Internephron heterogeneity of growth factors and sclerosis—Modulation of platelet-derived growth factor by angiotensin II

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Genomic sequencing.

1984 • 8,343 citations

Hyperfiltration in remnant nephrons: a potentially adverse response to renal ablation

1981 • 1,664 citations

Therapeutic advantage of converting enzyme inhibitors in arresting progressive renal disease associated with systemic hypertension in the rat.

1986 • 1,071 citations

Inhibitors of Angiotensin-Converting Enzyme Prevent Myointimal Proliferation After Vascular Injury

1989 • 1,061 citations

Mesangial immune injury, hypertension, and progressive glomerular damage in Dahl rats

1984 • 677 citations

Vascular smooth muscle cell hypertrophy vs. hyperplasia. Autocrine transforming growth factor-beta 1 expression determines growth response to angiotensin II.

1992 • 648 citations

Induction of platelet-derived growth factor A-chain and c-myc gene expressions by angiotensin II in cultured rat vascular smooth muscle cells.

1989 • 632 citations

Localization of PDGF-B Protein in Macrophages in All Phases of Atherogenesis

1990 • 584 citations

Renal injury from angiotensin II-mediated hypertension.

1992 • 546 citations

PDGF ligand and receptor gene expression during repair of arterial injury.

1990 • 431 citations

Endogenous angiotensin concentrations in specific intrarenal fluid compartments of the rat.

1990 • 421 citations

Glomerular cell proliferation and PDGF expression precede glomerulosclerosis in the remnant kidney model

1992 • 404 citations

Angiotensin II Induces c-fos mRNA in Aortic Smooth Muscle

1989 • 401 citations

Validity of an indirect tail-cuff method for determining systolic arterial pressure in unanesthetized normotensive and spontaneously hypertensive rats.

1971 • 391 citations

Activated human monocytes express the c-sis proto-oncogene and release a mediator showing PDGF-like activity

1986 • 380 citations

Glomerular hemodynamic changes vs. hypertrophy in experimental glomerular sclerosis

1989 • 354 citations

Angiotensin II receptor blockade limits glomerular injury in rats with reduced renal mass.

1992 • 352 citations

Inhibition of mesangial cell proliferation and matrix expansion in glomerulonephritis in the rat by antibody to platelet-derived growth factor.

1992 • 345 citations

In situ hybridization evidence for angiotensinogen messenger RNA in the rat proximal tubule. An hypothesis for the intrarenal renin angiotensin system.

1990 • 325 citations

Platelet-derived growth factor (PDGF) and PDGF receptor are induced in mesangial proliferative nephritis in the rat.

1991 • 293 citations

Effects of antihypertensive drugs on glomerular morphology

1989 • 227 citations

Selective expression of PDGF A and its receptor during early mouse embryogenesis

1990 • 215 citations

Mesangial cells express PDGF mRNAs and proliferate in response to PDGF

1988 • 191 citations

Blood pressure-independent effect of angiotensin inhibition on vascular lesions of chronic renal failure

1992 • 166 citations

Potent, orally active imidazo[4,5-b]pyridine-based angiotensin II receptor antagonists

1991 • 161 citations

Cause of variable therapeutic efficiency of angiotensin converting enzyme inhibitor on glomerular lesions

1991 • 150 citations

Continuous stretch-relaxation in culture alters rat mesangial cell morphology, growth characteristics, and metabolic activity.

1992 • 136 citations

Mechanisms underlying transition from acute glomerular injury to late glomerular sclerosis in a rat model of nephrotic syndrome.

1988 • 130 citations

Losartan, a nonpeptide angiotensin II (Ang II) receptor antagonist, inhibits neointima formation following balloon injury to rat carotid arteries

1991 • 125 citations

Focal and segmental glomerulosclerosis following a single intravenous dose of puromycin aminonucleoside.

1986 • 123 citations

Long-term enalapril and verapamil in rats with reduced renal mass

1989 • 120 citations

Demonstration of PDGF B-chain mRNA in glomeruli in mesangial proliferative nephritis by in situ hybridization

1991 • 110 citations

PDGF-receptor localizes to mesangial, parietal epithelial, and interstitial cells in human and primate kidneys

1993 • 110 citations

In vitro pharmacology of L-158,809, a new highly potent and selective angiotensin II receptor antagonist.

1992 • 109 citations

Mechanical strain and collagen potentiate mitogenic activity of angiotensin II in rat vascular smooth muscle cells.

1993 • 103 citations

In vivo pharmacology of L-158,809, a new highly potent and selective nonpeptide angiotensin II receptor antagonist.

1992 • 95 citations

Angiotensin converting enzyme inhibitor modulates glomerular function and structure by distinct mechanisms

1994 • 95 citations

Intrarenal localization of angiotensin II type 1 receptor mRNA in the rat

1993 • 79 citations

MOLECULAR EVIDENCE FOR THE PRESENCE OF GROWTH HORMONE RECEPTORS IN THE BOVINE MAMMARY GLAND

1990 • 74 citations

The contribution of increased collagen synthesis to human glomerulosclerosis: a quantitative analysis of alpha 2IV collagen mRNA expression by competitive polymerase chain reaction.

1992 • 73 citations

Fibroblasts of rabbit kidney in culture. II. Paracrine stimulation of papillary fibroblasts by PDGF

1991 • 70 citations

Radioimmunoassay of human platelet-derived growth factor using monoclonal antibody toward a synthetic 73–97 fragment of its B-chain

1989 • 55 citations

Spatial organization of the extracellular matrix modulates the expression of PDGF-receptor subunits in mesangial cells

1993 • 43 citations

Identification of three types of PDGF-A chain gene transcripts in rabbit vascular smooth muscle and their regulated expression during development and by angiotensin II

1992 • 39 citations

Effect of angiotensin II and norepinephrine on early growth response genes in the rat kidney

1993 • 38 citations

Subpressor angiotensin II is a bifunctional growth factor of vascular muscle in rats

1992 • 33 citations

Overview and principles of in-situ hybridization

1990 • 23 citations

Determinants of angiotensin II‐induced hypertrophy versus hyperplasia in vascular smooth muscle

1993 • 15 citations