The dopamine D₁ agonist SKF 81297 and the dopamine D₂ agonist LY 171555 act synergistically to stimulate motor behavior of 1‐methyl‐4‐phenyl‐1, 2, 3, 6‐tetrahydropyridine‐lesioned parkinsonian rhesus monkeys

Multiple receptors for dopamine

1979 • 3,739 citations

Uneven Pattern of Dopamine Loss in the Striatum of Patients with Idiopathic Parkinson's Disease

1988 • 1,881 citations

A Clinicopathologic Study of 100 Cases of Parkinson's Disease

1993 • 950 citations

Two dopamine receptors: Biochemistry, physiology and pharmacology

1984 • 939 citations

Recent Advances in the Molecular Biology of Dopamine Receptors

1993 • 768 citations

Review: D1 dopamine receptor—the search for a function: A critical evaluation of the D1/D2 dopamine receptor classification and its functional implications

1987 • 664 citations

The central effects of a novel dopamine agonist

1978 • 646 citations

Anatomy, pigmentation, ventral and dorsal subpopulations of the substantia nigra, and differential cell death in Parkinson's disease.

1991 • 543 citations

D ₁ Dopamine Receptor Activation Required for Postsynaptic Expression of D ₂ Agonist Effects

1987 • 468 citations

Obligatory D-1/D-2 receptor interaction in the generation of dopamine agonist related behaviors

1986 • 321 citations

Inhibition by dopamine of (Na+ + K+)ATPase activity in neostriatal neurons through D1 and D2 dopamine receptor synergism

1990 • 286 citations

Dopamine D-1 receptor agonists combined with the selective D-2 agonist quinpirole facilitate the expression of oral stereotyped behaviour in rats

1987 • 255 citations

Dopamine receptor agonists: selectivity and dopamine D1 receptor efficacy

1990 • 232 citations

Drugs acting on brain dopamine receptors: A conceptual re-evaluation five years after the first selective D-1 antagonist

1989 • 207 citations

Dopaminergic mechanisms and motor function: Characterization of D-1 and D-2 dopamine receptor interactions

1986 • 198 citations

Behavioral correlations of dopamine receptor activation

1983 • 188 citations

Striatal Fos expression is indicative of dopamine D1/D2 synergism and receptor supersensitivity.

1993 • 185 citations

Is stimulation of both D1 and D2 receptors necessary for the expression of dopamine-mediated behaviors?

1988 • 177 citations

A-77636: a potent and selective dopamine D1 receptor agonist with antiparkinsonian activity in marmosets

1992 • 159 citations

Differential involvement of dopamine D-1 and D-2 receptors in the circling behaviour induced by apomorphine, SK & F 38393, pergolide and LY 171555 in 6-hydroxydopamine-lesioned rats

1985 • 152 citations

Dihydrexidine, a full dopamine D1 agonist, reduces MPTP-ioduced parkinsonism in monkeys

1991 • 137 citations

Selective D-1 dopamine receptor agonist treatment of parkinson's disease

1987 • 136 citations

D-1 dopamine receptor stimulation enables the inhibition of nucleus accumbens neurons by a D-2 receptor agonist

1987 • 134 citations

Lisuride, a dopamine agonist in the treatment of early Parkinson's disease

1989 • 131 citations

Differential effects of D ₁ and D ₂ agonists in MPTP‐treated primates

1990 • 99 citations

The Pharmacology of Parkinson's Disease Therapy: An Update

1993 • 88 citations

Bromocriptine in Parkinsonism: long-term treatment, dose response, and comparison with levodopa.

1976 • 85 citations

Motor activity following the administration of selective D-1 and D-2 dopaminergic drugs to normal common marmosets

1991 • 73 citations

The D1 agonist SKF 38393 inhibits the antiparkinsonian activity of the D2 agonist LY 171555 in the MPTP-treated marmoset

1988 • 65 citations

D-2 dopamine autoreceptor selective drugs: Do they really exist?

1990 • 65 citations

Differential efficacies of dopamine D1 receptor agonists for stimulating adenylyl cyclase in squirrel monkey and rat

1993 • 64 citations

Dopamine D1 receptors: efficacy of full (dihydrexidine) vs. partial (SKF38393) agonists in primates vs. rodents

1993 • 62 citations

Grooming and vacuous chewing induced by SK&F 83959, and agonist of dopamine ‘D1-like’ receptors that inhibits dopamine-sensitive adenylyl cyclase

1993 • 56 citations

Antiparkinsonian dopamine agonists: a review of the pharmacokinetics and neuropharmacology in animals and humans

1991 • 54 citations

The D-1 dopamine receptor partial agonist, CY 208–243, exhibits antiparkinsonian activity in the MPTP-treated marmoset

1988 • 52 citations

Lower efficacy of the dopamine D1 agonist, SKF 38393, to stimulate adenylyl cyclase activity in primate than in rodent striatum

1991 • 51 citations

Effect of adding the D1 agonist CY 208–243 to chronic bromocriptine treatment. I: Evaluation of motor parameters in relation to striatal catecholamine content and dopamine receptors

1993 • 46 citations

Effect of D1 receptor stimulation in normal and MPTP monkeys

1989 • 46 citations

The selective dopamine D1 receptor agonist, SKF 81297, stimulates motor behaviour of MPTP-lesioned monkeys

1993 • 38 citations

Enhancement by the D1 dopamine agonist SKF 38393 of specific components of stereotypy elicited by the D2 agonists LY 171555 and RU 24213

1988 • 38 citations

Dopamine D1 receptor agonists display a different intrinsic activity in rat, monkey and human astrocytes

1994 • 38 citations

Relative potency and efficacy of some dopamine agonists with varying selectivities for D1 and D2 receptors in MPTP-induced hemiparkinsonian monkeys.

1993 • 34 citations

Dopamine D1 and D2 receptor interactions in the MPTP-treated marmoset

1992 • 31 citations

Disposition and biotransformation of quinpirole, a new D-2 dopamine agonist antihypertensive agent, in mice, rats, dogs, and monkeys.

1987 • 27 citations

Effects of chronic treatment of MPTP monkeys with bromocriptine alone or in combination with SKF 38393

1990 • 26 citations

Weak Antiparkinsonian Activity of the D1 Agonist C-APB (SKF 82958) and Lack of Synergism With a D2 Agonist in Primates

1992 • 20 citations

Synergistic and persistent interaction between the D2 agonist, bromocriptine, and the D1 selective agonist, CY 208–243

1992 • 15 citations

No direct correlation between behaviorally active doses of the dopamine D₂ agonist LY 171555 and displacement of [¹²³I]IBZM as measured with SPECT in MPTP monkeys

1994 • 10 citations

Effect of PF 10040 on PAF‐induced airway responses in neonatally immunized rabbits

1994 • 6 citations

Unilateral MPTP-Lesioned Monkey as an Animal Model for Parkinson's Disease

1991 • 4 citations