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Characterization of Antigen-Specific Suppressor Factors from T Cell Hybridomas

Data up to Jan 2025

Published1982
Citations4
References44

Total Citations Per Year

Abstract

References (44)

Continuous cultures of fused cells secreting antibody of predefined specificity

1975 • 17,037 citations

Properties of the antigen-specific suppressive T-cell factor in the regulation of antibody response of the mouse. IV. Special subregion assignment of the gene(s) that codes for the suppressive T-cell factor in the H-2 histocompatibility complex.

1976 • 376 citations

A Single Major Pathway of T‐Lymphocyte Interactions in Antigen‐Specific Immune Suppression

1981 • 281 citations

Polymorphism of the major envelope glycoprotein (gp70) of murine C-type viruses: virion associated and differentiation antigens encoded by a multi-gene family

1977 • 260 citations

Antigen-reactive T cell clones. I. Transcomplementing hybrid I-A-region gene products function effectively in antigen presentation.

1980 • 252 citations

GENETIC CONTROL OF IMMUNE RESPONSES IN VITRO

1974 • 235 citations

Quantitation and Cloning of Cytolytic T Lymphocytes and their Precursors

1980 • 213 citations

Regulation by the H-2 gene complex of macrophage-lymphoid cell interactions in secondary antibody responses in vitro.

1976 • 176 citations

Shared idiotypic determinants on antibodies and T-cell-derived suppressor factor specific for the random terpolymer L-glutamic acid60-L-alanine30-L-tyrosine10.

1979 • 142 citations

T-cell lines producing antigen-specific suppressor factor

1978 • 137 citations

Immunosuppressive Factor(s) Extracted from Lymphoid Cells of Nonresponder Mice Primed with L-Glutamic Acid60-L-Alanine30-L-Tyrosine10 (GAT) I. Activity and Antigenic Specificity

1976 • 135 citations

Immunosuppressive factor(s) extracted from lymphoid cells of nonresponder mice primed with L-glutamic acid60-L-alanine30-L-tyrosine10 (GAT) III. Immunochemical properties of the GAT-specific suppressive factor.

1977 • 123 citations

Immunosuppressive Factor(s) Extracted from Lymphoid Cells of Nonresponder Mice Primed with L-Glutamic Acid60-L-Alanine30-L-Tyrosine10 (GAT)

1976 • 121 citations

T-lymphocyte-enriched murine peritoneal exudate cells. II. Genetic control of antigen-induced T-lymphocyte proliferation.

1976 • 120 citations

Antibody to Leukemia Virus: Widespread Occurrence in Inbred Mice

1974 • 120 citations

Specific suppressive factors produced by hybridomas derived from the fusion of enriched suppressor T cells and a T lymphoma cell line

1978 • 119 citations

Suppression of antibody and T cell proliferative responses to L-glutamic acid60-L-alanine30-L-tyrosine10 by a specific monoclonal T cell factor.

1980 • 109 citations

GENETIC CONTROL OF IMMUNE RESPONSES IN VITRO

1973 • 108 citations

Genetic control of specific immune suppression. II. H-2-linked dominant genetic control of immune suppression by the random copolymer L-glutamic acid50-L-tyrosine50 (GT).

1975 • 105 citations

Antigen-specific t lymphocyte clones. II. Purifcation and biological characterization of an antigen-specific suppressive protein synthesized by cloned T cells

1981 • 103 citations

Hapten-specific T cell responses to 4-hydroxy-3-nitrophenyl acetyl. V. Role of idiotypes in the suppressor pathway.

1980 • 102 citations

Immunosuppressive factor(s) specific for L-glutamic acid50-L-tyrosine50 (GT). III. Generation of suppressor T cells by a suppressive extract derived from GT-primed lymphoid cells.

1977 • 89 citations

Use of cloned populations of mouse lymphocytes to analyze cellular differentiation

1981 • 88 citations

Genetic control of specific immune suppression. I. Experimental conditions for the stimulation of suppressor cells by the copolymer L-glutamic acid50-L-tyrosine50 (GT) in nonresponder BALB/c mice.

1975 • 84 citations

GENETIC CONTROL OF IMMUNE RESPONSES IN VITRO

1973 • 76 citations

Production of an H–2-related suppressor factor by a hybrid T-cell line

1979 • 75 citations

Presence of interchain disulfide bonds between two gene products that compose the secreted form of an antigen-specific suppressor factor.

1981 • 71 citations

Regulation of immune responses by I-J gene products. I. Production and characterization of anti-I-J monoclonal antibodies.

1981 • 69 citations

Immunosuppressive factor(s) extracted from lymphoid cells of nonresponder mice primed with L-glutamic acid60-L-alanine30-L-tyrosine10 (GAT) II. Cellular source and effect on responder and nonresponder mice.

1977 • 65 citations

Antigen- and receptor-driven regulatory mechanisms. VII. H-2-restricted anti-idiotypic suppressor factor from efferent suppressor T cells.

1981 • 62 citations

Selective suppression of the major idiotypic component of an antihapten response by soluble T cell-derived factors with idiotypic or anti-idiotypic receptors.

1980 • 49 citations

Antigen-Specific T Cell-Mediated Suppression: III. Induction of Antigen-Specific Suppressor T Cells (TS2) in L-Glutamic Acid60-L-Alanine30-L-Tyrosine10 (GAT) Responder Mice by Nonresponder-Derived GAT-Suppressor Factor (GAT-TSF)

1978 • 46 citations

Immunosuppressive factors from lymphoid cells of nonresponder mice primed with L-glutamic acid60-L-alanine30-L-tyrosine10. IV. Lack of strain restrictions among allogeneic, nonresponder donors and recipients.

1978 • 46 citations

Purification and characterization of a monoclonal T-cell suppressor factor specific for poly(LGlu60LAla30LTyr10).

1982 • 42 citations

Secondary antibody responses in vitro to L-glutamic acid60-L-alanine30-L-tyrosine10 (GAT) by (responder X nonresponder)F1 spleen cells stimulated by parental GAT-macrophages.

1977 • 35 citations

Antigen-specific suppressor T cell interactions. I. Induction of an MHC-restricted suppressor factor specific for L-glutamic acid50-L-tyrosine50.

1982 • 29 citations

Immunosuppressive factor(s) from lymphoid cells of nonresponder mice primed with L-glutamic acid60-L-alanine30-L-tyrosine10 (GAT). V. Inhibition of T cell proliferative responses.

1980 • 28 citations

H-2-linked Ir gene control of T cell proliferative responses to the synthetic terpolymer L-glutamic acid60-L-alanine30-L-tyrosine10 (GAT). I. Requirements for T cell activation in responder and nonresponder mice.

1980 • 27 citations

Immunosuppressive factor(s) specific for L‐glutamic acid50‐L‐tyrosine50 IV. In vitro activity and immunochemical properties

1977 • 27 citations

Suppressor T-cell activity in responder x nonresponder (C57BL/10 x DBA/1)F(1) spleen cells responsive to l-glutamic acid(60)-L-alanine(30)-L-tyrosine (10)

1978 • 24 citations

Antigen-Specific T Cell-Mediated Suppression

1978 • 17 citations

Antigen-specific T cell-mediated suppression. V. H-2-linked genetic control of distinct antigen-specific defects in the production and activity of L-glutamic acid50-L-tyrosine50 suppressor factor.

1980 • 14 citations

Genetic analysis of immune suppression

1981 • 13 citations

Amplified env and gag products on AKR cells. Origin from different murine leukemia virus genomes.

1980 • 12 citations

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