Chemokine-enhanced migration of human peripheral blood mononuclear cells is antagonized by interferon beta-1b through an effect on matrix metalloproteinase-9

Matrix metalloproteinases and their inhibitors in connective tissue remodeling

1991 • 3,309 citations

Intramuscular interferon beta‐1a for disease progression in relapsing multiple sclerosis

1996 • 2,410 citations

Interferon beta‐1b is effective in relapsing‐remitting multiple sclerosis

1993 • 2,032 citations

Interferon beta‐1b is effective in relapsing‐remitting multiple sclerosis

1993 • 1,908 citations

The matrix‐degrading metalloproteinases

1992 • 1,383 citations

Selective attraction of monocytes and T lymphocytes of the memory phenotype by cytokine RANTES

1990 • 1,378 citations

The Neutrophil-Activating Protein (NAP-1) Is Also Chemotactic for T Lymphocytes

1989 • 1,060 citations

Interferon beta‐lb in the treatment of multiple sclerosis

1995 • 899 citations

T-cell adhesion induced by proteoglycan-immobilized cytokine MIP-lβ

1993 • 896 citations

Human macrophage inflammatory protein alpha (MIP-1 alpha) and MIP-1 beta chemokines attract distinct populations of lymphocytes.

1993 • 530 citations

T cell gelatinases mediate basement membrane transmigration in vitro.

1995 • 507 citations

Astrocyte expression of mRNA encoding cytokines IP‐10 and JE/MCP‐1 in experimental autoimmune encephalomyelitis

1993 • 496 citations

An important role for the chemokine macrophage inflammatory protein-1 alpha in the pathogenesis of the T cell-mediated autoimmune disease, experimental autoimmune encephalomyelitis.

1995 • 487 citations

The Family of Matrix Metalloproteinases^a

1994 • 437 citations

Controlled recruitment of monocytes and macrophages to specific organs through transgenic expression of monocyte chemoattractant protein-1.

1995 • 389 citations

Chemokine expression in murine experimental allergic encephalomyelitis

1995 • 363 citations

Interferon β‐1b decreases the migration of T lymphocytes in vitro: Effects on matrix metalloproteinase‐9

1996 • 363 citations

Monocyte chemotactic protein-1 (MCP-1), -2, and -3 are chemotactic for human T lymphocytes.

1995 • 350 citations

Chemokines and T lymphocyte activation: I. Beta chemokines costimulate human T lymphocyte activation in vitro.

1996 • 316 citations

Interferon beta‐1b inhibits gelatinase secretion and in vitro migration of human T cells: A possible mechanism for treatment efficacy in multiple sclerosis

1996 • 302 citations

Matrix Metalloproteinases in the Normal Human Central Nervous System, Microglial Nodules, and Multiple Sclerosis Lesions

1996 • 290 citations

Gelatinase in the cerebrospinal fluid of patients with multiple sclerosis and other inflammatory neurological disorders

1992 • 286 citations

Effect of steroids on CSF matrix metalloproteinases in multiple sclerosis

1996 • 278 citations

Interferon β decreases T cell activation and interferon γ production in multiple sclerosis

1993 • 264 citations

Purification and identification of 91‐kDa neutrophil gelatinase

1991 • 259 citations

The Expression of Tissue-type Plasminogen Activator, Matrix Metalloproteases and Endogenous Inhibitors in the Central Nervous System in Multiple Sclerosis

1996 • 247 citations

Localization of monocyte chemoattractant peptide-1 expression in the central nervous system in experimental autoimmune encephalomyelitis and trauma in the rat.

1996 • 244 citations

Interferon beta induces interleukin‐10 expression: Relevance to multiple sclerosis

1996 • 240 citations

Chemokines regulate T cell adherence to recombinant adhesion molecules and extracellular matrix proteins.

1996 • 211 citations

Cytokine and chemokine regulation of proMMP-9 and TIMP-1 production by human peripheral blood lymphocytes.

