Conformational Plasticity Revealed by the Cocrystal Structure of NKG2D and Its Class I MHC-like Ligand ULBP3

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The CCP4 suite: programs for protein crystallography

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Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

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MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

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Protein folding and association: Insights from the interfacial and thermodynamic properties of hydrocarbons

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AMoRe: an automated package for molecular replacement

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In search of the ‘missing self’: MHC molecules and NK cell recognition

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Human Growth Hormone and Extracellular Domain of Its Receptor: Crystal Structure of the Complex

1992 • 2,236 citations

Activating Receptors and Coreceptors Involved in Human Natural Killer Cell-Mediated Cytolysis

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NK CELL RECEPTORS

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An αβ T Cell Receptor Structure at 2.5 Å and Its Orientation in the TCR-MHC Complex

1996 • 1,282 citations

Shape complementarity at protein–protein interfaces

1994 • 1,217 citations

Atomic Structures of the Human Immunophilin FKBP-12 Complexes with FK506 and Rapamycin

1993 • 1,202 citations

ULBPs, Novel MHC Class I–Related Molecules, Bind to CMV Glycoprotein UL16 and Stimulate NK Cytotoxicity through the NKG2D Receptor

2001 • 1,190 citations

REGULATION OF IMMUNE RESPONSES THROUGH INHIBITORY RECEPTORS

1999 • 947 citations

Costimulation of CD8αβ T cells by NKG2D via engagement by MIC induced on virus-infected cells

2001 • 937 citations

Ligands for the murine NKG2D receptor: expression by tumor cells and activation of NK cells and macrophages

2000 • 864 citations

Retinoic Acid Early Inducible Genes Define a Ligand Family for the Activating NKG2D Receptor in Mice

2000 • 694 citations

Structural Basis of Plasticity in T Cell Receptor Recognition of a Self Peptide-MHC Antigen

1998 • 685 citations

Functional Mimicry of a Protein Hormone by a Peptide Agonist: The EPO Receptor Complex at 2.8 Å

1996 • 589 citations

Mouse CD94/NKG2A Is a Natural Killer Cell Receptor for the Nonclassical Major Histocompatibility Complex (MHC) Class I Molecule Qa-1b

1998 • 491 citations

Two Human T Cell Receptors Bind in a Similar Diagonal Mode to the HLA-A2/Tax Peptide Complex Using Different TCR Amino Acids

1998 • 438 citations

The Crystal Structure of a T Cell Receptor in Complex with Peptide and MHC Class II

1999 • 400 citations

Crystal structure of an NK cell immunoglobulin-like receptor in complex with its class I MHC ligand

2000 • 399 citations

MICA Engagement by Human Vγ2Vδ2 T Cells Enhances Their Antigen-Dependent Effector Function

2001 • 394 citations

Complex structure of the activating immunoreceptor NKG2D and its MHC class I–like ligand MICA

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The Inhibitory Receptor LIR-1 Uses a Common Binding Interaction to Recognize Class I MHC Molecules and the Viral Homolog UL18

1999 • 357 citations

The Structure of a Human Type III Fcγ Receptor in Complex with Fc

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Crystal structure of the hereditary haemochromatosis protein HFE complexed with transferrin receptor

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Structure of the Fc fragment of human IgE bound to its high-affinity receptor FcεRIα

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Crystal structure at 2.2 Å resolution of the MHC-related neonatal Fc receptor

1994 • 320 citations

Natural killer cell receptors

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Crystal structure of the human natural killer cell inhibitory receptor KIR2DL1–HLA-Cw4 complex

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Crystal structure of a lectin-like natural killer cell receptor bound to its MHC class I ligand

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Structure of a Heterophilic Adhesion Complex between the Human CD2 and CD58 (LFA-3) Counterreceptors

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Structural Features Impose Tight Peptide Binding Specificity in the Nonclassical MHC Molecule HLA-E

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Structural Plasticity in a Remodeled Protein-Protein Interface

1997 • 181 citations

Crystal Structure of the MHC Class I Homolog MIC-A, a γδ T Cell Ligand

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Efficient Rebuilding of Protein Structures

1996 • 148 citations

Natural killer cell receptors

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Peptide sequence requirements for the recognition of HLA-B*2705 by specific natural killer cells.

1996 • 142 citations

Structure of CD94 Reveals a Novel C-Type Lectin Fold

1999 • 127 citations

Killer Cell Immunoglobulin Receptors and T Cell Receptors Bind Peptide-Major Histocompatibility Complex Class I with Distinct Thermodynamic and Kinetic Properties

1999 • 122 citations

Crystal structure of the HLA-Cw3 allotype-specific killer cell inhibitory receptor KIR2DL2

1999 • 110 citations

Peptides isolated from HLA-Cw*0304 confer different degrees of protection from natural killer cell-mediated lysis

1997 • 107 citations

Crystal structure of the murine NK cell–activating receptor NKG2D at 1.95 Å

2001 • 87 citations

Imperfect interfaces

1998 • 32 citations

Reconstitution of Bacterial Expressed Human CD94: The Importance of the Stem Region for Dimer Formation

2000 • 11 citations