The mRNA 5' cap-binding protein, eIF-4E, cooperates with v-myc or E1A in the transformation of primary rodent fibroblasts.

Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes

1983 • 2,871 citations

Adenovirus early region 1A enables viral and cellular transforming genes to transform primary cells in culture

1983 • 1,358 citations

DNA-mediated transfer of the adenine phosphoribosyltransferase locus into mammalian cells.

1979 • 1,339 citations

Oncogenes, antioncogenes, and the molecular bases of multistep carcinogenesis.

1989 • 961 citations

Malignant transformation by a eukaryotic initiation factor subunit that binds to mRNA 5' cap

1990 • 949 citations

Cooperation between oncogenes

1991 • 792 citations

Isolation of a transforming sequence from a human bladder carcinoma cell line

1982 • 776 citations

The Action of Oncogenes in the Cytoplasm and Nucleus

1985 • 708 citations

Bidirectional RNA helicase activity of eucaryotic translation initiation factors 4A and 4F.

1990 • 632 citations

Regulated phosphorylation and low abundance of HeLa cell initiation factor eIF-4F suggest a role in translational control. Heat shock effects on eIF-4F.

1987 • 494 citations

Malignant transformation of early passage rodent cells by a single mutated human oncogene

1984 • 479 citations

Human papillomavirus type 16 DNA cooperates with activated ras in transforming primary cells.

1987 • 351 citations

Protein Phosphorylation Controls Translation Rates

1989 • 303 citations

Overexpression of eukaryotic protein synthesis initiation factor 4E in HeLa cells results in aberrant growth and morphology.

1990 • 281 citations

Behavior of myc and ras oncogenes in transformation of rat embryo fibroblasts.

1986 • 272 citations

The Regulation of Initiation of Mammalian Protein Synthesis

1981 • 266 citations

Cap-Binding Proteins of Eukaryotic Messenger RNA: Functions in Initiation and Control of Translation

1988 • 266 citations

Cap recognition and the entry of mRNA into the protein synthesis initiation cycle

1988 • 256 citations

Expression of the large T protein of polyoma virus promotes the establishment in culture of "normal" rodent fibroblast cell lines.

1983 • 240 citations

Involvement of the 24-kDa cap-binding protein in regulation of protein synthesis in mitosis.

1987 • 220 citations

Translational activation of the lck proto-oncogene

1988 • 203 citations

Immunological detection of the messenger RNA cap-binding protein.

1985 • 201 citations

Differential stimulation of phosphorylation of initiation factors eIF-4F, eIF-4B, eIF-3, and ribosomal protein S6 by insulin and phorbol esters.

1990 • 197 citations

The 5′ Untranslated Sequence of the c-sis/Platelet-Derived Growth Factor 2 Transcript Is a Potent Translational Inhibitor

1988 • 180 citations

Adenovirus inhibition of cellular protein synthesis involves inactivation of cap-binding protein

1991 • 177 citations

Construction and Characterization of a Retroviral Vector Demonstrating Efficient Expression of Cloned cDNA Sequences

1988 • 157 citations

Regulation of rat ornithine decarboxylase mRNA translation by its 5'-untranslated region.

1990 • 154 citations

Alteration of the major phosphorylation site of eukaryotic protein synthesis initiation factor 4E prevents its association with the 48 S initiation complex.

1990 • 133 citations

Augmented expression of normal c-myc is sufficient for cotransformation of rat embryo cells with a mutant ras gene.

1985 • 117 citations

The zinc finger protein GLI transforms primary cells in cooperation with adenovirus E1A.

1991 • 107 citations

Differential efficiencies of in vitro translation of mouse c-myc transcripts differing in the 5' untranslated region.

1985 • 104 citations

Phosphorylation of eukaryotic translation initiation factor 4E is increased in Src-transformed cell lines.

1991 • 95 citations

Phosphorylation site of eukaryotic initiation factor 4E.

1987 • 95 citations

The 5' untranslated sequence of the c-sis/platelet-derived growth factor 2 transcript is a potent translational inhibitor.

1988 • 94 citations

Phosphorylation of eIF-4F by protein kinase C or multipotential S6 kinase stimulates protein synthesis at initiation.

1991 • 83 citations

Translation initiation factors induce DNA synthesis and transform NIH 3T3 cells.

1990 • 79 citations

Sequences from polyomavirus and simian virus 40 large T genes capable of immortalizing primary rat embryo fibroblasts

1985 • 74 citations

Translational control of ornithine aminotransferase. Modulation by initiation factor eIF-4E.

1991 • 66 citations

Complementation by BCL2 and C-HA-RAS Oncogenes in Malignant Transformation of Rat Embryo Fibroblasts

1990 • 42 citations

Phosphorylation of the proto-oncogene product eukaryotic initiation factor 4E is a common cellular response to tumor necrosis factor.

1991 • 35 citations

Complementation by BCL2 and C-HA-RAS oncogenes in malignant transformation of rat embryo fibroblasts.

1990 • 31 citations

Phosphorylation of Eukaryotic Translation Initiation Factor 4E Is Increased in Src-Transformed Cell Lines

1991 • 22 citations

Initiation of mammalian protein biosynthesis

1976 • 11 citations

Deleted Work

1955 • 0 citations