ADP-ribosylation Factor-dependent Phospholipase D2 Activation Is Required for Agonist-induced μ-Opioid Receptor Endocytosis

Calcium phosphate-mediated gene transfer: a highly efficient transfection system for stably transforming cells with plasmid DNA.

1988 • 897 citations

μ-Opioid receptor desensitization by β-arrestin-2 determines morphine tolerance but not dependence

2000 • 869 citations

Phosphatidylinositol 4-Phosphate 5-Kinase α Is a Downstream Effector of the Small G Protein ARF6 in Membrane Ruffle Formation

1999 • 800 citations

Phosphoinositides as Regulators in Membrane Traffic

1996 • 717 citations

Phospholipase D2, a distinct phospholipase D isoform with novel regulatory properties that provokes cytoskeletal reorganization

1997 • 698 citations

Human ADP-ribosylation Factor-activated Phosphatidylcholine-specific Phospholipase D Defines a New and Highly Conserved Gene Family

1995 • 663 citations

Role for G protein-coupled receptor kinase in agonist-specific regulation of μ-opioid receptor responsiveness

1998 • 501 citations

Phospholipase D: molecular and cell biology of a novel gene family

2000 • 495 citations

Functional Dissociation of μ Opioid Receptor Signaling and Endocytosis

1999 • 422 citations

Evidence that phospholipase D mediates ADP ribosylation factor-dependent formation of Golgi coated vesicles.

1996 • 380 citations

Phosphatidic acid is a specific activator of phosphatidylinositol-4-phosphate kinase.

1992 • 368 citations

Lipid second messengers

1994 • 357 citations

Homo- and Heterodimerization of Somatostatin Receptor Subtypes

2001 • 312 citations

Signal transduction and membrane traffic: The PITP/phosphoinositide connection

1995 • 261 citations

Heterodimerization of Somatostatin and Opioid Receptors Cross-modulates Phosphorylation, Internalization, and Desensitization

2002 • 259 citations

Identification of a Family of Sorting Nexin Molecules and Characterization of Their Association with Receptors

1998 • 239 citations

Cloning, Expression, and Characterization of a Novel Phospholipase D Complementary DNA from Rat Brain

1997 • 227 citations

Role for Phospholipase D in Receptor-Mediated Endocytosis

2001 • 216 citations

Rhodopsin-family receptors associate with small G proteins to activate phospholipase D

1998 • 211 citations

Measurement of Phospholipase D Activity

1997 • 202 citations

Phospholipase D is present on Golgi-enriched membranes and its activation by ADP ribosylation factor is sensitive to brefeldin A.

1995 • 193 citations

Structural Analysis of Human Phospholipase D1

1999 • 169 citations

C-terminal Splice Variants of the Mouse µ-Opioid Receptor Differ in Morphine-induced Internalization and Receptor Resensitization

2001 • 162 citations

β-Arrestin/AP-2 Interaction in G Protein-coupled Receptor Internalization

2002 • 143 citations

Cloning and Characterization of Phospholipase D from Rat Brain

1997 • 137 citations

μ and δ Opioid Receptors Are Differentially Desensitized by the Coexpression of β-Adrenergic Receptor Kinase 2 and β-Arrestin 2 in Xenopus Oocytes

1997 • 135 citations

The Phox homology (PX) domain, a new player in phosphoinositide signalling

2001 • 128 citations

PLD2 Complexes with the EGF Receptor and Undergoes Tyrosine Phosphorylation at a Single Site upon Agonist Stimulation

1998 • 116 citations

Phospholipase D

1998 • 104 citations

Mechanism of ADP Ribosylation Factor-stimulated Phosphatidylinositol 4,5-Bisphosphate Synthesis in HL60 Cells

2002 • 102 citations

Coupling of transfected muscarinic acetylcholine receptor subtypes to phospholipase D.

1991 • 98 citations

The Phox homology (PX) domain, a new player in phosphoinositide signalling

2001 • 90 citations

Identification and Characterization of SNX15, a Novel Sorting Nexin Involved in Protein Trafficking

2001 • 88 citations

Alpha 2-C10 adrenergic receptors expressed in rat 1 fibroblasts can regulate both adenylylcyclase and phospholipase D-mediated hydrolysis of phosphatidylcholine by interacting with pertussis toxin-sensitive guanine nucleotide-binding proteins.

1992 • 84 citations

Regulation of phospholipase D by protein kinase C

1996 • 75 citations

Ethanol Inhibits Astroglial Cell Proliferation by Disruption of Phospholipase D‐Mediated Signaling

1999 • 74 citations

Regulation of phospholipase D by tyrosine kinases

1996 • 64 citations

The D2s Dopamine Receptor Stimulates Phospholipase D Activity: A Novel Signaling Pathway for Dopamine

2000 • 60 citations

ADP-Ribosylation Factor-Dependent Phospholipase D Activation by VPAC Receptors and a PAC₁Receptor Splice Variant

2001 • 57 citations

Endothelin receptors stimulate both phospholipase C and phospholipase D activities in different cell lines

1993 • 51 citations

Activation of phospholipase D by metabotropic glutamate receptor agonists in rat cerebrocortical synaptosomes

2000 • 21 citations

Functional coupling of rat metabotropic glutamate 1a receptors to phospholipase D in CHO cells: involvement of extracellular Ca2+, protein kinase C, tyrosine kinase and Rho-A

2002 • 19 citations