Mutator phenotype of BCR – ABL transfected Ba/F3 cell lines and its association with enhanced expression of DNA polymerase β

A New Consistent Chromosomal Abnormality in Chronic Myelogenous Leukaemia identified by Quinacrine Fluorescence and Giemsa Staining

1973 • 4,217 citations

Mutations of mitotic checkpoint genes in human cancers

1998 • 1,482 citations

Structural organization of the bcr gene and its role in the Ph′ translocation

1985 • 920 citations

Chronic myelocytic leukemia: Clonal origin in a stem cell common to the granulocyte, erythrocyte, platelet and monocyte/macrophage

1977 • 888 citations

Requirement of mammalian DNA polymerase-β in base-excision repair

1996 • 820 citations

Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination, and predisposition to cancer

1995 • 785 citations

The mutational specificity of DNA polymerase-beta during in vitro DNA synthesis. Production of frameshift, base substitution, and deletion mutations.

1985 • 317 citations

Alterations in the p53 gene and the clonal evolution of the blast crisis of chronic myelocytic leukemia.

1989 • 300 citations

Genetic requirement for Ras in the transformation of fibroblasts and hematopoietic cells by the Bcr-Abl oncogene.

1995 • 268 citations

p53 in chronic myelogenous leukemia in acute phase.

1991 • 224 citations

Overexpression of DNA polymerase β in cell results in a mutator phenotype and a decreased sensitivity to anticancer drugs

1998 • 189 citations

The spectrum of molecular alterations in the evolution of chronic myelocytic leukemia.

1991 • 171 citations

Induction of beta-polymerase mRNA by DNA-damaging agents in Chinese hamster ovary cells.

1989 • 158 citations

Rearrangements in the p53 gene in Philadelphia chromosome positive chronic myelogenous leukemia [see comments]

1989 • 157 citations

Role of p21 RAS in p210 bcr-abl transformation of murine myeloid cells

1993 • 150 citations

Rearrangement and expression of p53 in the chronic phase and blast crisis of chronic myelogenous leukemia

1990 • 138 citations

Genomic instability of microsatellite repeats and its association with the evolution of chronic myelogenous leukemia [see comments]

1994 • 137 citations

Rearrangement and expression of p53 in the chronic phase and blast crisis of chronic myelogenous leukemia

1990 • 108 citations

Human DNA polymerases alpha and beta are able to incorporate anti-HIV deoxynucleotides into DNA.

1992 • 105 citations

GENOMIC ALTERATIONS INVOLVING THE C-MYC PROTO-ONCOGENE LOCUS DURING THE EVOLUTION OF A CASE OF CHRONIC GRANULOCYTIC LEUKAEMIA

1984 • 91 citations

Characterization of DNA polymerase β mRNA: cell-cycle and growth response in cultured human cells

1988 • 81 citations

Clonal evolution in a myeloid cell line transformed to interleukin-3 independent growth by retroviral transduction and expression of p210bcr/abl

1992 • 78 citations

Differential Gene Expression in Human Cancer Cells Resistant to Cisplatin

1989 • 53 citations

Fork-like DNA templates support bypass replication of lesions that block DNA synthesis on single-stranded templates

1996 • 46 citations

Transfected human beta-polymerase promoter contains a ras-responsive element.

1990 • 34 citations

Overexpression of DNA polymerase beta sensitizes mammalian cells to 2',3'-deoxycytidine and 3'-azido-3'-deoxythymidine.

1997 • 33 citations

BCR-ABL and constitutively active erythropoietin receptor (cEpoR) activate distinct mechanisms for growth factor-independence and inhibition of apoptosis in Ba/F3 cell line

1998 • 23 citations

Regular Structures

1991 • 16 citations

Clonal evolution in a myeloid cell line transformed to interleukin-3 independent growth by retroviral transduction and expression of p210bcr/abl

1992 • 7 citations

Ras oncogene mutations are rare late stage events in chronic myelogenous leukemia

1989 • 5 citations

Rare occurrence of N-ras point mutations in Philadelphia chromosome positive chronic myeloid leukemia

1989 • 3 citations

Joshua Smith: The Once and Future Chancellor

1988 • 1 citations