Molecular and Clinical Aspects of Inherited Cardiomyopathies

Single myosin molecule mechanics: piconewton forces and nanometre steps

1994 • 1,894 citations

Analysis of Human Genetic Linkage.

1992 • 1,770 citations

A second-generation linkage map of the human genome

1992 • 1,721 citations

Regular physical exercise and low-fat diet. Effects on progression of coronary artery disease.

1992 • 1,349 citations

α-tropomyosin and cardiac troponin T mutations cause familial hypertrophic cardiomyopathy: A disease of the sarcomere

1994 • 1,008 citations

The natural history of idiopathic dilated cardiomyopathy

1981 • 957 citations

Characteristics and Prognostic Implications of Myosin Missense Mutations in Familial Hypertrophic Cardiomyopathy

1992 • 732 citations

The Frequency of Familial Dilated Cardiomyopathy in a Series of Patients with Idiopathic Dilated Cardiomyopathy

1992 • 704 citations

Developmental and functional adaptation of contractile proteins in cardiac and skeletal muscles

1986 • 657 citations

Analysis of Human Genetic Linkage

1992 • 555 citations

Mapping a Gene for Familial Hypertrophic Cardiomyopathy to Chromosome 14q1

1989 • 526 citations

Myosin Structure and Function in Cell Motility

1987 • 479 citations

Prevalence and etiology of idiopathic dilated cardiomyopathy (summary of a National Heart, Lung, and Blood Institute Workshop)

1992 • 443 citations

Angiotensin-converting enzyme polymorphism in hypertrophic cardiomyopathy and sudden cardiac death

1993 • 412 citations

Prognostic implications of novel beta cardiac myosin heavy chain gene mutations that cause familial hypertrophic cardiomyopathy.

1994 • 289 citations

Skeletal muscle expression and abnormal function of beta-myosin in hypertrophic cardiomyopathy.

1993 • 239 citations

Differences in clinical expression of hypertrophic cardiomyopathy associated with two distinct mutations in the beta-myosin heavy chain gene. A 908Leu----Val mutation and a 403Arg----Gln mutation.

1992 • 232 citations

Genotype-phenotype correlations in hypertrophic cardiomyopathy. Insights provided by comparisons of kindreds with distinct and identical beta-myosin heavy chain gene mutations.

1994 • 223 citations

Heterologous expression of a cardiomyopathic myosin that is defective in its actin interaction.

1994 • 202 citations

A disease locus for familial hypertrophic cardiomyopathy maps to chromosome 1q3

1993 • 191 citations

Mapping of a novel gene for familial hypertrophic cardiomyopathy to chromosome 11

1993 • 186 citations

A gene defect that causes conduction system disease and dilated cardiomyopathy maps to chromosome 1p1–1q1

1994 • 183 citations

A familial hypertrophic cardiomyopathy locus maps to chromosome 15q2.

1993 • 177 citations

Sudden cardiac death in hypertrophic cardiomyopathy

1995 • 132 citations

Complete sequence and organization of the human cardiac β-myosin heavy chain gene

1990 • 131 citations

Expression of a Mutation Causing Hypertrophic Cardiomyopathy Disrupts Sarcomere Assembly in Adult Feline Cardiac Myocytes

1995 • 83 citations

Localization of gene for familial hypertrophic cardiomyopathy to chromosome 14q1 in a diverse US population.

1991 • 82 citations

Hurst's the Heart: Arteries and Veins

1995 • 81 citations

Expression of a missense mutation in the messenger RNA for beta-myosin heavy chain in myocardial tissue in hypertrophic cardiomyopathy.

1992 • 49 citations

MOLECULAR GENETICS OF HYPERTROPHIC CARDIOMYOPATHY

1995 • 29 citations

Familial idiopathic dilated cardiomyopathy

1988 • 28 citations

Isolation of a de novo mutant myocardial beta MHC protein in a pedigree with hypertrophic cardiomyopathy.

1994 • 26 citations

Familial dilated cardiomyopathy

1988 • 24 citations

Accumulation and assembly of myosin in hypertrophic cardiomyopathy with the 403 Arg to Gln beta-myosin heavy chain mutation.

1992 • 22 citations

Molecular Basis of Cardiology.

1993 • 17 citations