Spliceosomes and Snurposomes

Antibodies to small nuclear RNAs complexed with proteins are produced by patients with systemic lupus erythematosus

1979 • 1,178 citations

Factor required for mammalian spliceosome assembly is localized to discrete regions in the nucleus

1990 • 723 citations

The role of small nuclear ribonucleoprotein particles in pre-mRNA splicing

1987 • 594 citations

Splice site selection, rate of splicing, and alternative splicing on nascent transcripts.

1988 • 539 citations

The "Spliceosome": Yeast Pre-Messenger RNA Associates with a 40 S Complex in a Splicing-Dependent Reaction

1985 • 421 citations

Structure and Function of Major and Minor Small Nuclear Ribonucleoprotein Particles

1988 • 363 citations

Biochemical characterization of U2 snRNP auxiliary factor: an essential pre-mRNA splicing factor with a novel intranuclear distribution.

1991 • 255 citations

Mammalian nuclei contain foci which are highly enriched in components of the pre-mRNA splicing machinery.

1991 • 243 citations

Structure and Function of Nuclear and Cytoplasmic Ribonucleoprotein Particles

1986 • 243 citations

Higher order nuclear organization: three-dimensional distribution of small nuclear ribonucleoprotein particles.

1990 • 225 citations

RNP particles at splice junction sequences on Drosophila chorion transcripts

1985 • 191 citations

Small nuclear ribonucleoproteins and heterogeneous nuclear ribonucleoproteins in the amphibian germinal vesicle: loops, spheres, and snurposomes.

1991 • 182 citations

Nucleocytoplasmic distribution of snRNPs and stockpiled snRNA-binding proteins during oogenesis and early development in Xenopus laevis

1983 • 182 citations

Cell Biology of the snRNP Particle

1990 • 163 citations

Intranuclear localization of snRNP antigens.

1986 • 140 citations

Purification and visualization of native spliceosomes

1988 • 121 citations

Protein composition of mammalian spliceosomes assembled in vitro.

1990 • 112 citations

Redistribution of U-snRNPs during mitosis

1986 • 108 citations

Small nuclear RNA transcription and ribonucleoprotein assembly in early Xenopus development.

1983 • 96 citations

The sphere organelle contains small nuclear ribonucleoproteins.

1989 • 86 citations

Transcription-dependent localization of U1 and U2 small nuclear ribonucleoproteins at major sites of gene activity in polytene chromosomes

1984 • 77 citations

Immunoelectron microscope localization of snRNPs in the polytene nucleus of salivary glands ofChironomus thummi

1990 • 43 citations