Three T cell hybridomas do not contain detectable heavy chain variable gene transcripts.

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I

1977 • 12,015 citations

Purification of Biologically Active Globin Messenger RNA by Chromatography on Oligothymidylic acid-Cellulose

1972 • 6,922 citations

Analysis of gene control signals by DNA fusion and cloning in Escherichia coli

1980 • 2,499 citations

A colony bank containing synthetic CoI EI hybrid plasmids representative of the entire E. coli genome

1976 • 1,313 citations

Plasmid screening at high colony density

1980 • 1,100 citations

An immunoglobulin heavy chain variable region gene is generated from three segments of DNA: VH, D and JH

1980 • 872 citations

Two types of somatic recombination are necessary for the generation of complete immunoglobulin heavy-chain genes

1980 • 803 citations

Efficient transcription of RNA into DNA by avian sarcoma virus polymerase

1976 • 688 citations

Heavy chain variable region contribution to the NPb family of antibodies: somatic mutation evident in a γ2a variable region

1981 • 677 citations

A bacterial clone synthesizing proinsulin.

1978 • 515 citations

Sequences of mouse immunoglobulin light chain genes before and after somatic changes

1978 • 495 citations

A single VH gene segment encodes the immune response to phosphorylcholine: Somatic mutation is correlated with the class of the antibody

1981 • 470 citations

THE ORGANIZATION, EXPRESSION, AND EVOLUTION OF ANTIBODY GENES AND OTHER MULTIGENE FAMILIES

1975 • 446 citations

Sequence of a mouse germ-line gene for a variable region of an immunoglobulin light chain.

1978 • 419 citations

The expression of three abundance classes of messenger RNA in mouse tissues

1976 • 401 citations

Synthesis of double-stranded DNA complementary to lysozyme, ovomucoid, and ovalbumin mRNAs. Optimization for full length second strand synthesis by Escherichia coli DNA polymerase I.

1978 • 395 citations

β ₂ -Microglobulin—A Free Immunoglobulin Domain

1972 • 387 citations

Antibody diversity: Somatic hypermutation of rearranged VH genes

1981 • 334 citations

Identification of D segments of immunoglobulin heavy-chain genes and their rearrangement in T lymphocytes

1981 • 327 citations

Complete amino acid sequence of an HLA-DR antigen-like beta chain as predicted from the nucleotide sequence: similarities with immunoglobulins and HLA-A, -B, and -C antigens.

1982 • 320 citations

Three cDNA clones encoding mouse transplantation antigens: Homology to immunoglobulin genes

1981 • 287 citations

Synthesis of full length cDNAs from four partially purified oviduct mRNAs.

1978 • 279 citations

Amino acid sequence of homogeneous antibodies to dextran and DNA rearrangments in heavy chain V-region gene segments

1980 • 272 citations

Antigen-Binding, Idiotypic T-Lymphocyte Receptors

1977 • 230 citations

3′-End labeling of DNA with [α-32P] cordycepin-5′-triphosphate

1980 • 219 citations

Antigen Receptors of T Helper Cells

1977 • 200 citations

Two Different V_H Gene Products Make Up the T‐Cell Receptors

1976 • 179 citations

Methylmercury hydroxide enhancement of translation and transcription of ovalbumin and conalbumin mRNA's.

1979 • 175 citations

Expression of the immunoglobulin C mu gene in mouse T and B lymphoid and myeloid cell lines.

1980 • 170 citations

Alpha chain of HLA-DR transplantation antigens is a member of the same protein superfamily as the immunoglobulins

1982 • 168 citations

Immunoglobulin messenger RNAs in murine cell lines that have characteristics of immature B lymphocytes

1979 • 158 citations

Diversity of germ-line immunoglobulin VH genes

1981 • 140 citations

The heavy chain of human histocompatibility antigen HLA-B7 contains an immunoglobulin-like region

1979 • 134 citations

The synthesis of oligodeoxyprimidines on a polymer support

1980 • 129 citations

Complexity and specificity of polysomal poly(A⁺) RNA in mouse tissues

1976 • 128 citations

Mechanisms of regulation of cell-mediated immunity. IV. Azobenzenearsonate-specific suppressor factor(s) bear cross-reactive idiotypic determinants the expression of which is linked to the heavy-chain allotype linkage group of genes.

1979 • 121 citations

Organization and evolution of immunoglobulin VH gene subgroups.

1982 • 114 citations

Somatic rearrangements forming active immunoglobulin mu genes in B and T lymphoid cell lines.

1980 • 101 citations

T-cell idiotypes are linked to immunoglobulin heavy chain genes

1976 • 101 citations

Simple DNA sequences in homologous flanking regions near immunoglobulin V_Hgenes: a role in gene interaction?

