Analysis of γ4 Germline Transcription in Human B Cells

Role of interleukin 10 in specific immunotherapy.

1998 • 980 citations

Serologic aspects of IgG4 antibodies. I. Prolonged immunization results in an IgG4-restricted response.

1983 • 727 citations

Immunoglobulin class switching

1996 • 446 citations

Structure and expression of germline epsilon transcripts in human B cells induced by interleukin 4 to switch to IgE production.

1990 • 353 citations

Specificity of immunoglobulin heavy chain switch correlates with activity of germline heavy chain genes prior to switching.

1986 • 344 citations

Immunoglobulin heavy-chain switching may be directed by prior induction of transcripts from constant-region genes.

1988 • 285 citations

Prominence of IgG4 in the IgG antibody response to human filariasis.

1985 • 263 citations

Control of allergic reactivity in human filariasis. Predominant localization of blocking antibody to the IgG4 subclass.

1992 • 223 citations

Serologic aspects of IgG4 antibodies. II. IgG4 antibodies form small, nonprecipitating immune complexes due to functional monovalency.

1986 • 181 citations

IgE responses in human filariasis. IV. Parallel antigen recognition by IgE and IgG4 subclass antibodies.

1986 • 129 citations

Sequential switching from mu to epsilon via gamma 4 in human B cells stimulated with IL-4 and hydrocortisone.

1993 • 109 citations

Strong serum inhibition of specific IgE correlated to competing IgG4, revealed by a new methodology in subjects from a S. mansoni endemic area

1992 • 93 citations

Switch circles from IL-4-directed epsilon class switching from human B lymphocytes. Evidence for direct, sequential, and multiple step sequential switch from mu to epsilon Ig heavy chain gene.

1994 • 88 citations

Production of sterile transcripts of C_γ genes in an IgM-producing human neoplastic B cell line that switches to IgG-producing cells

1989 • 74 citations

To E or not to E?Can an IL-4-Induced B Cell Choose between IgE and IgG4?

1998 • 72 citations

The transcription factor B cell-specific activator protein (BSAP) enhances both IL-4- and CD40-mediated activation of the human epsilon germline promoter.

1997 • 69 citations

Determinants and Mechanisms of Human Immune Responses to Bee Venom Phospholipase A<sub>2</sub>

1998 • 47 citations

Use of monoclonal antibodies to quantify subclasses of human IgG

1986 • 26 citations