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An N-terminally truncated third progesterone receptor protein, PRC, forms heterodimers with PRB but interferes in PRB-DNA binding

Data up to Jan 2025

Published1997
Citations70
References39

Total Citations Per Year

Abstract

References (39)

THE ATTRACTIONS OF PROTEINS FOR SMALL MOLECULES AND IONS

1949 • 19,979 citations

The Steroid and Thyroid Hormone Receptor Superfamily

1988 • 7,590 citations

MOLECULAR MECHANISMS OF ACTION OF STEROID/THYROID RECEPTOR SUPERFAMILY MEMBERS

1994 • 2,875 citations

Two distinct estrogen-regulated promoters generate transcripts encoding the two functionally different human progesterone receptor forms A and B.

1990 • 1,510 citations

The estrogen receptor binds tightly to its responsive element as a ligand-induced homodimer

1988 • 1,233 citations

Human progesterone receptor A form is a cell- and promoter-specific repressor of human progesterone receptor B function.

1993 • 749 citations

Molecular interactions of steroid hormone receptor with its enhancer element: Evidence for receptor dimer formation

1988 • 600 citations

Tripartite steroid hormone receptor pharmacology: interaction with multiple effector sites as a basis for the cell- and promoter-specific action of these hormones.

1996 • 505 citations

Identification of an Estrogen Response Element Activated by Metabolites of 17β-Estradiol and Raloxifene

1996 • 432 citations

Distinct classes of transcriptional activating domains function by different mechanisms

1990 • 368 citations

Hormone and antihormone induce distinct conformational changes which are central to steroid receptor activation.

1992 • 363 citations

The A and B isoforms of the human progesterone receptor operate through distinct signaling pathways within target cells.

1994 • 343 citations

Antagonist-occupied human progesterone B-receptors activate transcription without binding to progesterone response elements and are dominantly inhibited by A-receptors.

1993 • 330 citations

Tripartite steroid hormone receptor pharmacology: interaction with multiple effector sites as a basis for the cell- and promoter-specific action of these hormones

1996 • 285 citations

The Chicken Progesterone Receptor A and B Isoforms Are Products of an Alternate Translation Initiation Event

1989 • 196 citations

Multiple Human Progesterone Receptor Messenger Ribonucleic Acids and Their Autoregulation by Progestin Agonists and Antagonists in Breast Cancer Cells

1988 • 188 citations

Immunologic analysis of human breast cancer progesterone receptors. 1. Immunoaffinity purification of transformed receptors and production of monoclonal antibodies

1987 • 162 citations

The Purified Activated Glucocorticoid Receptor is a Homodimer

1989 • 156 citations

Human Progesterone Receptor Complexed with the Antagonist RU 486 Binds to Hormone Response Elements in a Structurally Altered Form

1989 • 138 citations

5′-Heterogeneity in Human Progesterone Receptor Transcripts Predicts a New Amino-Terminal Truncated “C”-Receptor and Unique A-Receptor Messages

1990 • 135 citations

Antagonist-occupied human progesterone B-receptors activate transcription without binding to progesterone response elements and are dominantly inhibited by A-receptors [published erratum appears in Mol Endocrinol 1993 Nov;7(11):1378]

1993 • 118 citations

An amino-terminal truncated progesterone receptor isoform, PRc, enhances progestin-induced transcriptional activity.

1996 • 111 citations

Characterization and Functional Properties of the A and B Forms of Human Progesterone Receptors Synthesized in a Baculovirus System

1991 • 105 citations

A Comparative Study of Antiestrogen Action: Temporal Patterns of Antagonism of Estrogen Stimulated Uterine Growth and Effects on Estrogen Receptor Levels123

1977 • 86 citations

Ligands induce conformational changes in the carboxyl-terminus of progesterone receptors which are detected by a site-directed antipeptide monoclonal antibody.

1992 • 81 citations

Antitumor activity of the antiprogestins ZK 98.299 and RU 38.486 in hormone dependent rat and mouse mammary tumors: Mechanistic studies

1989 • 80 citations

Immunologic analysis of human breast cancer progesterone receptors. 2. Structure, phosporylation, and processing

1987 • 75 citations

An amino-terminal truncated progesterone receptor isoform, PRc, enhances progestin-induced transcriptional activity

1996 • 74 citations

Evidence for the existence of a third progesterone receptor protein in human breast cancer cell line T47D.

1994 • 70 citations

Synthesis of Human Progesterone Receptors in T47D Cells

1989 • 64 citations

In vivo evidence against the existence of antiprogestins disrupting receptor binding to DNA.

1993 • 55 citations

86th Annual Meeting of the American Association for Cancer Research

1995 • 50 citations

Type II antagonists impair the DNA binding of steroid hormone receptors without affecting dimerization

1993 • 45 citations

Human progesterone A-receptors can be synthesized intracellularly and are biologically functional

1988 • 35 citations

Definition of the critical cellular components which distinguish between hormone and antihormone activated progesterone receptor

1995 • 28 citations

Mechanisms controlling steroid receptor binding to specific DNA sequences

1991 • 25 citations

The structure of progesterone receptors

1985 • 24 citations

Species crossreactivity of human progesterone receptor monoclonal antibodies: Western blot analysis

1988 • 11 citations

12th International Congress of Endocrinology

2003 • 2 citations

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