Phorbol Ester Enhancement of Neurotransmitter Release from Rat Brain Synaptosomes

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

The role of protein kinase C in cell surface signal transduction and tumour promotion

1984 • 7,521 citations

Inositol trisphosphate, a novel second messenger in cellular signal transduction

1984 • 6,088 citations

Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters.

1982 • 4,786 citations

Inositol phospholipids and cell surface receptor function

1975 • 2,458 citations

Changes in the levels of inositol phosphates after agonist-dependent hydrolysis of membrane phosphoinositides

1983 • 1,937 citations

Protein kinase C as a possible receptor protein of tumor-promoting phorbol esters.

1983 • 890 citations

Potentiation of synaptic transmission in the hippocampus by phorbol esters

1986 • 647 citations

Enhancement of calcium current in Aplysia neurones by phorbol ester and protein kinase C

1985 • 476 citations

A rapid method for isolation of synaptosomes on Percoll gradients

1986 • 421 citations

Tritosol: A new scintillation cocktail based on Triton X-100

1975 • 389 citations

Protein kinase C activation of physiological processes in human neutrophils at vanishingly small cytosolic Ca2+ levels

1984 • 334 citations

Multiple phosphorylation sites in protein I and their differential regulation by cyclic AMP and calcium.

1979 • 284 citations

The phorbol ester TPA increases the affinity of exocytosis for calcium in ‘leaky’ adrenal medullary cells

1983 • 269 citations

Calcium/phospholipid regulates phosphorylation of a Mr "87k" substrate protein in brain synaptosomes.

1982 • 257 citations

METABOLISM OF BEDS OF MAMMALIAN CORTICAL SYNAPTOSOMES: RESPONSE TO DEPOLARIZING INFLUENCES

1972 • 215 citations

PHOSPHATIDYLINOSITOL TURNOVER IN RECEPTOR MECHANISM AND SIGNAL TRANSDUCTION

1985 • 207 citations

Stimulus‐secretion coupling processes in brain: analysis of noradrenaline and gamma‐aminobutyric acid release.

1976 • 183 citations

Widespread occurrence of "87 kDa," a major specific substrate for protein kinase C.

1986 • 176 citations

Effects of phorbol ester on catecholamine secretion and protein phosphorylation in adrenal medullary cell cultures.

1985 • 170 citations

Inhibition by calmodulin of calcium/phospholipid-dependent protein phosphorylation.

1984 • 151 citations

EFFECTS OF ELEVATED [K⁺]₀ ON THE RELEASE OF NEUROTRANSMITTERS FROM CORTICAL SYNAPTOSOMES: EFFLUX OR SECRETION?

1978 • 143 citations

Effects of Acetylcholine on Labeling of Phosphatidate and Phosphoinositides by [32P]Orthophosphate in Nerve Ending Fractions of Guinea Pig Cortex

1972 • 125 citations

Phorbol ester and calcium act synergistically to enhance neurotransmitter release by brain neurons in culture

1985 • 123 citations

Phorbol ester facilitates 45Ca accumulation and catecholamine secretion by nicotine and excess K+ but not by muscarine in rat adrenal medulla

1986 • 112 citations

Release of acetylcholine from hippocampal slices by potassium depolarization: dependence on high affinity choline uptake

1974 • 106 citations

Stimulus-Coupled Secretion of γ-Aminobutyric Acid from Rat Brain Synaptosomes

1973 • 103 citations

Phorbol ester, an activator of protein kinase C, enhances calcium-dependent release of sympathetic neurotransmitter

1985 • 83 citations

A phorbol ester and A23187 act synergistically to release acetylcholine from the guinea pig ileum

1984 • 76 citations

A calcium requirement for the phosphatidylinositol response following activation of presynaptic muscarinic receptors

1979 • 63 citations

Receptor-stimulated inositol phospholipid metabolism in the central nervous system

1982 • 56 citations

Enhancement of Ca²⁺‐induced catecholamine release by the phorbol ester TPA in digitonin‐permeabilized cultured bovine adrenal chromaffin cells

1985 • 50 citations

Stimulus-secretion coupling processes in brain: Dependence upon extracellular calcium concentration

1979 • 13 citations

Experimental Galactose Toxicity: Effects on Synaptosomal Phosphatidylinositol Metabolism

1981 • 11 citations