Inhibition of Rat Cardiac Muscle Contraction and Mitochondrial Respiration by Endogenous Peroxynitrite Formation During Posthypoxic Reoxygenation

Mechanism of vascular smooth muscle relaxation by organic nitrates, nitrites, nitroprusside and nitric oxide: evidence for the involvement of S-nitrosothiols as active intermediates.

1981 • 1,624 citations

Reversible inhibition of cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, by nitric oxide

1994 • 1,214 citations

Nanomolar concentrations of nitric oxide reversibly inhibit synaptosomal respiration by competing with oxygen at cytochrome oxidase

1994 • 1,026 citations

Regional myocardial functional and electrophysiological alterations after brief coronary artery occlusion in conscious dogs.

1975 • 1,004 citations

Nitric Oxide and Cardiac Function

1996 • 721 citations

Inhibition of Mitochondrial Electron Transport by Peroxynitrite

1994 • 697 citations

Stretch-induced programmed myocyte cell death.

1995 • 647 citations

Measurement of Nitric Oxide and Peroxynitrite Generation in the Postischemic Heart

1996 • 543 citations

Redox modulation of L-type calcium channels in ferret ventricular myocytes. Dual mechanism regulation by nitric oxide and S-nitrosothiols.

1996 • 444 citations

Nitric oxide attenuates cardiac myocyte contraction

1993 • 405 citations

The effects of inorganic phosphate and creatine phosphate on force production in skinned muscles from rat ventricle.

1986 • 343 citations

Generation of peroxynitrite contributes to ischemia-reperfusion injury in isolated rat hearts

1997 • 339 citations

Nitric Oxide Potently and Reversibly Deenergizes Mitochondria at Low Oxygen Tension

1994 • 324 citations

Role of nitric oxide in the regulation of oxygen consumption in conscious dogs.

1994 • 320 citations

Role of L-arginine-nitric oxide pathway in myocardial reoxygenation injury

1992 • 312 citations

Nitric Oxide

1995 • 266 citations

Rapid reduction of nitric oxide by mitochondria, and reversible inhibition of mitochondrial respiration by nitric oxide

1996 • 243 citations

Factors released from endocardium of the ferret and pig modulate myocardial contraction.

1991 • 242 citations

Role of Endothelium-Derived Nitric Oxide in the Modulation of Canine Myocardial Mitochondrial Respiration In Vitro

1996 • 233 citations

Lucigenin (Bis-N-methylacridinium) as a Mediator of Superoxide Anion Production

1997 • 220 citations

Mechanism of covalent modification of glyceraldehyde‐3‐phosphate dehydrogenase at its active site thiol by nitric oxide, peroxynitrite and related nitrosating agents

1994 • 212 citations

Nitric oxide inhibits creatine kinase and regulates rat heart contractile reserve.

1996 • 204 citations

Function and Production of Nitric Oxide in the Coronary Circulation of the Conscious Dog During Exercise

1996 • 190 citations

The Oxidative Inactivation of Sarcoplasmic Reticulum Ca²⁺-ATPase by Peroxynitrite

1996 • 162 citations

Role of Nitric Oxide and Its Interaction With Superoxide in the Suppression of Cardiac Muscle Mitochondrial Respiration

1996 • 153 citations

On the Mechanism of Inhibition of Cytochrome c Oxidase by Nitric Oxide

1996 • 142 citations

Global ischaemia induces a biphasic response of the mitochondrial respiratory chain. Anoxic pre-perfusion protects against ischaemic damage

1992 • 141 citations

Reoxygenation-dependent decrease in mitochondrial NADH:CoQ reductase (Complex I) activity in the hypoxic/reoxygenated rat heart

1991 • 126 citations

Development of ischemia-induced damage in defined mitochondrial subpopulations

1985 • 109 citations

Peroxynitrite impairs cardiac contractile function by decreasing cardiac efficiency

1997 • 103 citations

Evidence Against the Involvement of Cytochrome P450 Metabolites in Endothelium‐Dependent Hyperpolarization of the Rat Main Mesenteric Artery

1997 • 102 citations

The consequences of simulated ischaemia on intracellular Ca2+ and tension in isolated ferret ventricular muscle.

1989 • 100 citations

Metabolic changes during ischaemia and their role in contractile failure in isolated ferret hearts.

1992 • 86 citations

Endothelial‐derived superoxide anions in pig coronary arteries: evidence from lucigenin chemiluminescence and histochemical techniques.

1997 • 80 citations

Cytochrome c Oxidase Catalysis of the Reduction of Nitric Oxide to Nitrous Oxide

1995 • 72 citations

Creatine kinase of heart mitochondria. The progressive loss of enzyme activity during in vivo ischemia and its correlation to depressed myocardial function.

1985 • 64 citations

Direct measurement of the accumulation and mitochondrial conversion of nitric oxide within Chinese hamster ovary cells using an intracellular electron paramagnetic resonance technique

1995 • 54 citations

Inhibition of glyceraldehyde-3-phosphate dehydrogenase in post-ischaemic myocardium

1996 • 51 citations

NO elicits prolonged relaxation of bovine pulmonary arteries via endogenous peroxynitrite generation

1997 • 50 citations

Involvement of reactive oxygen and nitrogen species in signalling mechanisms that control tissue respiration in muscle

1997 • 45 citations

The contribution of intracellular acidosis to the decline of developed pressure in ferret hearts exposed to cyanide.

1987 • 40 citations

Mitochondrial Response to Heart Rate Steps in Isolated Rabbit Heart Is Slowed After Myocardial Stunning

1997 • 31 citations

Cardioprotective Effects of Recombinant Human Extracellular-Superoxide Dismutase Type C in Rat Isolated Heart Subjected to Ischemia and Reperfusion

1991 • 29 citations

Differences in load dependence of relaxation between the left and right ventricular myocardium as a function of age in rats.

1989 • 22 citations

Hypoxia Increases Superoxide Anion Production from Bovine Coronary Microvessels, But Not Cardiac Myocytes, via Increased Xanthine Oxidase

1994 • 21 citations

Nonsuperoxide lucigenin-enhanced chemiluminescence from phospholipids and human saphenous veins

1995 • 13 citations

Effects of Hypoxia and Reoxygenation on Regular Contractions and Postrest Contraction in Rat Papillary Musles.

1991 • 6 citations

A Molecular Switch in Cytochrome C Oxidase Turns on Thermogenesis in Heart at Low Work Load

1996 • 4 citations

Involvement of reactive O2 and N2 species in signalling mechanisms that control tissue respiration in muscle

1997 • 3 citations

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