1997 • 205 citations

The C–C Chemokine MCP-1 Differentially Modulates the Avidity of β1 and β2 Integrins on T Lymphocytes

1996 • 193 citations

Purification and Characterization of Two Related but Distinct Metalloproteinase Inhibitors Secreted by Bovine Aortic Endothelial Cells

1989 • 193 citations

Attenuation of Astroglial Reactivity by Interleukin-10

1996 • 182 citations

Stimulus specificity of matrix metalloproteinase dependence of human T cell migration through a model basement membrane.

1996 • 173 citations

Management of patients receiving interferon beta-1b for multiple sclerosis

1996 • 171 citations

Regulation of monocyte integrin expression by beta-family chemokines.

1994 • 169 citations

Autoimmune Pathogenesis of Multiple Sclerosis: Role of Autoreactive T Lymphocytes and New Immunotherapeutic Strategies

1997 • 159 citations

Neutrophil infiltration, glial reaction, and neurological disease in transgenic mice expressing the chemokine N51/KC in oligodendrocytes.

1996 • 159 citations

Interferon-β inhibits progression of relapsing-remitting experimental autoimmune encephalomyelitis

1996 • 153 citations

Microglial production of TNF-alpha is induced by activated T lymphocytes. Involvement of VLA-4 and inhibition by interferonbeta-1b.

1997 • 139 citations

Macrophage inflammatory protein-1α in the cerebrospinal fluid of patients with multiple sclerosis and other inflammatory neurological diseases

1995 • 133 citations

To stick or not to stick: the new leukocyte homing paradigm

1996 • 125 citations

Mechanisms of Glioma Invasion: Role of Matrix-Metalloproteinases

1997 • 120 citations

Interfer beta augments supperssor cell function in multiple sclerosis

1990 • 120 citations

Interferon-beta sub 1b treatment decreases tumor necrosis factor-alpha and increases interleukin-6 production in multiple sclerosis

1996 • 119 citations

Expression of the chemokine N51/KC in the thymus and epidermis of transgenic mice results in marked infiltration of a single class of inflammatory cells.

1994 • 117 citations

Circulating adhesion molecules and inflammatory mediators in demyelination

1995 • 113 citations

In vitro and in vivo inhibition of mitogen‐driven T‐cell activation by recombinant interferon beta

1993 • 91 citations

Fibronectin and fibronectin fragments modulate the expression of proteinases and proteinase inhibitors in human periodontal ligament cells

1996 • 85 citations

The role of autoimmune T lymphocytes in the pathogenesis of multiple sclerosis

1995 • 76 citations

Regulation and function of central nervous system chemokines

1995 • 75 citations

Suppression of Experimental Allergic Encephalomyelitis by Interferon

1982 • 71 citations

Do Chemokines Mediate Inflammatory Cell Invasion of the Central Nervous System Parenchyma?

1994 • 68 citations

Mechanisms of action of interferon-? in multiple sclerosis

1996 • 68 citations

Functional specialization of fibronectin-binding beta 1-integrins in T lymphocyte migration.

1994 • 65 citations

Regulation of extracellular matrix degradation by cell—extracellular matrix interactions

1990 • 63 citations

Beta-interferon and multiple sclerosis

1997 • 60 citations

Chemokines and T lymphocyte activation: II. Facilitation of human T cell trafficking in severe combined immunodeficiency mice.

1996 • 60 citations

Mechanisms of action of interferon-β in multiple sclerosis

1996 • 51 citations

Familial hemiplegic migraine versus migraine with prolonged aura

1995 • 46 citations

Chemotaxis of T lymphocytes on extracellular matrix proteins Analysis of the in vitro method to quantitate chemotaxis of human T cells

1995 • 45 citations

Regulation of matrix metalloproteinases following cellular transformation

1996 • 35 citations

Interferon in Experimental Autoimmune Encephalomyelitis (EAE): Effects of Exogeneous Interferon on the Antigen-Enhanced Adoptive Transfer of EAE

1985 • 27 citations

Fibronectin induces phosphorylation of a 120‐kDa protein and synergizes with the T cell receptor to activate cytotoxic T cell clones

1995 • 26 citations

Chemokines and Human Infection

1995 • 15 citations

Treatment of relapsing-remitting multiple sclerosis with natural interferon beta: a multicenter, randomized clinical trial.

1995 • 15 citations