1982 • 99 citations

The amino-terminal sequence of human fibroblast interferon as deduced from reverse transcripts obtained using synthetic oligonucleotide primers

1980 • 93 citations

Transcripts of the immunoglobulin C mu gene vary in structure and splicing during lymphoid development.

1980 • 89 citations

Antigen specific T-cell helper factor cross reacts idiotypically with antibodies of the same specificity

1979 • 87 citations

Idiotypic analysis of lymphocytes in vitro. II. Genetic control of T-helper cell responsiveness to anti-idiotypic antibody.

1976 • 84 citations

The T suppressor cell alloantigen Tsud maps near immunoglobulin allotype genes and may be an heavy chain constant-region marker on a T cell receptor.

1981 • 84 citations

Mouse immunoglobulin genes: a bacterial plasmid containing the entire coding sequence for a pre-γ 2a heavy chain

1980 • 81 citations

Simultaneous expression of immunoglobulin mu and delta heavy chains by a cloned B-cell lymphoma: a single copy of the VH gene is shared by two adjacent CH genes.

1982 • 79 citations

The nucleotide sequences of rearranged and germline immunoglobulin VH genes of a mouse myeloma MC101 and evolution of VH genes in mouse.

1982 • 76 citations

The use of zinc bromide for removal of dimethoxytrityl ethers from deoxynucleosides

1980 • 73 citations

Helper and killer T cells do not express B cell immunoglobulin joining and constant region gene segments.

1980 • 73 citations

An immunoglobulin heavy-chain gene is altered in two T-cell clones

1980 • 72 citations

Nucleotide sequence of immunoglobulin heavy chain joining segments between translocated VH and mu constant regions genes.

1980 • 69 citations

Mouse heavy chain variable regions: nucleotide sequence of a germ-line V_Hgene segment

1981 • 68 citations

Immunoglobulin heavy chain gene rearrangement and transcription in murine T cell hybrids and T lymphomas.

1982 • 62 citations

Somatic Mutation in Genes for the Variable Portion of the Immunoglobulin Heavy Chain

1982 • 60 citations

The immunoglobulin μ constant region gene is expressed in mouse thymocytes

1980 • 58 citations

T and B cells that recognize the same antigen do not transcribe similar heavy chain variable region gene segments.

1983 • 54 citations

Reconstitution of antigen-specific suppressor activity with translation products of mRNA

1982 • 51 citations

Antigen-specific, H-2-restricted helper T cell hybridomas.

1982 • 44 citations

The preparation and screening of a cDNA clone bank

1981 • 43 citations

Two distinct allotypic determinants on the antigen-specific suppressor and enhancing T cell factors that are encoded by genes linked to the immunoglobulin heavy chain locus.

1982 • 39 citations

A T15-idiotype-positive T suppressor hybridoma does not use the T15 VH gene segment.

1982 • 36 citations

A mature T lymphocyte subpopulation marker closely linked to the Ig‐1 allotype C_H locus

1979 • 31 citations

The isolation of cloned cDNA sequen which are differentially expressed in human lymphocytes and fibroblasts

1980 • 29 citations

Cloning and sequence of the cDNA corresponding to the variable region of immunoglobulin heavy chain MPC11

1980 • 28 citations

A family of T-cell alloantigens linked to Igh-1

1981 • 28 citations

A search for messenger RNA molecules bearing immunoglobulin VH nucleotide sequences in T cells.

1982 • 27 citations

The T-Cell Receptor Problem

1981 • 22 citations

Constant region determinants on the antigen-binding chain of the suppressor T-cell factor

1982 • 21 citations

Immunoglobulin idiotopes expressed by T cells. I. Expression of distinct idiotopes detected by monoclonal antibodies on antigen-specific suppressor T cells.

1982 • 20 citations

Immunoglobulin gene rearrangements in normal mouse B cells.

1982 • 19 citations

T‐Cell Receptor Idiotypes

1980 • 18 citations

Immunoglobulin Genes Undergo Multiple Sequence Rearrangements during Differentiation

1981 • 14 citations

The 5936 Ig‐Idiotype(s): Genetic Linkage to Ig‐C^H Loci, T‐Cell Dependence of Synthesis and Possible Specificities

1981 • 10 citations

Immunoglobulin Gene Rearrangements in Normal Mouse B Cells

1982 • 5 citations

Characterization of Antigen-Specific Suppressor Factors from T Cell Hybridomas

1982 • 4 citations

Cloned T Cells as a Tool for Molecular Geneticists: Approaches to Cloning Genes Which Encode T Cell Antigen Receptors

1982 • 3 citations