Characterisation of a novel Ca2+ pump inhibitor (bis-phenol) and its effects on intracellular Ca2+ mobilization

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

1985 • 21,873 citations

Energy Interconversion by the Ca2+-Dependent ATPase of the Sarcoplasmic Reticulum

1979 • 718 citations

Functional comparisons between isoforms of the sarcoplasmic or endoplasmic reticulum family of calcium pumps.

1992 • 649 citations

cDNA Cloning, functional expression, and mRNA Tissue Distribution of a Third Organellar Ca2+ Pump

1989 • 412 citations

Molecular cloning of cDNAs from human kidney coding for two alternatively spliced products of the cardiac Ca2+-ATPase gene.

1988 • 374 citations

A novel Ca2+ pump expressed in brain, kidney, and stomach is encoded by an alternative transcript of the slow-twitch muscle sarcoplasmic reticulum Ca-ATPase gene. Identification of cDNAs encoding Ca2+ and other cation-transporting ATPases using an oligonucleotide probe derived from the ATP-binding site.

1988 • 268 citations

2,5-Di-(tert-butyl)-1,4-benzohydroquinone rapidly elevates cytosolic Ca2+ concentration by mobilizing the inositol 1,4,5-trisphosphate-sensitive Ca2+ pool

1989 • 261 citations

Identification of intracellular calcium pools. Selective modification by thapsigargin

1991 • 238 citations

The Ca2+-pumping ATPase of plasma membranes purification, reconstitution and properties

1982 • 221 citations

2,5‐Di(tert‐butyl)‐1,4‐benzohydroquinone — a novel inhibitor of liver microsomal Ca²⁺ sequestration

1987 • 204 citations

Distribution of two distinct Ca2+ -ATPase-like proteins and their relationships to the agonist-sensitive calcium store in adrenal chromaff in cells

1989 • 185 citations

Activation of inositol phospholipid breakdown in HL60 cells by P2-purinergic receptors for extracellular ATP. Evidence for mediation by both pertussis toxin-sensitive and pertussis toxin-insensitive mechanisms.

1988 • 166 citations

Demonstration of two forms of calcium pumps by thapsigargin inhibition and radioimmunoblotting in platelet membrane vesicles

1991 • 132 citations

A conformational mechanism for formation of a dead-end complex by the sarcoplasmic reticulum ATPase with thapsigargin.

1992 • 127 citations

A kinetic model for the Ca2+ + Mg2+-activated ATPase of sarcoplasmic reticulum

1986 • 106 citations

Simultaneous presence of two distinct endoplasmic-reticulum-type calcium-pump isoforms in human cells. Characterization by radio-immunoblotting and inhibition by 2,5-di-(t-butyl)-1,4-benzohydroquinone

1992 • 106 citations

The opening of the inositol 1,4,5-trisphosphate-sensitive Ca2+ channel in rat cerebellum is inhibited by caffeine

1992 • 104 citations

The inhibitors thapsigargin and 2,5‐di(tert‐butyl)‐1,4‐benzohydroquinone favour the E2 form of the Ca²⁺, Mg²⁺‐ATPase

1992 • 96 citations

Mechanism of inhibition of the calcium pump of sarcoplasmic reticulum by thapsigargin

1992 • 90 citations

Inositol trisphosphate and thapsigargin discriminate endoplasmic reticulum stores of calcium in rat brain

1990 • 90 citations

Comparison between the effects of the microsomal Ca2+-translocase inhibitors thapsigargin and 2,5-di-(t-butyl)-1,4-benzohydroquinone on cellular calcium fluxes

1991 • 89 citations

Kinetic characterization of detergent-solubilized sarcoplasmic reticulum ATPase

1983 • 87 citations

Mechanism of inhibition of the calcium-magnesium ATPase by nonylphenol

1990 • 81 citations

The effects of thimerosal on calcium uptake and inositol 1,4,5-trisphosphate-induced calcium release in cerebellar microsomes

1993 • 78 citations

Ca2+ influx induced by the Ca2+-ATPase inhibitors 2,5-di-(t-butyl)-1,4-benzohydroquinone and thapsigargin in bovine adrenal chromaffin cells

1992 • 69 citations

Conformational transitions in the Ca2+ + Mg2+-activated ATPase and the binding of Ca2+ ions

1986 • 63 citations

Identification, kinetic properties and intracellular localization of the (Ca2+-Mg2+)-ATPase from the intracellular stores of chicken cerebellum

1991 • 47 citations

Phenolic antioxidants: potent inhibitors of the (Ca²⁺ + Mg²⁺‐ATPase of sarcoplasmic reticulum

1986 • 46 citations

2,5‐Di‐(tert‐butyl)‐1,4‐benzohydroquinone mobilizes inositol 1,4,5‐trisphosphate‐sensitive and ‐insensitive Ca²⁺ stores

1990 • 43 citations

Methods of reconstitution of the purified sarcoplasmic reticulum (Ca2+Mg2+)-ATPase using bile salt detergents to form membranes of defined lipid to protein ratios or sealed vesicles

1991 • 39 citations

Effect of pH on the activity of the Ca2+ + Mg2+-activated ATPase of sarcoplasmic reticulum

1990 • 35 citations

Inhibition of Sarcoplasmic Reticulum Ca2+-ATPase by 2,5-Di(Tert-Butyl)-1,4-Benzohydroquinon1

1992 • 24 citations

The effects of amino acid-reactive reagents on the functioning of the inositol 1,4,5-trisphosphate-sensitive calcium channel from rat cerebellum

1993 • 17 citations

The role of a (Ca2+ + Mg2+)-ATPase of the rough endoplasmic reticulum in regulating intracellular Ca2+ during cholinergic stimulation of rat pancreatic acini

1987 • 16 citations