Transsulfuration depends on heme in addition to pyridoxal 5'-phosphate. Cystathionine beta-synthase is a heme protein.

The Metabolic Basis of Inherited Disease.

1988 • 7,933 citations

A rapid, sensitive, and versatile assay for protein using Coomassie brilliant blue G250

1977 • 2,970 citations

Simultaneous determination of hemes a, b, and c from pyridine hemochrome spectra

1987 • 885 citations

Activation of cystathionine synthase by adenosylmethionine and adenosylethionine

1975 • 277 citations

Rat cystathionine beta-synthase. Gene organization and alternative splicing.

1992 • 144 citations

Sulfur donor ligand binding to ferric cytochrome P-450-CAM and myoglobin. Ultraviolet-visible absorption, magnetic circular dichroism, and electron paramagnetic resonance spectroscopic investigation of the complexes.

1982 • 140 citations

Human cystathionine β-synthase cDNA: sequence, alternative splicing and expression in cultured cells

1993 • 108 citations

Screening for mutations by expressing patient cDNA segments inE. coli: Homocystinuria due to cystathionine β-synthase deficiency

1992 • 96 citations

Purification and properties of cystathionine beta-synthase from human liver. Evidence for identical subunits.

1978 • 91 citations

Inactivation of betaine-homocysteine methyltransferase by adenosylmethionine and adenosylethionine

1984 • 78 citations

Determination of heme a concentration in cytochrome preparations by hemochromogen method

1965 • 77 citations

Hemoprotein H-450 Identified as a Form of Cytochrome P-450 Having an Endogenous Ligand at the 6th Coordination Position of the Heme

1984 • 69 citations

Bacterial l-serine dehydratases: a new family of enzymes containing iron-sulfur clusters

1993 • 67 citations

Mechanism of action of cystathionine synthase

1982 • 63 citations

Biosynthesis and proteolytic activation of cystathionine beta-synthase in rat liver.

1984 • 59 citations

Cystathionine β-synthase from human liver: Improved purification scheme and additional characterization of the enzyme in crude and pure form

1983 • 44 citations

Rat cystathionine β-synthase: Expression of four alternatively spliced isoforms in transfected cultured cells

1992 • 38 citations

[69] Fluorometric determination of pyridoxal phosphate in enzymes

1979 • 38 citations

Studies on Cystathionine Synthetase Characteristics of Purified Rat Liver Enzyme

1971 • 34 citations

[10] Pyridoxal phosphate-binding site in enzymes: Reduction and comparison of sequences

1984 • 32 citations

Porphyrin and Heme Biosynthesis from Endogenous and Exogenous δ-Aminolevulinic Acid inEscherichia coli, Pseudomonas aeruginosa,andAchromobacter metalcaligenes

1971 • 31 citations

Isolation and properties of a new, soluble, hemoprotein (H-450) from pig liver

1976 • 23 citations

Molecular Cloning and Sequence Analysis of cDNA Coding for Rat Liver Hemoprotein H-4501

1990 • 21 citations

The pyridoxal-phosphate-dependent enzymes exclusively catalyzing reactions of β-replacement

1976 • 20 citations

Depletion of cultured human fibroblasts of pyridoxal 5′-phospate: Effect on activities of aspartate aminotransferase, alanine aminotransferase, and cystathionine β-synthase

1980 • 16 citations

Spectral Similarities between “H-450” and Cytochrome P-450

1984 • 15 citations

Immunological characterization of cytochrome H-450 in rat tissues.

1982 • 11 citations

Reaction of dithionite and bisulfite with pyridoxal and pyridoxal enzymes

1969 • 8 citations

Isolation and characterization of respiratory-deficient mutants of Escherichia coli K-12

1988 • 7 citations