Determination of the genomic organization of human presenilin 1 by fiber-FISH analysis and restriction mapping of cloned DNA

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

1995 • 3,985 citations

The structure of the presenilin 1 (S182) gene and identification of six novel mutations in early onset AD families

1995 • 453 citations

Estimation of the Genetic Contribution of Presenilin-1 and -2 Mutations in a Population-Based Study of Presenile Alzheimer Disease

1998 • 431 citations

Presenilin mutations in Alzheimer's disease

1998 • 191 citations

High-resolution in situ hybridization using DNA halo preparations

1992 • 171 citations

The presenilin genes: a new gene family involved in Alzheimer disease pathology

1996 • 165 citations

High-resolution DNA Fiber-FISH for genomic DNA mapping and colour bar-coding of large genes

1995 • 137 citations

Analysis of the 5′ Sequence, Genomic Structure, and Alternative Splicing of thepresenilin-1Gene (PSEN1) Associated with Early Onset Alzheimer Disease

1997 • 126 citations

Scanning for genes in large genomic regions: cosmid-based exon trapping of multiple exons in a single product

1996 • 28 citations

YAC fragmentation with repetitive and single-copy sequences: detailed physical mapping of the presenilin 1 gene on chromosome 14

1999 • 6 citations