The metabolism of homocysteine: pathways and regulation

Homocysteine and Cardiovascular Disease

1998 • 2,177 citations

Methionine metabolism in mammals

1990 • 1,463 citations

Disorders of transsulfuration

1989 • 1,053 citations

The pathogenesis of homocysteinemia: interruption of the coordinate regulation by S-adenosylmethionine of the remethylation and transsulfuration of homocysteine

1992 • 562 citations

Labile methyl balances for normal humans on various dietary regimens

1975 • 492 citations

Betaine-homocysteine methyltransferase: organ distribution in man, pig and rat and subcellular distribution in the rat

1991 • 207 citations

Transsulfuration depends on heme in addition to pyridoxal 5'-phosphate. Cystathionine beta-synthase is a heme protein.

1994 • 181 citations

Allosteric inhibition of methylenetetrahydrofolate reductase by adenosylmethionine. Effects of adenosylmethionine and NADPH on the equilibrium between active and inactive forms of the enzyme and on the kinetics of approach to equilibrium.

1987 • 159 citations

Methionine metabolism in mammals: Regulatory effects of S-adenosylhomocysteine

1974 • 98 citations

[1-13C; methyl-2H3]methionine kinetics in humans: methionine conservation and cystine sparing

1990 • 88 citations

Homocysteine catabolism: levels of 3 enzymes in cultured human vascular endothelium and their relevance to vascular disease

1992 • 55 citations

Determination of in vivo protein binding of homocysteine and its relation to free homocysteine in the liver and other tissues of the rat.

1986 • 51 citations

Regulation of methionine metabolism: Effects of nitrous oxide and excess dietary methionine

1994 • 48 citations

Rat liver cytosolic 4 S polycyclic aromatic hydrocarbon-binding protein is glycine N-methyltransferase.

1994 • 47 citations

Deleted Work

1955 • 0 citations