Proposed solution structure of endothelin

A novel potent vasoconstrictor peptide produced by vascular endothelial cells

1988 • 10,786 citations

Analysis of the accuracy and implications of simple methods for predicting the secondary structure of globular proteins

1978 • 4,566 citations

Computed circular dichroism spectra for the evaluation of protein conformation

1969 • 3,654 citations

A graphics model building and refinement system for macromolecules

1978 • 1,858 citations

Primary structure, synthesis, and biological activity of rat endothelin, an endothelium-derived vasoconstrictor peptide.

1988 • 551 citations

Endothelin activates the dihydropyridine-sensitive, voltage-dependent Ca2+ channel in vascular smooth muscle.

1989 • 353 citations

Effects of quinine and apamin on the calcium‐dependent potassium permeability of mammalian hepatocytes and red cells.

1981 • 298 citations

Structure-activity relationships of endothelin: Importance of the C-terminal moiety

1988 • 220 citations

ENDOTHELIN: AN IMPORTANT FACTOR IN ACUTE RENAL FAILURE?

1988 • 214 citations

Sarafotoxins S6: Several isotoxins from Atractaspis engaddensis (burrowing asp) venom that affect the heart

1988 • 171 citations

Similarities in mode and sites of action of sarafotoxins and endothelins

1989 • 152 citations

Competitive interaction between endothelin and sarafotoxin: Binding and phosphoinositides hydrolysis in rat atria and brain

1989 • 143 citations

Solution structure of apamin determined by nuclear magnetic resonance and distance geometry

1988 • 101 citations

Endothelin induces potent microvascular constriction

1988 • 98 citations

Synthesis and disulfide structure determination of porcine endothelin: an endothelium‐derived vasoconstricting peptide

1988 • 89 citations

Differential activities of two distinct endothelin family peptides on ileum and coronary artery

1989 • 81 citations

Synthesis of Endothelin-1 Analogues, Endothelin-3, and Sarafotoxin S6b

1989 • 58 citations

Isolation and structure analysis of bee venom mast cell degranulating peptide

1987 • 56 citations

Autoradiographic localisation of endothelin binding sites in kidney

1989 • 56 citations

Origin of the positive 225–230 nm circular dichroism band in proteins

1988 • 46 citations

A comparative structural study of apamin and related bee venom peptides

1981 • 37 citations

A proposal for the structure of apamin

1980 • 31 citations

Functional studies on endothelin catch up with molecular biology

1989 • 27 citations

The conformation of apamin

1986 • 25 citations

Structure of P401 (mast cell degranulating peptide) in solution

1988 • 24 citations

Solid phase synthesis and biological activity of mast cell degranulating (MCD) peptide: a component of bee venom

1989 • 17 citations