In vivo phosphorylation of the Na,K-ATPase alpha subunit in sciatic nerves of control and diabetic rats: effects of protein kinase modulators.

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters.

1982 • 4,786 citations

THE STRUCTURE AND REGULATION OF PROTEIN PHOSPHATASES

1989 • 2,518 citations

Fluorescent indicators for cytosolic calcium based on rhodamine and fluorescein chromophores

1989 • 1,616 citations

Isozymes of the Na+/K+-ATPase

1989 • 955 citations

Mechanism of the Na+, K+ pump protein structure and conformations of the pure

1982 • 500 citations

The Marcks brothers: A family of protein kinase C substrates

1992 • 474 citations

Molecular Genetics of Na,K-ATPase

1990 • 411 citations

Phosphorylation of the catalytic subunit of Na+,K(+)-ATPase inhibits the activity of the enzyme.

1991 • 307 citations

Complications: Neuropathy, Pathogenetic Considerations

1992 • 301 citations

Protein kinase C-stimulated phosphorylation in vitro of a Mr 80,000 protein phosphorylated in response to phorbol esters and growth factors in intact fibroblasts. Distinction from protein kinase C and prominence in brain.

1986 • 277 citations

Peripheral nerve structure and function in experimental diabetes

1974 • 266 citations

Impaired rat sciatic nerve sodium-potassium adenosine triphosphatase in acute streptozocin diabetes and its correction by dietary myo-inositol supplementation.

1983 • 246 citations

Identification of three isozyme proteins of the catalytic subunit of the Na,K-ATPase in rat brain

1989 • 212 citations

Hormonal regulation of (Na+,K+)-ATPase biosynthesis in the toad bladder. Effect of aldosterone and 3,5,3'-triiodo-L-thyronine.

1982 • 158 citations

Diminished ouabain-sensitive, sodium-potassium ATPase activity in sciatic nerves of rats with streptozotocin-induced diabetes

1976 • 135 citations

Na+-K+-ATPase is an effector protein for protein kinase C in renal proximal tubule cells

1989 • 134 citations

Fine specificity mapping and topography of an isozyme-specific epitope of the Na,K-ATPase catalytic subunit.

1988 • 123 citations

Protein phosphorylation in nerve terminals: comparison of calcium/calmodulin-dependent and calcium/diacylglycerol-dependent systems

1988 • 122 citations

Phosphorylation of Na,K-ATPase alpha-subunits in microsomes and in homogenates of Xenopus oocytes resulting from the stimulation of protein kinase A and protein kinase C.

1992 • 114 citations

Protein Kinase C Agonists Acutely Normalize Decreased Ouabain-inhibitable Respiration in Diabetic Rabbit Nerve: Implications for (Na,K)-ATPase Regulation and Diabetic Complications

1986 • 109 citations

Heterogeneity of protein kinase C-mediated rapid regulation of Na/K-ATPase in kidney epithelial cells

1993 • 106 citations

Kinetics of phosphorylation of Na+K+-ATPase by protein kinase C

1990 • 95 citations

Significance of Tissue myo -Inositol Concentrations in Metabolic Regulation in Nerve

1982 • 87 citations

Reversible sodium pump defect and swelling in the diabetic rat erythrocyte: effects on filterability and implications for microangiopathy.

1989 • 87 citations

Immunochemical evidence for a transmembrane orientation of both the (sodium(1+), potassium(1+) ion-activated)-ATPase subunits

1981 • 86 citations

The PO protein. The major glycoprotein of peripheral nerve myelin

1978 • 76 citations

1,2‐Diacylglycerol Content and Its Arachidonyl‐Containing Molecular Species Are Reduced in Sciatic Nerve from Streptozotocin‐induced Diabetic Rats

1990 • 68 citations

Diminished Specific Activity of Cytosolic Protein Kinase C In Sciatic Nerve of Streptozocin-Induced Diabetic Rats and Its Correction by Dietary myo-Inositol

1991 • 64 citations

α, βI, βII, δ, and ε Protein Kinase C Isoforms and Compound Activity in the Sciatic Nerve of Normal and Diabetic Rats

1994 • 60 citations

A myo-inositol pool utilized for phosphatidylinositol synthesis is depleted in sciatic nerve from rats with streptozotocin-induced diabetes.

1990 • 59 citations

Normalization of Na+-K+-ATPase Activity in Isolated Membrane Fraction From Sciatic Nerves of Streptozocin-Induced Diabetic Rats by Dietary myo-Inositol Supplementation in Vivo or Protein Kinase C Agonists in Vitro

1991 • 58 citations

In vitro correction of impaired Na+-K+-ATPase in diabetic nerve by protein kinase C agonists

1989 • 57 citations

Cyclic AMP inhibits inositol polyphosphate production and calcium mobilization in neuroblastoma X glioma NG108-15 cells.

1990 • 45 citations

Inhibition of Protein Kinase C Restores Na⁺, K⁺‐ATPase Activity in Sciatic Nerve of Diabetic Mice

1992 • 44 citations

Sustained Recovery of Na+-K+-ATPase Activity in Sciatic Nerve of Diabetic Mice by Administration of H7 or Calphostin C, Inhibitors of PKC

1993 • 40 citations

Cyclic adenosine 3',5'-monophosphate enhances sodium, potassium-adenosine triphosphatase activity in the sciatic nerve of streptozotocin-induced diabetic rats.

1993 • 36 citations

Relationship of ATP Turnover, Polyphosphoinositide Metabolism, and Protein Phosphorylation in Sciatic Nerve and Derived Peripheral Myelin Subfractions from Normal and Streptozotocin Diabetic Rats

1989 • 23 citations

Altered Protein Phosphorylation in Sciatic Nerve From Rats With Streptozocin-Induced Diabetes

1987 • 23 citations

Inositol Phospholipid Hydrolysis by Rat Sciatic Nerve Phospholipase C

1987 • 14 citations

Effects of Muscarinic Agonists and Depolarizing Agents on Inositol Monophosphate Accumulation in the Rabbit Vagus Nerve

1992 • 8 citations