A fraction of the mRNA 5' cap-binding protein, eukaryotic initiation factor 4E, localizes to the nucleus.

Nuclear targeting sequences — a consensus?

1991 • 1,908 citations

Capping of eucaryotic mRNAs

1976 • 1,141 citations

Purification of a RAS-responsive adenylyl cyclase complex from Saccharomyces cerevisiae by use of an epitope addition method.

1988 • 983 citations

Malignant transformation by a eukaryotic initiation factor subunit that binds to mRNA 5' cap

1990 • 949 citations

Monoclonal antibodies to nucleic acid-containing cellular constituents: probes for molecular biology and autoimmune disease.

1981 • 725 citations

Factor required for mammalian spliceosome assembly is localized to discrete regions in the nucleus

1990 • 723 citations

Mutational analysis of a DEAD box RNA helicase: the mammalian translation initiation factor eIF-4A.

1992 • 613 citations

Recognition of cap structure in splicing in vitro of mRNA precursors

1984 • 575 citations

Nuclear transport of influenza virus ribonucleoproteins: The viral matrix protein (M1) promotes export and inhibits import

1991 • 559 citations

5′-Terminal structure and mRNA stability

1977 • 542 citations

Regulated phosphorylation and low abundance of HeLa cell initiation factor eIF-4F suggest a role in translational control. Heat shock effects on eIF-4F.

1987 • 494 citations

Expression of the Wilms' tumor gene WT1 in the murine urogenital system.

1991 • 447 citations

New initiation factor activity required for globin mRNA translation.

1983 • 416 citations

Monomethylated cap structures facilitate RNA export from the nucleus

1990 • 411 citations

A polypeptide in eukaryotic initiation factors that crosslinks specifically to the 5'-terminal cap in mRNA.

1978 • 365 citations

Purification of a RAS-Responsive Adenylyl Cyclase Complex from Saccharomyces cerevisiae by Use of an Epitope Addition Method

1988 • 328 citations

Cap-Binding Proteins of Eukaryotic Messenger RNA: Functions in Initiation and Control of Translation

1988 • 266 citations

Eukaryotic mRNA cap binding protein: purification by affinity chromatography on sepharose-coupled m7GDP.

1979 • 259 citations

Cap recognition and the entry of mRNA into the protein synthesis initiation cycle

1988 • 256 citations

Mammalian nuclei contain foci which are highly enriched in components of the pre-mRNA splicing machinery.

1991 • 243 citations

Involvement of eukaryotic initiation factor 4A in the cap recognition process.

1983 • 236 citations

Two forms of purified m7G-cap binding protein with different effects on capped mRNA translation in extracts of uninfected and poliovirus-infected HeLa cells.

1981 • 224 citations

Immunological detection of the messenger RNA cap-binding protein.

1985 • 201 citations

The mRNA 5' cap-binding protein, eIF-4E, cooperates with v-myc or E1A in the transformation of primary rodent fibroblasts.

1992 • 172 citations

Cap-dependent RNA splicing in a HeLa nuclear extract.

1985 • 156 citations

Poly(A) site cleavage in a HeLa nuclear extract is dependent on downstream sequences

1985 • 152 citations

Role of mRNA competition in regulating translation: further characterization of mRNA discriminatory initiation factors.

1983 • 152 citations

Nuclear localization of Semliki Forest virus-specific nonstructural protein nsP2

1990 • 134 citations

Differential stimulation of capped mRNA translation in vitro by cap binding protein

1980 • 107 citations

High-level synthesis in Escherichia coli of functional cap-binding eukaryotic initiation factor eIF-4E and affinity purification using a simplified cap-analog resin

1988 • 92 citations

RNA Polymerase II Subunit RPB3 Is an Essential Component of the mRNA Transcription Apparatus

1989 • 91 citations

Spliceosomes and Snurposomes

1991 • 85 citations

Purification and characterization of protein synthesis initiation factor eIF-4E from the yeast Saccharomyces cerevisiae

1985 • 85 citations

Isolation and characterization of factors from wheat germ that exhibit eukaryotic initiation factor 4B activity and overcome 7-methylguanosine 5'-triphosphate inhibition of polypeptide synthesis.

1985 • 82 citations

Processing and nucleo-cytoplasmic transport of histone gene transcripts

1984 • 79 citations

A nuclear cap binding protein from HeLa cells

1990 • 78 citations

Identification and characterization of cap-binding proteins from yeast

1989 • 62 citations

Preferential stimulation of rabbit α globin mRNA translation by a cap-binding protein complex

1984 • 57 citations

CAP binding proteins associated with the nucleus

1983 • 54 citations

Increased proportion of B cell hybridomas secreting monoclonal antibodies of desired specificity in cultures containing macrophage-derived hybridoma growth factor (IL-6)

1989 • 51 citations

The mRNA 5' Cap-Binding Protein, eIF-4E, Cooperates with v-myc or E1A in the Transformation of Primary Rodent Fibroblasts

1992 • 47 citations

Identification of nuclear cap specific proteins in HeLa cells

1987 • 45 citations

Early capping of transcripts from the adenovirus major late transcription unit

1980 • 42 citations

Monoclonal antibody-aided characterization of cellular p220 in uninfected and poliovirus-infected HeLa cells: subcellular distribution and identification of conformers

1987 • 39 citations

Purification and characterization of mRNA cap-binding protein from Drosophila melanogaster embryos.

1989 • 32 citations

A wheat germ cap-site factor functional in protein chain initiation

1986 • 30 citations

Localization of Cap-Binding Protein in Subcellular Fractions of HeLa Cells

1982 • 19 citations

Localization of Cap-Binding Protein in Subcellular Fractions of HeLa Cells

1982 • 8 citations

Purification and Characterization of mRNA Cap-Binding Protein from Drosophila melanogaster Embryos

1989 • 7 citations