Prognostic implications of novel beta cardiac myosin heavy chain gene mutations that cause familial hypertrophic cardiomyopathy.

Three-dimensional structure of myosin subfragment-1: a molecular motor

1993 • 2,027 citations

Structure of the actin-myosin complex and its implications for muscle contraction

1993 • 1,756 citations

A molecular basis for familial hypertrophic cardiomyopathy: A β cardiac myosin heavy chain gene missense mutation

1990 • 1,332 citations

An Improved Method for Prenatal Diagnosis of Genetic Diseases by Analysis of Amplified DNA Sequences

1987 • 811 citations

Characteristics and Prognostic Implications of Myosin Missense Mutations in Familial Hypertrophic Cardiomyopathy

1992 • 732 citations

Reactivity of cytosine and thymine in single-base-pair mismatches with hydroxylamine and osmium tetroxide and its application to the study of mutations.

1988 • 636 citations

Mapping a Gene for Familial Hypertrophic Cardiomyopathy to Chromosome 14q1

1989 • 526 citations

Skeletal muscle expression and abnormal function of beta-myosin in hypertrophic cardiomyopathy.

1993 • 239 citations

Differences in clinical expression of hypertrophic cardiomyopathy associated with two distinct mutations in the beta-myosin heavy chain gene. A 908Leu----Val mutation and a 403Arg----Gln mutation.

1992 • 232 citations

Missense mutations in the beta-myosin heavy-chain gene cause central core disease in hypertrophic cardiomyopathy.

1993 • 203 citations

A disease locus for familial hypertrophic cardiomyopathy maps to chromosome 1q3

1993 • 191 citations

Preclinical Diagnosis of Familial Hypertrophic Cardiomyopathy by Genetic Analysis of Blood Lymphocytes

1991 • 186 citations

Mapping of a novel gene for familial hypertrophic cardiomyopathy to chromosome 11

1993 • 186 citations

The complete sequence of the human β-myosin heavy chain gene and a comparative analysis of its product

1990 • 178 citations

A familial hypertrophic cardiomyopathy locus maps to chromosome 15q2.

1993 • 177 citations

Sporadic hypertrophic cardiomyopathy due to de novo myosin mutations.

1992 • 143 citations

Left ventricular hypertrophy and morphology in familial hypertrophic cardiomyopathy associated with mutations of the beta-myosin heavy chain gene

1993 • 109 citations

Detection of a new mutation in the beta-myosin heavy chain gene in an individual with hypertrophic cardiomyopathy.

1992 • 85 citations

Localization of gene for familial hypertrophic cardiomyopathy to chromosome 14q1 in a diverse US population.

1991 • 82 citations

Functions of the myosin ATP and actin binding sites are required for C. elegans thick filament assembly

1990 • 80 citations

Expression of a missense mutation in the messenger RNA for beta-myosin heavy chain in myocardial tissue in hypertrophic cardiomyopathy.

1992 • 49 citations

Novel missense mutation in cardiac β myosin heavy chain gene found in a japanese patient with hypertrophic cardiomyopathy

1992 • 46 citations

Familial cardiomyopathy

1964 • 27 citations

Identification of a mutation in the beta cardiac myosin heavy chain gene in a family with hypertrophic cardiomyopathy.

1993 • 26 citations

Familial cardiomyopathy

1965 • 19 citations

Sporadic hypertrophic cardiomyopathy due to de novo myosin mutations

1992 • 9 citations

Familial cardiomyopathy in a Milwaukee family.

1972 • 2 citations