TRAF2 Deficiency Results in Hyperactivity of Certain TNFR1 Signals and Impairment of CD40-Mediated Responses

Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids

1982 • 11,668 citations

Death Receptors: Signaling and Modulation

1998 • 5,873 citations

Apoptosis by Death Factor

1997 • 5,038 citations

Function and Activation of NF-kappaB in the Immune System

1994 • 4,698 citations

OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis

1999 • 3,340 citations

IRS-1-Mediated Inhibition of Insulin Receptor Tyrosine Kinase Activity in TNF-α- and Obesity-Induced Insulin Resistance

1996 • 2,561 citations

A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function

1997 • 2,257 citations

The TNF receptor 1-associated protein TRADD signals cell death and NF-κB activation

1995 • 1,979 citations

TRADD–TRAF2 and TRADD–FADD Interactions Define Two Distinct TNF Receptor 1 Signal Transduction Pathways

1996 • 1,976 citations

Dissection of TNF Receptor 1 Effector Functions: JNK Activation Is Not Linked to Apoptosis While NF-κB Activation Prevents Cell Death

1996 • 1,962 citations

X-linked IAP is a direct inhibitor of cell-death proteases

1997 • 1,961 citations

Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection

1993 • 1,719 citations

Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by osteoprotegerin ligand

1999 • 1,621 citations

CD40 AND CD154 IN CELL-MEDIATED IMMUNITY

1998 • 1,546 citations

IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases

1998 • 1,394 citations

Germline Mutations in the Extracellular Domains of the 55 kDa TNF Receptor, TNFR1, Define a Family of Dominantly Inherited Autoinflammatory Syndromes

1999 • 1,363 citations

The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases

1997 • 1,316 citations

TRAF6 is a signal transducer for interleukin-1

1996 • 1,287 citations

TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signaling

1999 • 1,267 citations

Tumor necrosis factor alpha inhibits signaling from the insulin receptor.

1994 • 1,173 citations

Feedback Inhibition of Macrophage Tumor Necrosis Factor-α Production by Tristetraprolin

1998 • 1,139 citations

TRAF2-Mediated Activation of NF-κB by TNF Receptor 2 and CD40

1995 • 1,046 citations

A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptor

1994 • 1,043 citations

Inflammation, immunoregulation, and inducible nitric oxide synthase

1993 • 877 citations

Characterization of tumor necrosis factor-deficient mice

1997 • 792 citations

Early Lethality, Functional NF-κB Activation, and Increased Sensitivity to TNF-Induced Cell Death in TRAF2-Deficient Mice

1997 • 791 citations

Tumor necrosis factor receptor-associated factors (TRAFs)—a family of adapter proteins that regulates life and death

1998 • 597 citations

Identification of TRAF6, a Novel Tumor Necrosis Factor Receptor-associated Factor Protein That Mediates Signaling from an Amino-terminal Domain of the CD40 Cytoplasmic Region

1996 • 484 citations

Activation of SAPK/JNK by TNF Receptor 1 Through a Noncytotoxic TRAF2-Dependent Pathway

1997 • 454 citations

Involvement of CRAF1, a relative of TRAF, in CD40 signaling

1995 • 454 citations

TRAF2 Is Essential for JNK but Not NF-κB Activation and Regulates Lymphocyte Proliferation and Survival

1997 • 449 citations

Prevention of Constitutive TNF Receptor 1 Signaling by Silencer of Death Domains

1999 • 408 citations

TRAF5, a novel tumor necrosis factor receptor-associated factor family protein, mediates CD40 signaling.

1996 • 339 citations

CD40 and its ligand, an essential ligand-receptor pair for thymus-dependent B-cell activation

1992 • 327 citations

Anatomy of TRAF2

1996 • 302 citations

Identification and functional characterization of DR6, a novel death domain‐containing TNF receptor

1998 • 275 citations

CD40−Tumor Necrosis Factor Receptor-Associated Factor (TRAF) Interactions: Regulation of CD40 Signaling through Multiple TRAF Binding Sites and TRAF Hetero-Oligomerization

1998 • 248 citations

CD40 and Its Ligand in Host Defense

1996 • 236 citations

Presence of a New Conserved Domain in CART1, a Novel Member of the Tumor Necrosis Factor Receptor-associated Protein Family, Which Is Expressed in Breast Carcinoma

1995 • 229 citations

Functions of CD40 and Its Ligand, gp39 (CD40L)

2017 • 212 citations

A novel member of the TRAF family of putative signal transducing proteins binds to the cytosolic domain of CD40

1995 • 177 citations

THE MAMMALIAN CELL-VIRUS RELATIONSHIP

1959 • 176 citations

CD40-CD40 ligand interactions are critical in T-B cooperation but not for other anti-viral CD4+ T cell functions.

1996 • 149 citations

Journey from cachexia to obesity by TNF

1997 • 137 citations

Tumor necrosis factor (TNF-α) and lymphotoxin (TNF-β)

1992 • 136 citations

Virus-induced autoantibody response to a transgenic viral antigen

1990 • 130 citations

Listeriosis in p47phox−/− and TRp55−/− Mice: Protection Despite Absence of ROI and Susceptibility Despite Presence of RNI

1997 • 130 citations

Functions of CD40 and Its Ligand, gp39 (CD40L)

1996 • 126 citations

Two differently regulated nuclear factor κB activation pathways triggered by the cytoplasmic tail of CD40

1999 • 98 citations

Tumor necrosis factor (TNF-α) and lymphotoxin (TNF-β)

1992 • 97 citations

Determination of total and merecaptothanol-resistant antibody in the same serum sample.

1970 • 89 citations

Specificities of CD40 signaling: Involvement of TRAF2 in CD40-induced NF-κB activation and intercellular adhesion molecule-1 up-regulation

1999 • 87 citations

Recent advances in tumor necrosis factor and CD40 signaling

1996 • 85 citations

Analysis of the kinetics of antiviral memory T help in vivo: characterization of short‐lived cross‐reactive T help

1990 • 55 citations