Transfer of a TCR Gene Derived from a Patient with a Marked Antitumor Response Conveys Highly Active T-Cell Effector Functions

Cancer immunotherapy: moving beyond current vaccines

2004 • 2,932 citations

Cancer Regression and Autoimmunity in Patients After Clonal Repopulation with Antitumor Lymphocytes

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Use of Tumor-Infiltrating Lymphocytes and Interleukin-2 in the Immunotherapy of Patients with Metastatic Melanoma

1988 • 2,196 citations

Reconstitution of Cellular Immunity against Cytomegalovirus in Recipients of Allogeneic Bone Marrow by Transfer of T-Cell Clones from the Donor

1995 • 1,828 citations

Immunologic and therapeutic evaluation of a synthetic peptide vaccine for the treatment of patients with metastatic melanoma

1998 • 1,826 citations

Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma

2003 • 1,564 citations

Infusions of Donor Leukocytes to Treat Epstein-Barr Virus-Associated Lymphoproliferative Disorders after Allogeneic Bone Marrow Transplantation

1994 • 1,078 citations

Adoptive immunotherapy evaluating escalating doses of donor leukocytes for relapse of chronic myeloid leukemia after bone marrow transplantation: separation of graft-versus-leukemia responses from graft-versus-host disease

1995 • 772 citations

Versatile retroviral vectors for potential use in gene therapy.

1994 • 690 citations

Generation of Tumor-Infiltrating Lymphocyte Cultures for Use in Adoptive Transfer Therapy for Melanoma Patients

2003 • 662 citations

Adoptive-cell-transfer therapy for the treatment of patients with cancer

2003 • 656 citations

Genes regulating HLA class I antigen expression in T-B lymphoblast hybrids

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Colocalization of retrovirus and target cells on specific fibronectin fragments increases genetic transduction of mammalian cells

1996 • 565 citations

Expression of Two T Cell Receptor α Chains: Dual Receptor T Cells

1993 • 527 citations

Tumor-specific cytolysis by lymphocytes infiltrating human melanomas.

1989 • 511 citations

Targeting tumours with genetically enhanced T lymphocytes

2003 • 508 citations

Induction of primary NY-ESO-1 immunity: CD8+ T lymphocyte and antibody responses in peptide-vaccinated patients with NY-ESO-1+ cancers

2000 • 435 citations

Ex vivo identification, isolation and analysis of tumor-cytolytic T cells

2003 • 410 citations

Efficient Transfer of a Tumor Antigen-Reactive TCR to Human Peripheral Blood Lymphocytes Confers Anti-Tumor Reactivity

1999 • 406 citations

High Avidity CTLs for Two Self-Antigens Demonstrate Superior In Vitro and In Vivo Antitumor Efficacy

1999 • 388 citations

Circumventing tolerance to a human MDM2-derived tumor antigen by TCR gene transfer

2001 • 373 citations

Adoptive Transfer of Cloned Melanoma-Reactive T Lymphocytes for the Treatment of Patients with Metastatic Melanoma

2001 • 359 citations

A Phase I Study of Nonmyeloablative Chemotherapy and Adoptive Transfer of Autologous Tumor Antigen-Specific T Lymphocytes in Patients With Metastatic Melanoma

2002 • 340 citations

Immunotherapy through TCR gene transfer

2001 • 287 citations

T-cell-receptor gene therapy

2002 • 266 citations

High Efficiency TCR Gene Transfer into Primary Human Lymphocytes Affords Avid Recognition of Melanoma Tumor Antigen Glycoprotein 100 and Does Not Alter the Recognition of Autologous Melanoma Antigens

2003 • 231 citations

How Much TCR Does a T Cell Need?

2001 • 224 citations

Retroviral vectors containing putative internal ribosome entry sites: development of a polycistronic gene transfer system and applications to human gene therapy

1992 • 211 citations

Interleukin 4 promotes the growth of tumor-infiltrating lymphocytes cytotoxic for human autologous melanoma.

1988 • 160 citations

Peptide Fine Specificity of Anti-Glycoprotein 100 CTL Is Preserved Following Transfer of Engineered TCRαβ Genes Into Primary Human T Lymphocytes

2003 • 145 citations

Recognition of Shared Melanoma Antigens in Association With Major HLA-A Alleles by Tumor Infiltrating T Lymphocytes From 123 Patients With Melanoma

2000 • 121 citations

T Cells Associated with Tumor Regression Recognize Frameshifted Products of the CDKN2A Tumor Suppressor Gene Locus and a Mutated HLA Class I Gene Product

2004 • 103 citations

Transduction of an IL-2 Gene into Human Melanoma-Reactive Lymphocytes Results in Their Continued Growth in the Absence of Exogenous IL-2 and Maintenance of Specific Antitumor Activity

2001 • 102 citations

Comparative Analysis of the In Vivo Expression of Tyrosinase, MART-1/Melan-A, and gp100 in Metastatic Melanoma Lesions: Implications for Immunotherapy

1998 • 94 citations

Sustained Gene Expression in Retrovirally Transduced, Engrafting Human Hematopoietic Stem Cells and Their Lympho-Myeloid Progeny

1998 • 88 citations

Isolation of a New Melanoma Antigen, MART-2, Containing a Mutated Epitope Recognized by Autologous Tumor-Infiltrating T Lymphocytes

2001 • 70 citations

CD8-Independent Tumor Cell Recognition Is a Property of the T Cell Receptor and Not the T Cell

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Genetic engineering of T cell specificity for immunotherapy of cancer

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Versatile Retrovirus Vector Systems for Regulated Gene Expression In Vitro and In Vivo

1997 • 58 citations

Development of Improved Adenosine Deaminase Retroviral Vectors

1998 • 57 citations

A Simple and Reliable Method for Screening Retroviral Producer Clones Without Selectable Markers

1997 • 57 citations

Transfer of TCR Genes into Mature T Cells Is Accompanied by the Maintenance of Parental T Cell Avidity

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Retroviral Vectors for Production of Interleukin‐12 in the Bone Marrow to Induce a Graft‐Versus‐Leukemia Effecta

1996 • 43 citations

Expression of melan-a/MART-1 antigen as a prognostic factor in primary cutaneous melanoma

2001 • 40 citations

Nucleosome-Specific Regulatory T Cells Engineered by Triple Gene Transfer Suppress a Systemic Autoimmune Disease

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Melanoma-Reactive CD8 + T Cells Recognize a Novel Tumor Antigen Expressed in a Wide Variety of Tumor Types

2001 • 33 citations

Reviews in Computational Chemistry, Volume 10

1997 • 10 citations

Reviews in Computational Chemistry, Volume 9

1997 • 8 citations