Liver microsomal polypeptides from Fischer-344 rats affected by age, sex, and xenobiotic induction

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Methods in Enzymology , Vol

1966 • 26,261 citations

High resolution two-dimensional electrophoresis of proteins.

1975 • 19,515 citations

Pharmacological implications of microsomal enzyme induction.

1967 • 2,883 citations

Separation and characterization of highly purified forms of liver microsomal cytochrome P-450 from rats treated with polychlorinated biphenyls, phenobarbital, and 3-methylcholanthrene.

1979 • 576 citations

Microsomes and Drug Oxidations

1970 • 463 citations

CORRELATED MORPHOMETRIC AND BIOCHEMICAL STUDIES ON THE LIVER CELL

1969 • 317 citations

Regulation of three forms of cytochrome P-450 and epoxide hydrolase in rat liver microsomes. Effects of age, sex, and induction.

1981 • 304 citations

Hepatic microsomal cytochrome P-450 from rats treated with isosafrole. Purification and characterization of four enzymic forms.

1980 • 286 citations

The resolution and reconstitution of the liver microsomal hydroxylation system

1974 • 223 citations

MORPHOLOGICAL CHANGES IN THE LIVER ACCOMPANYING STIMULATION OF MICROSOMAL DRUG METABOLIZING ENZYME ACTIVITY BY PHENOBARBITAL, CHLORDANE, BENZPYRENE OR METHYL-CHOLANTHRENE IN RATS.

1965 • 210 citations

Liver microsomal expoxide hydrase. Solubilization, purification, and characterization.

1975 • 170 citations

Sex-dependent differences in drug metabolism in the rat. I. Temporal changes in microsomal drug-metabolizing system of the liver during sexual maturation.

1974 • 100 citations

Age-related changes in drug disposition.

1978 • 97 citations

Sex difference in the O-dealkylation activity of 7-hydroxycoumarin O-alkyl derivatives in liver microsomes of rats

1980 • 92 citations

Studies on microsomal hydroxylation and the demonstration of a new carbon monoxide binding pigment in liver microsomes

1968 • 86 citations

Liver endoplasmic reticulum polypeptides resolved by two-dimensional gel electrophoresis

1980 • 79 citations

Induction of hepatic mixed function oxidases in senescent rodents

1978 • 77 citations

Influence of aging and induction on rat liver and kidney microsomal mixed function oxidase systems

1980 • 68 citations

Effects of aging and phenobarbital on the rat liver microsomal drug-metabolizing system

1981 • 68 citations

Induction of the hepatic cytochrome P-450-dependent mono-oxygenase system in young and geriatric rats

1980 • 49 citations

Induction of hepatic mixed function oxidases in senescent rodents—II. Effect of polychlorinated biphenyls

1978 • 40 citations

Ectopic arrhytmia provoking action of aldosterone

1962 • 27 citations

Proalbumin is bound to the membrane of rat liver smooth microsomes

1980 • 22 citations

The induction of liver microsomal proteins by 3-methylcholanthrene in rats of different age, sex and strain

1980 • 18 citations

Is steroid-16α-hydroxylase supported by more than one monooxygenase?

1978 • 15 citations