Estrogen Stimulates Delayed Mitogen-Activated Protein Kinase Activity in Human Endothelial Cells via an Autocrine Loop That Involves Basic Fibroblast Growth Factor

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

The Steroid and Thyroid Hormone Receptor Superfamily

1988 • 7,590 citations

Cloning of a novel receptor expressed in rat prostate and ovary.

1996 • 4,782 citations

ERβ: Identification and characterization of a novel human estrogen receptor

1996 • 2,262 citations

Activation of the Estrogen Receptor Through Phosphorylation by Mitogen-Activated Protein Kinase

1995 • 1,973 citations

How MAP Kinases Are Regulated

1995 • 1,742 citations

Phenol red in tissue culture media is a weak estrogen: implications concerning the study of estrogen-responsive cells in culture.

1986 • 1,282 citations

Menopause and the Risk of Coronary Heart Disease in Women

1987 • 1,137 citations

Nucleotide Sequence of a Bovine Clone Encoding the Angiogenic Protein, Basic Fibroblast Growth Factor

1986 • 1,032 citations

Mitogen-activated protein kinases p42mapk and p44mapk are required for fibroblast proliferation.

1993 • 992 citations

Tyrosine kinase/p21ras/MAP-kinase pathway activation by estradiol-receptor complex in MCF-7 cells.

1996 • 964 citations

Cloning, Chromosomal Localization, and Functional Analysis of the Murine Estrogen Receptor β

1997 • 862 citations

Steroid Receptor Family: Structure and Functions

1990 • 820 citations

Estrogen action via the cAMP signaling pathway: stimulation of adenylate cyclase and cAMP-regulated gene transcription.

1994 • 667 citations

Inhibition of coronary artery atherosclerosis by 17-beta estradiol in ovariectomized monkeys. Lack of an effect of added progesterone.

1990 • 603 citations

Estrogenic Regulation of Growth and Polypeptide Growth Factor Secretion in Human Breast Carcinoma

1987 • 576 citations

Acute vascular effects of estrogen in postmenopausal women.

1994 • 557 citations

Human vascular smooth muscle cells contain functional estrogen receptor.

1994 • 501 citations

Variable expression of the estrogen receptor in normal and atherosclerotic coronary arteries of premenopausal women.

1994 • 499 citations

Estrogen Promotes Angiogenic Activity in Human Umbilical Vein Endothelial Cells In Vitro and in a Murine Model

1995 • 458 citations

Identification of Six Novel Autophosphorylation Sites on Fibroblast Growth Factor Receptor 1 and Elucidation of Their Importance in Receptor Activation and Signal Transduction

1996 • 385 citations

Identification of Authentic Estrogen Receptor in Cultured Endothelial Cells

1996 • 331 citations

Human Estrogen Receptor β Binds DNA in a Manner Similar to and Dimerizes with Estrogen Receptor α

1997 • 301 citations

Type IV collagenase(s) and TIMPs modulate endothelial cell morphogenesis in vitro

1993 • 296 citations

Fluid Shear Stress Stimulates Mitogen-Activated Protein Kinase in Endothelial Cells

1995 • 287 citations

Influence of Estrogens on Mouse Uterine Epidermal Growth Factor Precursor Protein and Messenger Ribonucleic Acid

1988 • 273 citations

Transcriptional activation by the estrogen receptor requires a conformational change in the ligand binding domain.

1993 • 249 citations

Estradiol enhances leukocyte binding to tumor necrosis factor (TNF)-stimulated endothelial cells via an increase in TNF-induced adhesion molecules E-selectin, intercellular adhesion molecule type 1, and vascular cell adhesion molecule type 1.

1994 • 235 citations

Activation of mitogen-activated protein kinases by vascular endothelial growth factor and basic fibroblast growth factor in capillary endothelial cells is inhibited by the antiangiogenic factor 16-kDa N-terminal fragment of prolactin.

1995 • 231 citations

Expression of an Estrogen Receptor by Human Coronary Artery and Umbilical Vein Endothelial Cells

1996 • 218 citations

Stimulation by growth hormone of MAP kinase activity in 3T3-F442A fibroblasts.

1992 • 164 citations

Release of basic fibroblast growth factor, an angiogenic factor devoid of secretory signal sequence: A trivial phenomenon or a novel secretion mechanism?

1991 • 140 citations

Regulation of gene expression by nuclear hormone receptors

1989 • 133 citations

Disruption of estrogen receptor gene prevents 17 beta estradiol-induced angiogenesis in transgenic mice.

1996 • 124 citations

p42/mitogen-activated protein kinase as a converging target for different growth factor signaling pathways: use of pertussis toxin as a discrimination factor.

1991 • 121 citations

Angiogenic role of endogenous basic fibroblast growth factor released by rat aorta after injury.

1993 • 120 citations

Shear Stress Activates Cytosolic Phospholipase A2(cPLA2) and MAP Kinase in Human Endothelial Cells

1996 • 118 citations

Point mutation in the fibroblast growth factor receptor eliminates phosphatidylinositol hydrolysis without affecting neuronal differentiation of PC12 cells.

1994 • 88 citations

Regulation of uterine epidermal growth factor (EGF) receptors by estrogen in the mature rat and during the estrous cycle

1989 • 86 citations

Biphasic Effect of Estrogen on Neuronal Constitutive Nitric Oxide Synthase via Ca2+-Calmodulin Dependent Mechanism

1994 • 81 citations

Differential activation of mitogen-activated protein kinase in response to basic fibroblast growth factor in skeletal muscle cells.

1995 • 76 citations

The clinical aspects of estrogen and the cardiovascular system

1996 • 76 citations

The 27-kDa Heat Shock Protein Facilitates Basic Fibroblast Growth Factor Release from Endothelial Cells

1997 • 65 citations

Identification of a specific pattern of "immediate-early" gene activation induced by estrogen during mitogenic stimulation of rat uterine cells.

1993 • 58 citations

Senescence of aortic endothelial cells in culture: Effects of basic fibroblast growth factor expression on cell phenotype, migration, and proliferation

1993 • 57 citations

Growth factors interact with estradiol and gonadotropins in the regulation of ovarian cancer cell growth and growth factor receptors.

1993 • 51 citations

Effects of Estrogen Treatment on Arterial Wall Structure and Function

1994 • 45 citations

II. Stromal and Epithelial Cells from Rat Ventral Prostate during Androgen Deprivation and Estrogen Treatment — Regulation of Transcription

2009 • 43 citations

Tumor cells secrete an Angiogenic factor that stimulates basic fibroblast growth factor and Urokinase expression in Vascular Endothelial cells

1994 • 37 citations

Differential regulation of acidic and basic fibroblast growth factor gene expression in fibroblast growth factor-treated rat aortic smooth muscle cells.

1994 • 31 citations

Localization of bFGF mRNA in Cyclic Rat Ovary, Diethylstilbesterol Primed Rat Ovary, and Cultured Rat Granulosa Cells

1992 • 28 citations

Protein Tyrosine Phosphorylation and Estradiol Action^a

1996 • 25 citations