Relative abundance of Alzheimer A beta amyloid peptide variants in Alzheimer disease and normal aging.

Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa

1987 • 11,491 citations

Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein

1984 • 5,166 citations

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

1987 • 4,544 citations

Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

1991 • 4,533 citations

Amyloid plaque core protein in Alzheimer disease and Down syndrome.

1985 • 4,276 citations

A method for the quantitative recovery of protein in dilute solution in the presence of detergents and lipids

1984 • 3,959 citations

The molecular pathology of Alzheimer's disease

1991 • 2,603 citations

Diagnosis of Alzheimer's Disease

1985 • 2,482 citations

Seeding “one-dimensional crystallization” of amyloid: A pathogenic mechanism in Alzheimer's disease and scrapie?

1993 • 2,146 citations

The carboxy terminus of the .beta. amyloid protein is critical for the seeding of amyloid formation: Implications for the pathogenesis of Alzheimer's disease

1993 • 1,951 citations

Amyloid β-peptide is produced by cultured cells during normal metabolism

1992 • 1,888 citations

Isolation and quantification of soluble Alzheimer's β-peptide from biological fluids

1992 • 1,701 citations

A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N–terminus of β–amyloid

1992 • 1,453 citations

Cleavage of Amyloid β Peptide During Constitutive Processing of Its Precursor

1990 • 1,388 citations

Assembly and aggregation properties of synthetic Alzheimer's A4/beta amyloid peptide analogs.

1992 • 982 citations

Structural alterations in the peptide backbone of beta-amyloid core protein may account for its deposition and stability in Alzheimer's disease.

1993 • 775 citations

beta-Amyloid-(1-42) is a major component of cerebrovascular amyloid deposits: implications for the pathology of Alzheimer disease.

1993 • 713 citations

Peptide Compositions of the Cerebrovascular and Senile Plaque Core Amyloid Deposits of Alzheimer′s Disease

1993 • 489 citations

Mass spectrometry of purified amyloid beta protein in Alzheimer's disease.

1992 • 461 citations

Isolation of Low‐Molecular‐Weight Proteins from Amyloid Plaque Fibers in Alzheimer's Disease

1986 • 443 citations

Differences Between Vascular and Plaque Core Amyloid in Alzheimer's Disease

1988 • 348 citations

Protein phosphorylation inhibits production of Alzheimer amyloid beta/A4 peptide.

1993 • 279 citations

Purification, ultrastructure, and chemical analysis of Alzheimer disease amyloid plaque core protein.

1986 • 133 citations

Isolation and Partial Characterization of Neurofibrillary Tangles and Amyloid Plaque Core in Alzheimerʼs Disease

1986 • 128 citations

Brain amyloid in normal aging and cerebral amyloid angiopathy is antigenically related to Alzheimer's disease beta-protein.

1987 • 118 citations

β-Amyloid Protein is Higher in Alzheimerʼs Disease Brains

1993 • 17 citations

Characterization of Amyloid Familial β-Peptide in Familial Alzheimer′s Disease with APP717 Mutations

1993 • 12 citations