2,5-Di-(tert-butyl)-1,4-benzohydroquinone rapidly elevates cytosolic Ca2+ concentration by mobilizing the inositol 1,4,5-trisphosphate-sensitive Ca2+ pool

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

1985 • 21,873 citations

DETERMINATION OF SERUM PROTEINS BY MEANS OF THE BIURET REACTION

1949 • 16,078 citations

A model for receptor-regulated calcium entry

1986 • 2,535 citations

INTRACELLULAR CALCIUM HOMEOSTASIS

1987 • 2,183 citations

Changes in the levels of inositol phosphates after agonist-dependent hydrolysis of membrane phosphoinositides

1983 • 1,937 citations

[4] Isolation and use of liver cells

1978 • 1,230 citations

Repetitive transient rises in cytoplasmic free calcium in hormone-stimulated hepatocytes

1986 • 790 citations

Cytosolic calcium oscillators

1988 • 690 citations

myo-Inositol 1,4,5-trisphosphate. A second messenger for the hormonal mobilization of intracellular Ca2+ in liver.

1984 • 567 citations

The second messenger linking receptor activation to internal Ca release in liver

1984 • 557 citations

Use of Manganese to Discriminate Between Calcium Influx and Mobilization From Internal Stores in Stimulated Human Neutrophils

1989 • 520 citations

Intracellular calcium; its universal role as regulator

1984 • 500 citations

Hormonal effects on calcium homeostasis in isolated hepatocytes.

1980 • 441 citations

Fura-2 measurement of cytosolic free Ca2+ in monolayers and suspensions of various types of animal cells.

1987 • 424 citations

Inositol trisphosphate and diacylglycerol as intracellular second messengers in liver

1985 • 419 citations

Changes in free cytosolic Ca2+ in hepatocytes following alpha 1-adrenergic stimulation. Studies on Quin-2-loaded hepatocytes.

1983 • 375 citations

Relationship between inositol polyphosphate production and the increase of cytosolic free Ca2+ induced by vasopressin in isolated hepatocytes.

1984 • 358 citations

Calcium content of mitochondria and endoplasmic reticulum in liver frozen rapidly in vivo

1985 • 356 citations

A novel tumour promoter, thapsigargin, transiently increases cytoplasmic free Ca2+ without generation of inositol phosphates in NG115-401L neuronal cells

1988 • 344 citations

Energy-dependent calcium sequestration activity in rat liver microsomes.

1975 • 342 citations

A Ca2+-insensitive form of fura-2 associated with polymorphonuclear leukocytes. Assessment and accurate Ca2+ measurement.

1987 • 317 citations

Vanadium — an element in search of a role

1980 • 301 citations

A saturable receptor for 32P-inositol-l,4,5-trisphosphate in hepatocytes and neutrophils

1986 • 296 citations

Calcium pools in saponin-permeabilized guinea pig hepatocytes.

1983 • 282 citations

Cystamine induces toxicity in hepatocytes through the elevation of cytosolic Ca2+ and the stimulation of a nonlysosomal proteolytic system.

1986 • 249 citations

Capacitative calcium entry in parotid acinar cells

1989 • 234 citations

2,5‐Di(tert‐butyl)‐1,4‐benzohydroquinone — a novel inhibitor of liver microsomal Ca²⁺ sequestration

1987 • 204 citations

Characterization of inositol 1,4,5-trisphosphate receptors and calcium mobilization in a hepatic plasma membrane fraction.

1988 • 178 citations

Inhibition of ATP-dependent microsomal Ca2+ sequestration during oxidative stress and its prevention by glutathione.

1983 • 176 citations

Inositol 1,3,4,5-Tetrakisphosphate Induces Ca ²⁺ Sequestration in Rat Liver Cells

1988 • 165 citations

Inositol trisphosphate modification of ion transport in rough endoplasmic reticulum.

1985 • 154 citations

The calcium mobilizing and tumor promoting agent, thapsigargin elevates the platelet cytoplasmic free calcium concentration to a higher steady state level. A possible mechanism of action for the tumor promotion

1987 • 144 citations

Calcium ion fluxes induced by the action of α-adrenergic agonists in perfused rat liver

1982 • 144 citations

Neomycin: a specific drug to study the inositol‐phospholipid signalling system?

1986 • 107 citations

Calcium Uptake in Isolated Hepatic Plasma‐Membrane Vesicles

1982 • 107 citations

Receptor-mediated Ca2+ entry: diversity of function and mechanism

1989 • 105 citations

Calcium transport and phosphorylated intermediate of (Ca2+ + Mg2+)-ATPase in plasma membranes of rat liver.

1983 • 100 citations

Novel kinetics of single cell Ca2+ transients in stimulated hepatocytes and A10 cells measured using fura-2 and fluorescent videomicroscopy.

1988 • 93 citations

Effect of cyclic AMP-dependent hormones and Ca2+-mobilizing hormones on the Ca2+ influx and polyphosphoinositide metabolism in isolated rat hepatocytes

1986 • 87 citations

Inhibition of liver-microsome calcium pump by in vivo administration of CCl4, CHCl3 and 1,1-dichloroethylene (vinylidene chloride)

1980 • 87 citations

Properties of energy-dependent calcium transport by rat liver microsomal fraction as revealed by initial-rate measurements

1978 • 86 citations

MgATP-dependent glucose 6-phosphate-stimulated Ca2+ accumulation in liver microsomal fractions. Effects of inositol 1,4,5-trisphosphate and GTP.

1988 • 75 citations

A regulatory calcium-binding site for calcium channel in isolated rat hepatocytes.

1985 • 73 citations

The labelling of polyphosphoinositides with [32P]Pi and the accumulation of inositol phosphates in vasopressin-stimulated hepatocytes

1986 • 70 citations

How far does phospholipase C activity depend on the cell calcium concentration? A study in intact cells

1987 • 69 citations

Stimulation of glycogenolysis in hepatocytes by angiotensin II may involve both calcium release and calcium influx

1983 • 62 citations

Effect of thapsigargin on cytoplasmic Ca2+ and proliferation of human lymphocytes in relations to AIDS

1988 • 55 citations

Some properties of the Ca2+-stimulated ATPase of a rat liver microsomal fraction

1983 • 53 citations

Alterations in inositol phosphate production during oxidative stress in isolated hepatocytes.

1987 • 53 citations

Hormone-induced increase in free cytosolic calcium and glycogen phosphorylase activation in rat hepatocytes incubated in normal and low-calcium media

1985 • 48 citations

The high affinity (Ca2+-Mg2+)-ATPase in liver plasma membranes is a Ca2+ pump. Reconstitution of the purified enzyme into phospholipid vesicles.

1987 • 46 citations

Sustained oscillations in extracellular calcium concentrations upon hormonal stimulation of perfused rat liver

1987 • 40 citations

The calcium pump in rat liver endoplasmic reticulum. Demonstration of the phosphorylated intermediate.

1984 • 37 citations

Effect of thapsigargin on cytoplasmic Ca2+ and proliferation of human lymphocytes in relation to AIDS

1988 • 18 citations

Evidence that guanosine 5′-[γ-thio]triphosphate stimulates plasma membrane Ca2+ inflow when introduced into hepatocytes

1989 • 12 citations