The generation of memory antigen‐specific cytotoxic T cell responses by CD28/CD80 interactions in the absence of antigen

MHC-Restricted Cytotoxic T Cells: Studies on the Biological Role of Polymorphic Major Transplantation Antigens Determining T-Cell Restriction-Specificity, Function, and Responsiveness

1979 • 1,969 citations

The B7 and CD28 receptor families

1994 • 1,342 citations

Establishment of mouse cell lines which constitutively secrete large quantities of interleukin 2, 3, 4 or 5, using modified cDNA expression vectors

1988 • 1,086 citations

Induction of Bystander T Cell Proliferation by Viruses and Type I Interferon in Vivo

1996 • 1,077 citations

Turnover of naive- and memory-phenotype T cells.

1994 • 900 citations

Naive and memory T cells show distinct pathways of lymphocyte recirculation.

1990 • 792 citations

Cytotoxic T-cell memory without antigen

1994 • 669 citations

Lifespan of human lymphocyte subsets defined by CD45 isoforms

1992 • 642 citations

Antigen-independent activation of naive and memory resting T cells by a cytokine combination.

1994 • 541 citations

Virus-specific CD8+ T-cell memory determined by clonal burst size

1994 • 525 citations

Long-term acceptance of major histocompatibility complex mismatched cardiac allografts induced by CTLA4Ig plus donor-specific transfusion.

1993 • 502 citations

Naive versus memory CD4 T cell response to antigen. Memory cells are less dependent on accessory cell costimulation and can respond to many antigen-presenting cell types including resting B cells.

1994 • 498 citations

Lymphocyte life-span and memory

1994 • 405 citations

T cell memory is short-lived in the absence of antigen.

1991 • 367 citations

CD28 interaction with B7 costimulates primary allogeneic proliferative responses and cytotoxicity mediated by small, resting T lymphocytes.

1992 • 342 citations

Cross-reactivities in memory cytotoxic T lymphocyte recognition of heterologous viruses.

1994 • 317 citations

Generation and in vivo persistence of polarized Th1 and Th2 memory cells

1994 • 283 citations

In vivo estimates of division and death rates of human T lymphocytes.

1995 • 276 citations

CD28-B7 interactions allow the induction of CD8+ cytotoxic T lymphocytes in the absence of exogenous help.

1993 • 274 citations

Is T-cell memory maintained by crossreactive stimulation?

1990 • 253 citations

Reduction of otherwise remarkably stable virus-specific cytotoxic T lymphocyte memory by heterologous viral infections.

1996 • 219 citations

Antivirally protective cytotoxic T cell memory to lymphocytic choriomeningitis virus is governed by persisting antigen.

1992 • 204 citations

The long-term maintenance of cytotoxic T cell memory does not require persistence of antigen.

1994 • 190 citations

On the cellular basis of immunological T cell memory

1995 • 159 citations

Interleukin 2 is both necessary and sufficient for the growth and differentiation of lectin-stimulated cytolytic T lymphocyte precursors.

1985 • 141 citations

Enhanced recognition of a modified peptide antigen by cytotoxic T cells specific for influenza nucleoprotein

1988 • 140 citations

Concurrent production of interleukin-2, interleukin-10, and gamma interferon in the regional lymph nodes of mice with influenza pneumonia

1994 • 134 citations

Recruitment and proliferation of CD8+ T cells in respiratory virus infections.

1995 • 130 citations

Temporal loss of the activated L-selectin-low phenotype for virus-specific CD8+ memory T cells.

1995 • 130 citations

B7-1 but not B7-2 efficiently costimulates CD8+ T lymphocytes in the P815 tumor system in vitro.

1996 • 123 citations

Selectively increased production of interferon-gamma by subsets of Lyt-2+ and L3T4+ T cells identified by expression of Pgp-1.

1987 • 120 citations

Cytolytic T Lymphocytes

1983 • 119 citations

Cytotoxic T cells specific for influenza virus-infected target cells.

1977 • 114 citations

The Cellular Basis of Immunologic Memory

1971 • 111 citations

Cell‐mediated cytotoxicity against ectromelia virus‐infected target cells. I. Specificity and kinetics

1974 • 110 citations

Ly-6C is a marker of memory CD8+ T cells.

1995 • 109 citations

CD8+ T-cell memory to viruses

1994 • 96 citations

In vivo state of antiviral CTL precursors. Characterization of a cycling cell population containing CTL precursors in immune mice.

1995 • 81 citations

Simultaneous ligation of CD5 and CD28 on resting T lymphocytes induces T cell activation in the absence of T cell receptor/CD3 occupancy.

1993 • 52 citations

Cooperation between an anti-T cell (anti-CD28) monoclonal antibody and monocyte-produced IL-6 in the induction of T cell responsiveness to IL-2.

1988 • 50 citations

IL-7 supports the generation of cytotoxic T lymphocytes from thymocytes. Multiple lymphokines required for proliferation and cytotoxicity.

1990 • 49 citations

Characteristics of secondary cytotoxic T-cell responses in mice infected with influenza A viruses

1978 • 47 citations

Memory alloreactive cytotoxic T cells do not require costimulation for activation in vitro

1996 • 46 citations

Aspects of Cytotoxic T Cell Memory

1996 • 42 citations

IL-2-independent activity of IL-7 in the generation of secondary antigen-specific cytotoxic T cell responses in vitro.

1993 • 41 citations

In vivo response of mature T cells to Mlsa antigens. Long-term progeny of dividing cells include cells with a naive phenotype.

1996 • 38 citations

Specificity and editing by apoptosis of virus-induced cytotoxic T lymphocytes

1994 • 36 citations

Induction of primary anti‐viral cytotoxic T cells by in vitro stimulation with short synthetic peptide and interleukin‐7

1992 • 32 citations

Cross-reactivity patterns of murine cytotoxic T lymphocytes

1979 • 32 citations

TCR-independent activation of human CD4+ 45RO- T cells by anti-CD28 plus IL-2: Induction of clonal expansion and priming for a Th2 phenotype.

1996 • 25 citations

Immune responses to H-2Kd antigen expressed by recombinant vaccinia virus.

1986 • 25 citations

Recognition by major histocompatibility complex class I‐restricted cytolytic T lymphocytes of cells expressing vaccinia‐encoded viral and class I proteins

1987 • 16 citations

Specific epitope‐induced conversion of CD8⁺ memory cells into effector cytotoxic T lymphocytes in vitro: presentation of peptide antigen by CD8⁺ T cells

1992 • 13 citations

In vivo administration of major histocompatibility complex class I‐specific peptides from influenza virus induces specific cytotoxic T cell hyporesponsiveness

1993 • 8 citations