GATA Zinc Finger Interactions Modulate DNA Binding and Transactivation

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

An early haematopoietic defect in mice lacking the transcription factor GATA-2

1994 • 1,412 citations

Erythroid differentiation in chimaeric mice blocked by a targeted mutation in the gene for transcription factor GATA-1

1991 • 1,321 citations

The estrogen receptor binds tightly to its responsive element as a ligand-induced homodimer

1988 • 1,233 citations

Requirement of the transcription factor GATA4 for heart tube formation and ventral morphogenesis.

1997 • 1,138 citations

Cloning of cDNA for the major DNA-binding protein of the erythroid lineage through expression in mammalian cells

1989 • 931 citations

The LIM-only protein Lmo2 is a bridging molecule assembling an erythroid, DNA-binding complex which includes the TAL1, E47, GATA-1 and Ldb1/NLI proteins

1997 • 849 citations

GATA-binding transcription factors in hematopoietic cells

1992 • 845 citations

A novel rapid assay for chloramphenicol acetyltransferase gene expression

1987 • 802 citations

GATA-binding transcription factors in hematopoietic cells

1992 • 727 citations

FOG, a Multitype Zinc Finger Protein, Acts as a Cofactor for Transcription Factor GATA-1 in Erythroid and Megakaryocytic Differentiation

1997 • 723 citations

DNA-Binding Specificity of GATA Family Transcription Factors

1993 • 629 citations

Activity and tissue-specific expression of the transcription factor NF-E1 multigene family.

1990 • 629 citations

Targeted disruption of the GATA3 gene causes severe abnormalities in the nervous system and in fetal liver haematopoiesis

1995 • 619 citations

The erythroid-specific transcription factor eryf1: A new finger protein

1989 • 608 citations

DNA-Binding Specificities of the GATA Transcription Factor Family

1993 • 553 citations

Protein motifs 5. Zinc fingers.

1995 • 544 citations

An erythrocyte-specific DNA-binding factor recognizes a regulatory sequence common to all chicken globin genes.

1988 • 518 citations

Zinc fingers

1995 • 501 citations

Allosteric effects of DNA on transcriptional regulators

1998 • 488 citations

Functional Synergy and Physical Interactions of the Erythroid Transcription Factor GATA-1 with the Krüppel Family Proteins Sp1 and EKLF

1995 • 475 citations

Direct interaction of hematopoietic transcription factors PU.1 and GATA-1: functional antagonism in erythroid cells

1999 • 457 citations

NMR Structure of a Specific DNA Complex of Zn-Containing DNA Binding Domain of GATA-1

1993 • 456 citations

The transcription factor GATA6 is essential for early extraembryonic development

1999 • 444 citations

The regulatory gene areA mediating nitrogen metabolite repression in Aspergillus nidulans. Mutations affecting specificity of gene activation alter a loop residue of a putative zinc finger.

1990 • 425 citations

Transcriptional activation and DNA binding by the erythroid factor GF-1/NF-E1/Eryf 1.

1990 • 422 citations

Failure of megakaryopoiesis and arrested erythropoiesis in mice lacking the GATA-1 transcriptional cofactor FOG

1998 • 352 citations

Erythroid-Cell-Specific Properties of Transcription Factor GATA-1 Revealed by Phenotypic Rescue of a Gene-Targeted Cell Line

1997 • 351 citations

Functional analysis and in vivo footprinting implicate the erythroid transcription factor GATA-1 as a positive regulator of its own promoter.

1991 • 333 citations

FOG-2, a Heart- and Brain-Enriched Cofactor for GATA Transcription Factors

1999 • 222 citations

A Palindromic Regulatory Site within Vertebrate GATA-1 Promoters Requires Both Zinc Fingers of the GATA-1 DNA-Binding Domain for High-Affinity Interaction

1996 • 221 citations

end-1 encodes an apparent GATA factor that specifies the endoderm precursor in Caenorhabditis elegans embryos

1997 • 220 citations

nit-2, the Major Nitrogen Regulatory Gene of Neurospora crassa, Encodes a Protein with a Putative Zinc Finger DNA-Binding Domain

1990 • 198 citations

Association of erythroid transcription factors: complexes involving the LIM protein RBTN2 and the zinc-finger protein GATA1.

1995 • 193 citations

Erythroblast cell lines transformed by a temperature-sensitive mutant of avian erythroblastosis virus: A model system to study erythroid differentiation in vitro

1982 • 188 citations

Structure and evolution of a human erythroid transcription factor

1990 • 160 citations

Distinct Roles for the Two cGATA-1 Finger Domains

1992 • 159 citations

NF-E2 and GATA binding motifs are required for the formation of DNase I hypersensitive site 4 of the human beta-globin locus control region.

1995 • 137 citations

Structure and promoter activity of the gene for the erythroid transcription factor GATA-1.

1991 • 129 citations

A small single-"finger" peptide from the erythroid transcription factor GATA-1 binds specifically to DNA as a zinc or iron complex.

1993 • 128 citations

GATA1 and YY1 are developmental repressors of the human epsilon-globin gene.

1995 • 128 citations

Negative Regulation of the Erythropoietin Gene Expression by the GATA Transcription Factors

1997 • 121 citations

The two zinc finger-like domains of GATA-1 have different DNA binding specificities.

1993 • 119 citations

hFOG-2, a Novel Zinc Finger Protein, Binds the Co-repressor mCtBP2 and Modulates GATA-mediated Activation

1999 • 102 citations

trans-Activation of a Globin Promoter in Nonerythroid Cells

1991 • 84 citations

The N-terminal fingers of chicken GATA-2 and GATA-3 are independent sequence-specific DNA binding domains

1997 • 82 citations

Protein-DNA interactions in the epsilon-globin gene silencer.

1993 • 76 citations

2 The regulation of human globin gene expression

1993 • 68 citations

Perturbation of nucleosome structure by the erythroid transcription factor GATA-1

1998 • 62 citations

Conserved Structure, Regulatory Elements, and Transcriptional Regulation from the GATA-1 Gene Testis Promoter

1997 • 54 citations

Involvement of the N-finger in the Self-association of GATA-1

1998 • 52 citations

The solution structure of the N-terminal zinc finger of GATA-1 reveals a specific binding face for the transcriptional co-factor FOG.

1999 • 52 citations

Conserved elements containing NF-E2 and tandem GATA binding sites are required for erythroid-specific chromatin structure reorganization within the human beta-globin locus control region

1998 • 30 citations

The Structure of the Nuclear Factor-κB Protein-DNA Complex Varies with DNA-binding Site Sequence

2000 • 21 citations

Gene Regulatory Proteins and Their Interaction with DNA

1995 • 19 citations

GATA-1 Bends DNA in a Site-independent Fashion

2000 • 18 citations