Impact

1988 • 35 citations

Conformation of sarafotoxin‐6b in aqueous solution determined by NMR spectroscopy and distance geometry

1991 • 34 citations

Structure-activity relationships of monocyclic endothelin analogs

1991 • 33 citations

Small molecule conformation in the receptor‐bound state by the two‐dimensional spin exchange experiment

1987 • 31 citations

Structure of biphenomycin A derived from two-dimensional NMR spectroscopy and molecular modeling

1989 • 27 citations

High-resolution NMR studies of fibrinogen-like peptides in solution: resonance assignments and conformational analysis of residues 1-23 of the A.alpha. chain of human fibrinogen

1988 • 27 citations

Evidence for aggregation of endothelin 1 in water

1990 • 26 citations

The conformation of apamin

1986 • 25 citations

Solution conformation of endothelin-3 by 1H NMR and distance geometry calculations

1991 • 25 citations

Structure‐activity relationship in vasoconstrictor effects of sarafotoxins andendothelin‐1

1990 • 22 citations

Proposed solution structure of endothelin

1990 • 17 citations

Fluorescence studies of endothelin-1

1991 • 16 citations

Conformation of a heptadecapeptide comprising the segment encephalitogenic in rhesus monkey

1988 • 16 citations

Computer simulation of transient NOE experiments with short preparatory delays

1987 • 13 citations

Temperature and field dependent 1H-NMR relaxation data as probes of prostaglandin motional parameters in aqueous media

1984 • 5 citations