Angiotensin-Converting Enzyme Inhibition Abolishes Medial Smooth Muscle PDGF-AB Biosynthesis and Attenuates Cell Proliferation in Injured Carotid Arteries

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Kinetics of cellular proliferation after arterial injury. I. Smooth muscle growth in the absence of endothelium.

1983 • 1,441 citations

Inhibitors of Angiotensin-Converting Enzyme Prevent Myointimal Proliferation After Vascular Injury

1989 • 1,061 citations

Restenosis after coronary angioplasty. Potential biologic determinants and role of intimal hyperplasia.

1989 • 935 citations

Angiotensin II induces smooth muscle cell proliferation in the normal and injured rat arterial wall.

1991 • 751 citations

Proliferation of smooth muscle cells after vascular injury is inhibited by an antibody against basic fibroblast growth factor.

1991 • 722 citations

Platelet-derived growth factor promotes smooth muscle migration and intimal thickening in a rat model of balloon angioplasty.

1992 • 681 citations

Does the new angiotensin converting enzyme inhibitor cilazapril prevent restenosis after percutaneous transluminal coronary angioplasty? Results of the MERCATOR study: a multicenter, randomized, double-blind placebo-controlled trial. Multicenter European Research Trial with Cilazapril after Angioplasty to Prevent Transluminal Coronary Obstruction and Restenosis (MERCATOR) Study Group.

1992 • 548 citations

Multiple autocrine growth factors modulate vascular smooth muscle cell growth response to angiotensin II.

1993 • 470 citations

PDGF ligand and receptor gene expression during repair of arterial injury.

1990 • 431 citations

Production of platelet-derived growth factor-like molecules by cultured arterial smooth muscle cells accompanies proliferation after arterial injury.

1986 • 393 citations

Translocation of bFGF to the nucleus is G1 phase cell cycle specific in bovine aortic endothelial cells.

1990 • 324 citations

Role of angiotensin subtype 2 receptor in neointima formation after vascular injury.

1992 • 221 citations

Sera and conditioned media contain different isoforms of platelet-derived growth factor (PDGF) which bind to different classes of PDGF receptor

1989 • 216 citations

Role of PDGF-A expression in the control of vascular smooth muscle cell growth by transforming growth factor-beta.

1990 • 214 citations

Multiple Forms of bFGF: Differential Nuclear and Cell Surface Localization

1991 • 210 citations

Arterial smooth muscle cells express platelet-derived growth factor (PDGF) A chain mRNA, secrete a PDGF-like mitogen, and bind exogenous PDGF in a phenotype- and growth state-dependent manner

1988 • 205 citations

Angiotensin-converting enzyme inhibitor versus angiotensin II, AT1 receptor antagonist. Effects on smooth muscle cell migration and proliferation after balloon catheter injury.

1991 • 193 citations

Expression of basic fibroblast growth factor and its receptor by smooth muscle cells and endothelium in injured rat arteries. An en face study.

1993 • 174 citations

Identification of a cell retention signal in the B-chain of platelet-derived growth factor and in the long splice version of the A-chain.

1991 • 139 citations

Effects of angiotensin converting enzyme inhibition with cilazapril on intimal hyperplasia in injured arteries and vascular grafts in the baboon.

1991 • 138 citations

Vascular derived growth factors: cell biology, pathophysiology, and pharmacology.

1993 • 133 citations

Regulatory effects of platelet-derived growth factor-AA homodimer on migration of vascular smooth muscle cells

1992 • 119 citations

PDGF-AA and PDGF-BB biosynthesis: proprotein processing in the Golgi complex and lysosomal degradation of PDGF-BB retained intracellularly.

1992 • 85 citations

Identification of serum-inducible genes: Different patterns of gene regulation during g0→s and g1→s progression

1994 • 79 citations

Chronic ACE Inhibition Reduces Intimal Hyperplasia in Experimental Vein Grafts

1991 • 78 citations

Structural and functional properties of ribosomal protein L7 from humans and rodents

1993 • 77 citations

Cilazapril and early atherosclerotic changes after balloon injury of porcine carotid arteries.

1992 • 76 citations

Monoclonal antibodies directed against basic fibroblast growth factor which inhibit its biological activity in vitro and in vivo

1989 • 72 citations

Internephron heterogeneity of growth factors and sclerosis—Modulation of platelet-derived growth factor by angiotensin II

1995 • 55 citations

Expression of growth factor receptors on arterial smooth muscle cells. Dependency on cell phenotype and serum factors

1995 • 44 citations

Restenosis after percutaneous transluminal coronary angioplasty. A histopathological study using autopsied hearts.

1990 • 43 citations

Measurement of protein using flow injection analysis with bicinchoninic acid

1987 • 37 citations

Mechanism of Inhibition of Neointimal Formation by the Angiotensin-Converting Enzyme Inhibitor Cilazapril

1995 • 34 citations

Pathophysiological mechanisms for restenosis following coronary angioplasty: possible preventive alternatives

1993 • 30 citations

Methodologic considerations important in the accurate quantitation of aortic smooth muscle cell replication in the normal rat.

1991 • 25 citations

Effect of converting enzyme inhibition on allograft-induced arterial wall injury and response.

1991 • 22 citations